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Graphene oxide electrodes enable electrical stimulation of distinct calcium signalling in brain astrocytes
Astrocytes are responsible for maintaining homoeostasis and cognitive functions through calcium signalling, a process that is altered in brain...
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Yoda1 pretreated BMSC derived exosomes accelerate osteogenesis by activating phospho-ErK signaling via Yoda1-mediated signal transmission
Segmental bone defects, arising from factors such as trauma, tumor resection, and congenital malformations, present significant clinical challenges...
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An end-to-end approach for single-cell infrared absorption spectroscopy of bacterial inclusion bodies: from AFM-IR measurement to data interpretation of large sample sets
BackgroundInclusion bodies (IBs) are well-known subcellular structures in bacteria where protein aggregates are collected. Various methods have...
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In silico-guided discovery and in vitro validation of novel sugar-tethered lysinated carbon nanotubes for targeted drug delivery of doxorubicin
ContextMultiwalled carbon nanotubes (MWCNTs) functionalized with lysine via 1,3-dipolar cycloaddition and conjugated to galactose or mannose are...
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A comparative study on the effect of nano-additives on the performance and emissions of a diesel engine run on palm biodiesel
Rising energy requirements in conjunction with the diminishment of fossil fuels and an accelerated pace of fuel consumption, combined with the...
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Green sonochemical synthesis of ZnCo2O4 decorated with carbon nanofibers for enhanced electrochemical detection of bisphenol A in food products
The facile sonochemical synthesis is reported of zinc cobalt oxide (ZnCo 2 O 4 ) composited with carbon nanofiber (CNF). Structural, chemical, and...
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Microfluidic synthesis of alginate co-polymeric microgels for enhanced protein delivery applications
Alginate-based microcapsules are promising carriers for drugs and biomedical agents due to their biodegradability, biocompatible character, and easy...
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The obesity-related mutation gene on nonalcoholic fatty liver disease
The prevalence of overweight and obesity is increasing, leading to metabolic-associated fatty liver disease (MAFLD) characterized by excessive...
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Ultrafast Response and Threshold Adjustable Intelligent Thermoelectric Systems for Next-Generation Self-Powered Remote IoT Fire Warning
Fire warning is vital to human life, economy and ecology. However, the development of effective warning systems faces great challenges of fast...
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Stabilization of the stainless-steel interface using sequentially deposited Al2O3 nano films using atomic layer deposition (ALD) technique
Atomic layer deposition (ALD) has been an important surface processing technique of materials of important applications. In the present investigation...
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Defect-engineered chiral metal–organic frameworks
Chirality has an important impact on chemical and biological research, as most active substances are chiral. In recent decades, metal–organic...
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Causal inference of the effect of blood proteome on the risk of head and neck cancer: two-sample Mendelian randomization
Early diagnosis of head and neck cancer can improve therapeutic outcomes but remains a challenge. The blood proteome can comprise a key source of...
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Association between dietary (poly)phenol intake and the ATHLOS Healthy Ageing Scale in the Polish arm of the HAPIEE study
Inverse association between (poly)phenol intake and age-related disorders has been demonstrated; however, little is known whether they affect...
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Genomic variants associated with age at diagnosis of childhood-onset type 1 diabetes
Age at diagnosis (AAD) of Type 1 diabetes (T1D) is determined by the age at onset of the autoimmune attack and by the rate of beta cell destruction...
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Understanding epitaxial growth of two-dimensional materials and their homostructures
The exceptional physical properties of two-dimensional (2D) van der Waals (vdW) materials have been extensively researched, driving advances in...
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Multidimensionally Nano-topologized Polycaprolactone Fibrous Membrane Anchored with Bimetallic Peroxide Nanodots for Microenvironment-Switched Treatment on Infected Diabetic Wounds
Delayed healing of diabetic wounds poses a major challenge to human health due to severe vascular dysfunction, sustained inflammation, and...
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Pears classification by identifying internal defects based on X-ray images and neural networks
In order to increase the sales and profitability, it is essential to classify the pears according to the external morphology (including shape, color...
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Cutting performance and effectiveness evaluation on organic monolayer embrittlement in ductile metal precision machining
In the traditional machining field, the addition of cutting fluid can appropriately reduce cutting forces, dissipate cutting heat, and facilitate the...
