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Sodium tanshinone IIA sulfonate protects vascular relaxation in ApoE-knockout mice by inhibiting the SYK-NLRP3 inflammasome-MMP2/9 pathway
BackgroundHyperlipidemia damages vascular wall and serves as a foundation for diseases such as atherosclerosis, hypertension and stiffness. The...
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A DPC Database Study on the Safety of Atezolizumab/Carboplatin/Etoposide in Extensive-Disease Small Cell Lung Cancer in Japanese Patients
IntroductionAtezolizumab, carboplatin, and etoposide (ACE) therapy is a standard of care for extensive-disease small cell lung cancer (SCLC);...
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Local impedance drop–guided versus lesion size index–guided pulmonary vein isolation
BackgroundLocal tissue impedance drop (LID) and lesion size index (LSI) technologies are valuable for predicting effective lesion formation. This...
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Evaluation of the diagnostic value of different serum biomarkers in girls with central precocious puberty
BackgroundAlarming trends show an increase in referrals of girls with suspected early puberty. However, variations in defining precocious puberty...
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Association between neural prosody discrimination and language abilities in toddlers: a functional near-infrared spectroscopy study
BackgroundLanguage delay affects near- and long-term social communication and learning in toddlers, and, an increasing number of experts pay...
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Nourishing Physical Productivity and Performance On a Warming Planet - Challenges and Nutritional Strategies to Mitigate Exertional Heat Stress
Purpose of ReviewClimate change is predicted to increase the frequency and severity of exposure to hot environments. This can impair health, physical...
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A Novel Diastolic Doppler Index Less Affected by Aortic Arch Anomalies Co-existing with Coarctation
Severity assessment for coarctation of the aorta (CoA) is challenging due to concomitant morphological anomalies (complex CoA) and inaccurate...
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Woven coronary artery with acquired etiology: the natural history documented by serial angiography and optical coherence tomography
Woven coronary artery (WCA) is a rare anomaly and its etiology remains speculative. Both congenital and acquired factors are considered to be...
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Social Support and Optimism in deaf and hard-of-hearing College Students: A Moderated Mediation Model of Belief about Adversity
PurposesFew studies focus on the mental health of deaf population. This study aims to explore the association between social support and optimism and...
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Novel physiologic predictors of positive airway pressure effectiveness (NICEPAP) study: rationale, design and methods
PurposeContinuous positive airway pressure (CPAP) is the primary therapy for obstructive sleep apnea (OSA); however the effectiveness of CPAP remains...
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Differentiating rhythmic high-amplitude delta with superimposed (poly) spikes from extreme delta brushes: limitations of standardized nomenclature and implications for patient management
BackgroundFollowing the standardized nomenclature proposed by the American Clinical Neurophysiology Society (ACNS), rhythmic high-amplitude delta...
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Initial surgery for spontaneous intestinal perforation in extremely low birth weight infants is not associated with mortality or in-hospital morbidities
ObjectiveDetermine short-term outcomes following peritoneal drain (PD), laparotomy (LAP) after PD (PD-LAP), and LAP in extremely low birth weight...
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Postoperative EEG abnormalities in relation to neurodevelopmental outcomes after pediatric cardiac surgery
BackgroundWe had reported that postoperative EEG background including sleep-wake cycle (SWC) and discharge (seizures, spikes/sharp waves)...
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Clinical Application of Different Doses of Hydromorphone Slow-Release Analgesia in Lumbar Fusion in Elderly Patients
IntroductionThe aim of this study is to examine the analgesic efficacy of varying doses of hydromorphone hydrochloride in conjunction with absorbable...
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Atrial fibrillation fact sheet in Korea 2024 (part 1): epidemiology of atrial fibrillation in Korea
Background and objectivesThis study aimed to analyze and present updated trends in atrial fibrillation (AF) epidemiology within the Korean...
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Clinical role of genetic testing for the Brugada syndrome overlap** with arrhythmogenic cardiomyopathy
BackgroundBrugada syndrome (BrS) and arrhythmogenic cardiomyopathy (ACM) are inherited cardiac diseases that may predispose to ventricular...
