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Rutin Ameliorates Toxoplasma gondii-Induced Brain Tissue Damage via Inhibiting P2X7R/NLRP3 Pro-Inflammatory and Enhancing PI3K/AKT/Nrf2/HO-1 Antioxidant Signaling Pathway
AbstractBain damage caused by Toxoplasma gondii ( T. gondii ) is associated with increased inflammatory response and oxidative stress. Rutin, a...
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Exposure to PM2.5 and its constituents is associated with metabolic dysfunction-associated fatty liver disease: a cohort study in Northwest of China
Accumulating animal studies have demonstrated associations between ambient air pollution (AP) and metabolic dysfunction-associated fatty liver...
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Inter-zonal epithelial thickness differences for early keratoconus detection using optical coherence tomography
PurposeTo develop and test a parameter for early keratoconus screening by quantifying the localized epithelial thickness differences in keratoconic...
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Investigating the impact of urban-environmental factors on air pollutants: a land use regression model approach and health risk assessment
The presence of pollutants in the earth's atmosphere has a direct impact on human health and the environment. So that pollutants such as carbon...
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Fine map** of interspecific secondary CSSL populations revealed key regulators for grain weight at qTGW3.1 locus from Oryza nivara
Grain weight (GW) is the most important stable trait that directly contributes to crop yield in case of cereals. A total of 105 backcross...
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Susceptibility gene mutations in germline and tumors of patients with HER2-negative advanced breast cancer
Germline mutations in BRCA1 and BRCA2 (g BRCA1/2 ) are required for a PARP inhibitor therapy in patients with HER2-negative (HER2−) advanced breast...
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Reassortment incompetent live attenuated and replicon influenza vaccines provide improved protection against influenza in piglets
Swine influenza A viruses (swIAV) cause an economically important respiratory disease in modern pig production. Continuous virus transmission and...
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Dissipation kinetics and the evaluation of dietary risks associated with deltamethrin, ethion, fenazaquin, and fenpropathrin on bell pepper (Solanum annuum L.)
Bell peppers, a globally significant crop, face infestations from various pests. In a study, bell peppers were treated with deltamethrin, ethion,...
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Control of paleoclimate and paleoweathering on chromium contents in a non-ultramafic aquifer hosting high chromium groundwater
Cr(VI) is a carcinogen with proven mutagenic and genotoxic effects. The effects of the depositional environment (e.g., paleoweathering, paleoclimate,...
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The Effect of Oxidative Stress and Antioxidants Treatment on Gestational Diabetes Mellitus Outcome: A Sco** Review
Diagnosing a pregnant woman’s glucose intolerance is referred to as gestational diabetes mellitus (GDM). Diabetes has been linked to enhanced...
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Impact of biochar produced at different pyrolysis conditions on heavy metal contaminated soil
This study aimed to assess the effectiveness of urban derived biochars such as Sugarcane bagasse (SB), Brinjal Stem (BS), and Citrus Peel (CP)...
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The impact of social media use on the relationship between social isolation and connectedness during COVID-19 in Hong Kong
The emergence of the COVID-19 pandemic has emphasised the importance of social connectedness, whilst the popularity of social media continues to...
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Association between brominated flame retardants (PBDEs and PBB153) exposure and hypertension in U.S. adults: results from NHANES 2005–2016
BackgroundBrominated Flame Retardants (BFRs) have attracted widespread concern due to their environmental persistence and potential toxicity. This...
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Association of low adherence to weekly cisplatin with outcomes in patients with head and neck squamous cell carcinoma: a retrospective cohort study
BackgroundThe National Comprehensive Cancer Network (NCCN) guideline recommends consideration of weekly cisplatin as an alternative option for...
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A comparative study of in vivo toxicity in zebrafish embryos synthesized CuO nanoparticles characterized from Salacia reticulata
The Salacia reticulata , a medicinal woody climbing shrub, was utilized for our study, the green synthesis of CuO nanoparticles, which were analyzed...
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The influence of sex-specific factors on biological transformations and health outcomes in aging processes
The aging process demonstrates notable differences between males and females, which are key factors in disease susceptibility and lifespan. The...
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Statistical methods for discrimination of STR genotypes using high resolution melt curve data
Despite the improvements in forensic DNA quantification methods that allow for the early detection of low template/challenged DNA samples,...
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Hearing and speech interactions in children with cerebral palsy, in the first 2 years
AbstractChildren with cerebral palsy (CP) face communication challenges stemming from neural lesions, hearing issues, and executive function...
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Efficacy and safety of glucocorticoids in the treatment of COVID-19: a systematic review and meta-analysis of RCTs
In the realm of acute respiratory infections, coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2...