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Ethical Considerations and Equipoise in Cancer Surgery
The changing landscape of cancer surgery requires ongoing consideration of ethical issues to ensure patient-centered care and fair access to...
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An evidence-based screening tool for heart failure with preserved ejection fraction: the HFpEF-ABA score
Heart failure with preserved ejection fraction (HFpEF) is under-recognized in clinical practice. Although a previously developed risk score, termed H 2 ...
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Hippocampal network activity forecasts epileptic seizures
Seizures in people with epilepsy were long thought to occur at random, but recent methods for seizure forecasting enable estimation of the likelihood...
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Super T2-FLAIR mismatch sign: a prognostic imaging biomarker for non-enhancing astrocytoma, IDH-mutant
PurposeThe T2-FLAIR mismatch sign is a highly specific diagnostic imaging biomarker for astrocytoma, IDH-mutant. However, a definitive prognostic...
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Pegylated recombinant human granulocyte colony-stimulating factor for primary prophylaxis of neutropenia in patients with cervical cancer receiving concurrent chemoradiotherapy: a prospective study
BackgroundThis study aimed to investigate the efficacy and safety of pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF)...
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Imaging of sports injuries in adolescents
Musculoskeletal injuries in adolescents tend to occur in particular locations and have distinct characteristics, as they affect an immature skeleton....
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An 18-gene signature of recurrence-associated endothelial cells predicts tumor progression and castration resistance in prostate cancer
BackgroundThe prognostic and therapeutic implications of endothelial cells (ECs) heterogeneity in prostate cancer (PCa) are poorly understood.
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GLP and G9a histone methyltransferases as potential therapeutic targets for lymphoid neoplasms
Histone methyltransferases (HMTs) are enzymes that regulate histone methylation and play an important role in controlling transcription by altering...
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A Modified Floxuridine Reduced-Dose Protocol for Patients with Unresectable Colorectal Liver Metastases Treated with Hepatic Arterial Infusion
BackgroundMost patients treated with the standard dosing protocol (SDP) of hepatic arterial infusion (HAI) floxuridine require dose holds and...
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Indocyanine Green Fluorescence-Guided Laparoscopic Anatomical Segmentectomy of Liver Segment 6: Surgical Strategy and Technical Details
BackgroundBecause of the complex anatomy of the right posterior hepatic pedicle, there have been few reports on standardized laparoscopic portal...
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Unlocking potential: a qualitative exploration guiding the implementation and evaluation of professional role substitution models in healthcare
BackgroundAs role substitution models gain prominence in healthcare, understanding the factors sha** their effectiveness is paramount. This study...
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Rare case of myelodysplastic syndrome with excess blasts 2 develo** after adjuvant chemoradiotherapy for triple-negative breast cancer in a patient with Bloom syndrome
IntroductionBloom syndrome (BS) is a rare autosomal recessive disorder caused by a loss-of-function mutation in the BLM gene encoding an RecQ...
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Presence of Fusobacterium nucleatum in relation to patient survival and an acidic environment in oesophagogastric junction and gastric cancers
BackgroundFusobacterium nucleatum inhabits the oral cavity and affects the progression of gastrointestinal cancer. Our prior findings link F....
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Gaseous pollutants linked to pulmonary diseases: East meets West
Air pollution represents a critical global health challenge, especially in densely populated urban areas of develo** countries such as Pakistan,...
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Enhanced γ-H2AX Foci Frequency and Altered Gene Expression in Participants Exposed to Ionizing Radiation During I-131 Nuclear Medicine Procedures
PurposeIonizing radiation-based technologies are extensively used in the diagnosis and treatment of diseases. While utilizing the technologies,...
