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Antibacterial activity and biosynthetic potential of Streptomyces sp. PBR19, isolated from forest rhizosphere soil of Assam
An Actinomycetia isolate, designated as PBR19, was derived from the rhizosphere soil of Pobitora Wildlife Sanctuary (PWS), Assam, India. The isolate,...
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Network analysis of gut microbial communities reveal key genera for a multiple sclerosis cohort with Mycobacterium avium subspecies paratuberculosis infection
BackgroundIn gut ecosystems, there is a complex interplay of biotic and abiotic interactions that decide the overall fitness of an individual....
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Epidemiology of biliary tract-associated bloodstream infections and adequacy of empiric therapy: an Australian population-based study
PurposeAlthough the biliary tract is a common source of invasive infections, the epidemiology of cholangitis- and cholecystitis-associated...
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A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human health, causing pandemics with high mortality and...
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In silico homology modeling of dengue virus non-structural 4B (NS4B) protein and its molecular docking studies using triterpenoids
BackgroundDengue fever has become a significant worldwide health concern, because of its high morbidity rate and the potential for an increase in...
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Mutational Improvement of the Lactobacillus delbrueckii subsp. lactis Biopreservation Potential
AbstractThe primary objective of this study was to develop tools and strategies aimed at enhancing the synthesis of hydrogen peroxide in Lactobacillus...
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LSPR-based Colorimetric Aptasensor Design for Rapid and Simple Detection of Vibrio cholerae O1
AbstractIn recent years, the prevalence of intestinal diseases, particularly Vibrio cholerae , has been on the rise, leading to numerous epidemics...
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Biochemical Characterization and Electrochemical Cultivation of Halotolerant Autotrophic Iron-Oxidizing Bacteria Isolated from Electroplating Wastewater Sludge in Japan
AbstractThe aerobic and rod-shaped FO1 strain of iron-oxidizing bacteria was isolated from electroplating wastewater sludge using colloidal silica...
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Liver X receptor inverse agonist SR9243 attenuates rheumatoid arthritis via modulating glycolytic metabolism of macrophages
Liver X receptors (LXRs) which link lipid metabolism and inflammation, were overexpressed in experimental rheumatoid arthritis (RA) rats as observed...
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Undibacterium cyanobacteriorum sp. nov., an auxin-producing bacterium isolated from fresh water during cyanobacterial bloom period
A novel Gram-negative, white-pigmented, and auxin-producing strain, 20NA77.5 T , was isolated from fresh water during cyanobacterial bloom period....
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Survey on Perkinsus species in two economic mussels (Mytilus coruscus and M. galloprovincialis) along the coast of the East China Sea and the Yellow Sea
Perkinsus , a parasitic pathogen of marine bivalves, is widely distributed among various mollusks in numerous countries. However, the prevalence and...
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Molecular characterizations of Cryptosporidium spp. in brown rat (Rattus norvegicus) from an animal feedlot in **njiang, China
Cryptosporidium infection is a common occurrence in rodents worldwide. In this study, 435 wild brown rats were captured from an animal feedlot in...
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Concomitant Production and Utilization of Thermoacidic Phytases from Pichia kudriavzevii FSMP-Y17 in Broilers Feed
AbstractProduction of phytases from Pichia kudriavzevii FSMP-Y17 yeast was enhanced by optimization of the fermentation variables under submerged...
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Degradation of High-density Polyethylene Mediated by Fungus Talaromyces liani JA2HS
AbstractHigh density polyethylene (HDPE) waste accumulation in the environment is one among the major threats faced globally for the last quarter of...
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Improving the Thermostability and Catalytic Performance of the Bacillus subtilis Chitosanase BsCsn46A via Computational Design
AbstractChitosanase plays a pivotal role in the production of chitooligosaccharide. Nevertheless, there is untapped potential for enhancing both its...
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An Antitermitic Compound-Producing Endophytic Bacterium from Chamaecyparis lawsoniana
AbstractTermites present a significant hazard to wooden structures, agriculture and urban environments. Termiticides are now required to meet more...
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Alkaline Proteases from Haloalkaliphiles: Unveiling Nature’s Catalysts for Diverse Applications
AbstractAlkaline proteases derived from haloalkaliphiles, extremophilic microorganisms thriving in high-pH and high-salt environments, have garnered...
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Assessment of COVID-19 risk factors of early and long-term mortality with prediction models of clinical and laboratory variables
BackgroundCoronavirus disease (COVID-19) may lead to serious complications and increased mortality. The outcomes of patients who survive the early...
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E2F1 Facilitates the Proliferation and Stemness of Gastric Cancer Cells by Activating CDC25B Transcription and Modulating the MAPK Pathway
Gastric cancer (GC) is a health problem that concerns people around the world. CDC25B is an essential cell cycle regulatory factor that is...
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Enhancement of the structure and biochemical function of cyclomaltodextrinase from the Anoxybacillus flavithermus ZNU-NGA with site-directed mutagenesis
This study was conducted to examine the role of the central domain of cyclomaltodextrinase in terms of stability, substrate specificity, becoming...
