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A phase 3, randomized, double-blind, multicenter, placebo-controlled study of S-588410, a five-peptide cancer vaccine as an adjuvant therapy after curative resection in patients with esophageal squamous cell carcinoma
BackgroundS-588410, a cancer peptide vaccine (CPV), comprises five HLA-A*24:02-restricted peptides from five cancer-testis antigens. In a phase 2...
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Left anterior mini-thoracotomy: an alternative approach for pulmonary valve replacement after surgically corrected tetralogy of fallot
IntroductionPulmonary regurgitation (PR) remains a common sequela in patients following surgically corrected TOF, and may lead to progressive right...
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Die neoadjuvante Immunchemotherapie des nichtkleinzelligen Lungenkarzinoms: Was Thoraxchirurginnen und -chirurgen wissen müssen
Neoadjuvant immunotherapy is a promising treatment for non-small cell lung cancer (NSCLC), a disease for which the prognosis has improved little...
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The effect of mass functionality on laparoscopic adrenalectomy outcomes
PurposeThis study aimed to determine the effect of adrenal mass functionality and different hormone subtypes synthesized by the adrenal masses on...
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Revolutionizing thoracic surgery education: a bibliometric analysis of the past decade’s literature
ObjectivesThoracic surgery is a complex field requiring advanced technical skills and critical decision-making. Surgical education must evolve to...
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Patent conversion of a novel closed chest drainage device
Closed chest drainage is typically necessary following Lobar and Sublobar resections to evacuate gases and fluids from the thoracic cavity, eliminate...
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Outcomes of maze procedure and mitral valve surgery in atrial functional mitral regurgitation: a retrospective study
BackgroundAtrial functional mitral regurgitation (AFMR) is a newly discovered condition associated with longstanding atrial fibrillation. This...
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6,126 hepatectomies in 2022: current trend of outcome in Italy
PurposeWhether hospital volume affects outcome of patients undergoing hepatobiliary surgery, and whether the centralization of such procedures is...
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Long-term mortality after isolated coronary artery bypass grafting and risk factors for mortality
BackgroundPatients requiring coronary artery bypass grafting (CABG) have multiple co-morbidities which need to be considered in totality when...
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Multicenter retrospective analysis of complications and risk factors in endoscopic resection for esophageal cancer across Japan
BackgroundEndoscopic resection (ER) is a minimally invasive treatment for esophageal cancer that sometimes causes complications. To understand the...
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Perventricular device closure of the ventricular septal defects in children-first experience in the United Arab Emirates
BackgroundVentricular septal defect (VSD) is the most common congenital cardiac malformation, accounting for approximately 30% of congenital heart...
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Total pulmonary arterial reconstruction in a patient with arterial tortuosity syndrome affecting the pulmonary artery: a case report and review of the literature
BackgroundArterial tortuosity syndrome is a rare Autosomal recessive disease that leads to a loss of function of the connective tissues of the body,...
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Response to chemotherapy could predict the prognosis of esophageal squamous cell carcinoma treated with neoadjuvant docetaxel, cisplatin, and fluorouracil (DCF) followed by surgery: long-term results in a single institute
BackgroundPreoperative chemotherapy with 5-fluorouracil and cisplatin (FP) followed by surgery has been considered a standard treatment for patients...
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A comparative study of shockwave intravascular lithotripsy and conventional percutaneous coronary intervention in the treatment of severe coronary artery calcification lesions
BackgroundThe purpose of this study was to evaluate the effectiveness of intravascular lithotripsy (IVL) in the treatment of severe coronary artery...
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The world of statistics through the eyes of a practising cardiac surgeon
In modern scientific literature, the dominant role of statistical rigor is undeniable. However, the methodology and the language behind this science...
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The Therapeutic Effect of Bleomycin Sclerotherapy in Vascular Malformations
Sclerotherapy is a frequently employed technique for treating vascular malformations. Bleomycin is a sclerosant that has demonstrated efficacy and...
