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In silico homology modeling of dengue virus non-structural 4B (NS4B) protein and its molecular docking studies using triterpenoids
BackgroundDengue fever has become a significant worldwide health concern, because of its high morbidity rate and the potential for an increase in...
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Examining geographical inequalities for malaria outcomes and spending on malaria in 40 malaria-endemic countries, 2010–2020
BackgroundWhile substantial gains have been made in the fight against malaria over the past 20 years, malaria morbidity and mortality are marked by...
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Genetic diversity and prevalence of emerging Rickettsiales in Yunnan Province: a large-scale study
BackgroundRickettsia and related diseases have been identified as significant global public health threats. This study involved comprehensive field...
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High rates of benzimidazole-resistance-associated alleles in Haemonchus contortus and detection of resistance against macrocyclic lactones in strongylids from German alpaca herds
The population of South American camelids (SAC) has been steadily growing in Europe, where they are confronted with the regional endoparasite...
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Description of Babesia galileei sp. nov. A Piroplasmid species causing severe disease in domestic cats
BackgroundBabesiosis is a tick-borne infection caused by piroplasmid protozoa and associated with anemia and severe disease in humans, domestic...
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Evaluation and comparison of one-step real-time PCR and one-step RT-LAMP methods for detection of SARS-CoV-2
BackgroundThere is an increasing disease trend for SARS-COV-2, so need a quick and affordable diagnostic method. It should be highly accurate and...
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Effect of Microsporidia MB infection on the development and fitness of Anopheles arabiensis under different diet regimes
BackgroundMicrosporidia MB ( MB ) is a naturally occurring symbiont of Anopheles and has recently been identified as having a potential to inhibit the...
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Assessment of COVID-19 risk factors of early and long-term mortality with prediction models of clinical and laboratory variables
BackgroundCoronavirus disease (COVID-19) may lead to serious complications and increased mortality. The outcomes of patients who survive the early...
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Prevalence of vitamin D deficiency and the effect of vitamin D3 supplementation on response to anti-tuberculosis therapy in patients with extrapulmonary tuberculosis
BackgroundWe aimed to assess serum 25-hydroxyvitamin D3 (25(OH)D3) concentrations in extrapulmonary tuberculosis (EPTB) patients and to evaluate the...
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Prevalence and mechanisms of aminoglycoside resistance among drug-resistant Pseudomonas aeruginosa clinical isolates in Iran
BackgroundAminoglycosides have been a cornerstone of the treatment of nosocomial infections caused by Pseudomonas aeruginosa for over 80 years....
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Prevalence and associated factors of schistosomiasis among pregnant women in northern Senegal
BackgroundSchistosomiasis remains a public health concern worldwide. It is responsible for more than 240 million cases in 78 countries, 40 million of...
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Evaluation of the sentinel yellow fever surveillance system in Uganda, 2017–2022: strengths and weaknesses
BackgroundUganda has a sentinel surveillance system in seven high-risk sites to monitor yellow fever (YF) patterns and detect outbreaks. We evaluated...
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Deployment of attractive targeted sugar baits in western Zambia: installation, monitoring, removal, and disposal procedures during a Phase III cluster randomized controlled trial
BackgroundAttractive Targeted Sugar Baits (ATSBs) offer a complementary vector control strategy to interventions targeting blood feeding or larval...
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One-year survival of patients admitted for sepsis to intensive care units in Colombia
BackgroundSepsis is a frequent cause of admission to intensive care units (ICUs). High mortality rates are estimated globally, and in our country,...
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A new diagnostic technique for identifying Angiostrongylus spp. larvae in intermediate snail species by examining the buccal cavity
BackgroundAngiostrongyliasis is a zoonotic parasitic disease caused by the rat lungworm Angiostrongylus cantonensis . The intermediate hosts of A....
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Rapid diagnosis of alveolar echinococcosis from lung puncture sample using metagenomic next-generation sequencing: a case report
IntroductionAlveolar echinococcosis (AE), caused by the larval forms of Echinococcus multilocularis , is a zoonotic disease affecting the liver,...
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Discovery of antimalarial drugs from secondary metabolites in actinomycetes culture library
BackgroundNatural products play a key role as potential sources of biologically active substances for the discovery of new drugs. This study aimed to...
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Cytomorphological patterns and clinical features of presumptive tubercular lymphadenitis patients and their comparison with bacteriological detection methods: a cross-sectional study
IntroductionTuberculous lymphadenitis (TBLN) is an infection of the lymph node caused by Mycobacterium tuberculosis . Histological diagnoses of...
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Two decades of molecular surveillance in Senegal reveal rapid changes in known drug resistance mutations over time
BackgroundDrug resistance in Plasmodium falciparum is a major threat to malaria control efforts. Pathogen genomic surveillance could be invaluable...
