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Ruxolitinib Cream in Adolescents/Adults with Atopic Dermatitis Meeting Severity Thresholds for Systemic Therapy: Exploratory Analysis of Pooled Results from Two Phase 3 Studies
IntroductionStandard therapy for patients with mild to moderate atopic dermatitis (AD) typically includes topical therapies; however, patients with...
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Exploring paramedics’ lived experiences in confrontation with patients’ death during missions: a phenomenological study
BackgroundEmergency personnel are the first line of emergency response systems to respond to emergencies; in essence, they are usually exposed to a...
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Improving the introduction of telemedicine in pre-hospital emergency medicine: understanding users and how acceptability, usability and effectiveness influence this process
IntroductionIncreasing numbers of ambulance calls, vacant positions and growing workloads in Emergency Medicine (EM) are increasing the pressure to...
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Etablierung eines multiprofessionellen Primärversorgungszentrums – Erkenntnisse aus einer begleitenden Evaluation
BackgroundInterprofessional primary care centers are proposed in order to meet future demands on healthcare. This can improve coordination between...
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Resilience after severe critical illness: a prospective, multicentre, observational study (RESIREA)
BackgroundCritical-illness survivors may experience post-traumatic stress disorder (PTSD) and quality-of-life impairments. Resilience may protect...
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Complications of Superomedial Versus Inferior Pedicle Reduction Mammaplasty: A Systematic Review and Meta-Analysis
BackgroundThe superomedial pedicle reduction mammoplasty has gained popularity and is an important alternative approach for reduction mammoplasty,...
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Cross-linked Sodium Hyaluronate Gel with PLLA-b-PEG Microsphere for Facial Contouring in Chinese: A Retrospective Study
BackgroundIn Asia, the demand for cosmetic facial treatments has surged due to technological advancements, increased social acceptability, and...
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Discussion of EMA Draft Guideline on Quality and Equivalence of Topical Products Based on Comparison of Approved Mometasone Furoate Drugs
IntroductionToday, the approval for a generic topical product includes the presentation of therapeutic equivalence to the originator based on...
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Optimization of kidney function in cardiac surgery patients with intra-abdominal hypertension: expert opinion
Cardiac surgery-associated acute kidney injury (CSA-AKI) affects up to 42% of cardiac surgery patients. CSA-AKI is multifactorial, with low abdominal...
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Does the site, size, and number of necrotic collections affect the outcome of necrotizing pancreatitis? – a prospective analysis
PurposeIn patients with acute necrotizing pancreatitis (ANP), the site, size, and the number of acute necrotic collections (ANC) may determine the...
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Incisional negative pressure wound therapy (PrevenaTM) vs. conventional post-operative dressing after immediate breast reconstruction: a randomized controlled clinical trial
BackgroundSurgical complications following breast reconstruction remain a significant concern. This study aimed to investigate if incisional negative...
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Traumatische Hemipelvektomie
The challenge in treating traumatic hemipelvectomy is the dynamics of the complex and life-threatening consequences of the injury. These include skin...
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Key performance indicators in pre-hospital response to disasters and mass casualty incidents: a sco** review
PurposeThe objective of this study was to offer a comprehensive synthesis of the existing Key performance indicators (KPIs) used in the evaluation of...
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Efficacy and Safety of Corticosteroid in Combination with 5-Fluorouracil in the Treatment of Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis
BackgroundAddressing hypertrophic scars and keloids poses a significant challenge in the realm of preventive and curative medicine. Combination...
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Temporary Declines and Demand Resurgence: Gender-Affirming Surgery Volume and Complication Trends During and After the COVID-19 Pandemic
BackgroundThe COVID-19 pandemic prompted surgical volume reductions due to lockdown measures. This study evaluates COVID-19’s impact on...
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Berufskrankheiten mit Bezug zur HNO-Heilkunde
In the German Ordinance on Occupational Diseases (BKV), there are currently 82 occupational diseases listed, of which 18 partially or completely fall...
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Lower or higher oxygenation targets in the intensive care unit: an individual patient data meta-analysis
PurposeOptimal oxygenation targets for patients with acute hypoxemic respiratory failure in the intensive care unit (ICU) are not clearly defined due...
