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Can nutritional scores improve the WHO calibrated non-laboratory risk prediction model for cardiovascular disease? Golestan Cohort Study
PurposeEvaluation of the added value of Dietary Approaches to Stop Hypertension (DASH) and Mediterranean diet scores on the prediction model of the...
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Efficacy and safety of romosozumab: a meta-analysis of placebo-controlled trials
IntroductionWe aimed to comprehensively compile placebo-controlled trials on the efficacy and safety of romosozumab (210 mg, subcutaneously, once...
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AI-based selection of individuals for supplemental MRI in population-based breast cancer screening: the randomized ScreenTrustMRI trial
Screening mammography reduces breast cancer mortality, but studies analyzing interval cancers diagnosed after negative screens have shown that many...
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Impact of fish oil supplementation on plasma levels of highly unsaturated fatty acid-containing lipid classes and molecular species in American football athletes
BackgroundPrevious studies have linked sports-related concussions and repeated subconcussive head impacts in contact sport athletes to elevated brain...
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The interplay between diabetes Mellitus and soft tissue infections in general surgical patients
BackgroundDiabetes mellitus (DM) is a worldwide pandemic affecting 500 million people. It is known to be associated with increased susceptibility to...
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The impact of a culturally adapted lifestyle intervention on the glycaemic profile of mothers with GDM one year after delivery – a community-based, cluster randomized trial in Sri Lanka
BackgroundA woman with a history of GDM has a high risk of develo** type two diabetes (T2DM) in her future life. Lifestyle modifications are known...
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Subclinical dose irradiation triggers human breast cancer migration via mitochondrial reactive oxygen species
BackgroundDespite technological advances in radiotherapy, cancer cells at the tumor margin and in diffusive infiltrates can receive subcytotoxic...
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Heterotypic macrophages/microglia differentially contribute to retinal ischaemia and neovascularisation
Aims/hypothesisDiabetic retinopathy is characterised by neuroinflammation that drives neuronal and vascular degenerative pathology, which in many...
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Mechanisms of osteoporosis associated with chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a disease characterized by chronic respiratory symptoms due to inflammatory and destructive changes...
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iTRAQ proteomics analysis of placental tissue with gestational diabetes mellitus
BackgroundGestational diabetes mellitus is an endocrine and metabolic disorder that appears for the first time during pregnancy and causes varying...
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Uncommon adrenal rest tumors and massive adrenal enlargement in adult with congenital adrenal hyperplasia mimicking metastasis from pleomorphic sarcoma
BackgroundCongenital adrenal hyperplasia (CAH) encompassed a bunch of autosomal recessive disorders characterized by impaired cortisol levels due to...
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Sparing confirmatory testing in primary aldosteronism (SCIPA): a multicenter retrospective diagnostic accuracy study
BackgroundThe diagnosis of primary aldosteronism (PA) is comprehensive, which includes case-detection testing, case confirmation followed by subtype...
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A systematic review and meta-analysis of nonrelapse mortality after CAR T cell therapy
Although chimeric antigen receptor (CAR) T cell therapy represents a transformative immunotherapy, it is also associated with distinct toxicities...
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Safety of pulsed field ablation in more than 17,000 patients with atrial fibrillation in the MANIFEST-17K study
Pulsed field ablation (PFA) is an emerging technology for the treatment of atrial fibrillation (AF), for which pre-clinical and early-stage clinical...
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Incidence of four major osteoporotic fragility fractures among older individuals in Sado, Japan, in 2020
IntroductionThis study compared the 2020 incidence of fragility fractures in Sado City with those from 2004 to 2015.
Materials and methods ...
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Novel genomic variants related to visceral adiposity index (VAI) and body adiposity index (BAI) in Indian sib-pairs
BackgroundObesity is among the leading public health threats globally. Over the last few years, visceral adiposity index (VAI), and body adiposity...
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A closer look at Galectin-3: its association with gestational diabetes mellitus revealed by systematic review and meta-analysis
PurposeGestational diabetes mellitus (GDM) represents a significant metabolic disorder that affects pregnant women worldwide and has negative...
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Taking care of inpatients with fragility hip fractures: the hip-padua osteosarcopenia (Hip-POS) fracture liaison service model
PurposeOsteoporotic fragility fractures (FF), particularly those affecting the hip, represent a major clinical and socio-economic concern. These...
