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Comprehensive analysis of the association between triglyceride-glucose index and coronary artery disease severity across different glucose metabolism states: a large-scale cross-sectional study from an Asian cohort
BackgroundThe triglyceride-glucose (TyG) index is associated with the development and prognosis of coronary artery disease (CAD). However, the impact...
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Sodium tanshinone IIA sulfonate protects vascular relaxation in ApoE-knockout mice by inhibiting the SYK-NLRP3 inflammasome-MMP2/9 pathway
BackgroundHyperlipidemia damages vascular wall and serves as a foundation for diseases such as atherosclerosis, hypertension and stiffness. The...
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An elderly case of paraneoplastic anti-NMDA receptor encephalitis associated with large cell neuroendocrine carcinoma of the lung
BackgroundRecent studies have suggested that N-methyl-D-aspartate (NMDA) receptors are involved in the cell proliferation in several tumors. However,...
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How servant leadership influence employee spouses’ quality of family life: the social mindfulness lens
Work and family are closely interconnected domainsof human life. The past of three decades have witnessed the increasing research interest in...
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Exploring causes and predictors of cyberbullying in gifted and non-gifted students: Academic success, psychological variables, parental and educators’ supervision, motivation, and reactions to cyber victimization
The purpose of this study is to explore the motivation of cyberbullying behaviors, their reactions to these behaviors, and the predictors of...
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The others are harassers, but my loved ones are not: the effect of closeness on offender justification
People in one’s close circle are very meaningful to them. That is why people could defend their loved ones even if they committed a transgression as...
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A DPC Database Study on the Safety of Atezolizumab/Carboplatin/Etoposide in Extensive-Disease Small Cell Lung Cancer in Japanese Patients
IntroductionAtezolizumab, carboplatin, and etoposide (ACE) therapy is a standard of care for extensive-disease small cell lung cancer (SCLC);...
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Predictors of left atrial appendage thrombus in atrial fibrillation patients undergoing cardioversion
BackgroundAtrial fibrillation and atrial flutter represent the most prevalent clinically significant cardiac arrhythmias. While the CHA2DS2-VASc...
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Local impedance drop–guided versus lesion size index–guided pulmonary vein isolation
BackgroundLocal tissue impedance drop (LID) and lesion size index (LSI) technologies are valuable for predicting effective lesion formation. This...
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Self-organization of social hierarchies studied with Monte-Carlo simulations; self-destroying join-believe-fight system as an inevitable outcome
Monte-Carlo simulations were used to describe the interactions between cellular automata, socio-economic ‘agents’, in society. In a first simulation...
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Outcomes of deep venous thrombosis management and associated factors among patients in tertiary hospitals in Addis Ababa, Ethiopia: a multicenter retrospective cohort study
BackgroundPulmonary embolism (PE) and deep venous thrombosis (DVT) are the two most important manifestations of venous thromboembolism (VTE). DVT...
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Comprehensive Quality Analysis of Conventional and Novel Biomarkers in Diagnosing and Predicting Prognosis of Coronary Artery Disease, Acute Coronary Syndrome, and Heart Failure, a Comprehensive Literature Review
Coronary artery disease (CAD), acute coronary syndrome (ACS), and heart failure (HF) are major global health issues with high morbidity and mortality...
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Transcriptomic Expression of T2-Inflammation Genes in Peripheral Blood Mononuclear Cells and Longitudinal Clinical Outcomes in Asthma: Insights from the COREA Study
BackgroundGene expression can provide distinct information compared to clinical biomarkers in the context of longitudinal clinical outcomes in asthma...
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Nourishing Physical Productivity and Performance On a Warming Planet - Challenges and Nutritional Strategies to Mitigate Exertional Heat Stress
Purpose of ReviewClimate change is predicted to increase the frequency and severity of exposure to hot environments. This can impair health, physical...
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Woven coronary artery with acquired etiology: the natural history documented by serial angiography and optical coherence tomography
Woven coronary artery (WCA) is a rare anomaly and its etiology remains speculative. Both congenital and acquired factors are considered to be...
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A Novel Diastolic Doppler Index Less Affected by Aortic Arch Anomalies Co-existing with Coarctation
Severity assessment for coarctation of the aorta (CoA) is challenging due to concomitant morphological anomalies (complex CoA) and inaccurate...
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Psychedelic experiences and long-term spiritual growth: a systematic review
Psychedelic substances, which can occasion mystical experiences, are sometimes used for religious and spiritual reasons. Despite strong links between...