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Ellagic acid as potential therapeutic compound for diabetes and its complications: a systematic review from bench to bed
Diabetes mellitus (DM) is a worldwide-concerning disease with a rising prevalence. There are many ongoing studies aimed at finding new and effective...
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Assessment of COVID-19 risk factors of early and long-term mortality with prediction models of clinical and laboratory variables
BackgroundCoronavirus disease (COVID-19) may lead to serious complications and increased mortality. The outcomes of patients who survive the early...
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Open Access: Opening or Closing Doors for Junior Faculty?
The Open Access movement has transformed the landscape of medical publishing. Federal regulations regarding Open Access have expanded in the USA, and...
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Perioperative complications of middle cerebral artery occlusion in rats alleviated by human umbilical cord mesenchymal stem cells
For acute ischemic stroke treatment, the limitations of treatment methods and the high incidence of perioperative complications seriously affect the...
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Dual-energy CT in differentiating benign gallbladder wall thickening from wall thickening type of gallbladder cancer
ObjectiveTo evaluate the performance of dual-energy computed tomography (DECT) in differentiating non-acute benign from malignant gallbladder wall...
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Race as a Risk Marker, Not a Risk Factor: Revising Race-Based Algorithms to Protect Racially Oppressed Patients
Emerging consensus in the medical and public health spheres encourages removing race and ethnicity from algorithms used in clinical decision-making....
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Investigation of macro and micro sleep structures of first night effect in school-aged children
This study aimed to investigate the occurrence and age-related changes of the first night effect (FNE) in school-age children using both macro (sleep...
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The gut–pancreas axis: investigating the relationship between microbiota metabolites and pancreatic steatosis
The prevalence of pancreatic steatosis has increased and it has been linked to the rising prevalence of metabolic syndrome. Metabolic syndrome is...
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Evaluation and comparison of one-step real-time PCR and one-step RT-LAMP methods for detection of SARS-CoV-2
BackgroundThere is an increasing disease trend for SARS-COV-2, so need a quick and affordable diagnostic method. It should be highly accurate and...
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Autism spectrum: parents’ perspectives reflecting the different needs of different families
BackgroundParents of children on the autism spectrum often face great challenges in the care of their child. Early support tailored to families’...
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CYP24A1 Deficiency Mimicking Other Causes of Hypercalciuria and Nephrocalcinosis: A Case Report
In this report, we discuss the case of a 54-year-old patient attending our department with osteopenia, urolithiasis, significant hypercalciuria, and...
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ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer’s disease mouse model
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer’s disease (AD). Aberrations in GABAergic function and the...
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Dermotoscope assisted diagnosis of adolescent bullous pilomatricoma: six case reports
BackgroundPilomatricoma (PM) is a cutaneous benign neoplasm derived from the hair matrix. It clinically presents as a solitary and firm nodule...
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Identifying SCS Trial Responders Immediately After Postoperative Programming with ECAP Dose-Controlled Closed-Loop Therapy
IntroductionDrawbacks of fixed-output spinal cord stimulation (SCS) screening trials may lead to compromised trial outcomes and poor predictability...
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Methylprednisolone Modulates the Tfr/Tfh ratio in EAE-Induced Neuroinflammation through the PI3K/AKT/FoxO1 and PI3K/AKT/mTOR Signalling Pathways
Methylprednisolone (MP) is a potent glucocorticoid that can effectively inhibit immune system inflammation and brain tissue damage in Multiple...
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Skin carotenoid scores and metabolic syndrome in a general Japanese population: the Hisayama study
BackgroundHigher vegetable intake is being promoted as an initiative to prevent lifestyle-related diseases. Carotenoids are yellow or red pigment...
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Dissecting the vascular-cognitive nexus: energetic vs. conventional hemodynamic parameters
Blood pressure or flow measurements have been associated with vascular health and cognitive function. We proposed that energetic hemodynamic...
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Short and long-term acceptability and efficacy of extended-release cornstarch in the hepatic glycogen storage diseases: results from the Glyde study
BackgroundHypoglycaemia is the primary manifestation of all the hepatic types of glycogen storage disease (GSD). In 2008, Glycosade ® , an...
