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The effect of four loading intravitreal aflibercept injections on macular fluid in treatment-naïve neovascular age-related macular degeneration
PurposeTo evaluate the effect of four versus three loading aflibercept injections on macular fluid resolution and visual acuity (VA) in exudative...
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The use of transcutaneous electrical acupoint stimulation to reduce opioid consumption in patients undergoing off-pump CABG: a randomized controlled trial
BackgroundHigh doses of long-acting opioids were used to facilitate off-pump coronary artery bypass grafting procedure, which may result in...
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Instrumentless liver suspension for liver retraction in robotic pancreatoduodenectomy
The popularity of robotic pancreatoduodenectomy (RPD) is increasing, yet it remains a complex procedure. Outcomes are influenced by various factors,...
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Stem cell therapy in diabetic men with erectile dysfunction: a 24-month follow-up of safety and efficacy of two intracavernous autologous bone marrow derived mesenchymal stem cells injections, an open label phase 2 clinical trial
BackgroundRecently we reported results of phase 1 pilot clinical trial of 2 consecutive intracavernous (IC) injection of autologous bone...
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Risk of hepatocellular carcinoma occurrence after antiviral therapy for patients with chronic hepatitis C Infection: a systematic review and meta-analysis
Background and AimsThe risk of hepatocellular carcinoma (HCC) occurrence following antiviral therapy in patients with chronic hepatitis C (CHC)...
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Assessment of objective visual function following idebenone administration in patients with leber hereditary optic neuropathy
PurposeTo objectively assess visual function in Leber’s Hereditary Optic Neuropathy (LHON) patients; this study evaluated pre- and post-idebenone...
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Establishment of an ovarian cancer exhausted CD8+T cells-related genes model by integrated analysis of scRNA-seq and bulk RNA-seq
Ovarian cancer (OC) was the fifth leading cause of cancer death and the deadliest gynecological cancer in women. This was largely attributed to its...
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Surveillance for Distant Metastasis in Breast Cancer Patients Who Underwent Contemporary Management: A Report from the Korean Breast Cancer Society Survivor Research Group
BackgroundCurrent guidelines recommend against the use of routine imaging tests to detect distant metastasis in asymptomatic breast cancer patients....
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Prognostic Relevance of the Proximal Resection Margin Distance in Distal Gastrectomy for Gastric Adenocarcinoma
BackgroundThe risk for recurrence in patients with distal gastric cancer can be reduced by surgical radicality. However, dispute exists about the...
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Uterine Anastomosis with Low Anterior Resection
In this surgical teaching video, we demonstrate the technique of robot-assisted uterine anastomosis combined with low anterior resection in a...
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A comparative assessment of ACS NSQIP-predicted and actual surgical risk outcomes of robotic transhiatal esophagectomy for esophageal adenocarcinoma resection at a high volume institution
Esophageal adenocarcinoma incidence is increasing in Western nations. There has been a shift toward minimally invasive approaches for transhiatal...
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The origin of ovarian Leydig cells: a possibly solved enigma?
Over the years, the origin of ovarian Leydig cells has been, and still is, a topic subject to deep debate. Seven years ago, we proposed that this...
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A streamlined method to generate endothelial cells from human pluripotent stem cells via transient doxycycline-inducible ETV2 activation
The development of reliable methods for producing functional endothelial cells (ECs) is crucial for progress in vascular biology and regenerative...
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The use of postoperative calibrations in Hirschsprung disease: a practice to reconsider?
PurposeDaily postoperative anal dilations after endorectal pull-through for Hirschsprung disease (HD) are still considered a common practice. We...
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The wide-awake local anesthesia no tourniquet (WALANT) technique in thumb injuries: a systematic review
Human hands have a complex anatomical structure. The thumb, being an integral part of the hand, has an essential function in grip**. In this sense,...
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Current Surveillance and Treatment Guidelines for Thyroid Carcinoma
Purpose of ReviewAlthough thyroid nodules are often a common finding during examination of the thyroid gland, with a prevalence of approximately 5%...
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M2-type tumor-associated macrophages upregulated PD-L1 expression in cervical cancer via the PI3K/AKT pathway
Background and purposePD-1/PD-L1 inhibitors have become a promising therapy. However, the response rate is lower than 30% in patients with cervical...