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Knockout Transporter Cell Lines to Assess Substrate Potential Towards Efflux Transporters
P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and multidrug resistance transporter 2 (MRP2) are efflux transporters involved in the...
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A review on the cultivation, bioactive compounds, health-promoting factors and clinical trials of medicinal mushrooms Taiwanofungus camphoratus, Inonotus obliquus and Tropicoporus linteus
Medicinal mushrooms, such as Taiwanofungus camphoratus , Inonotus obliquus , and Tropicoporus linteus , have been used in traditional medicine for...
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Examining temporal changes in model-optimized parameters using longitudinal hemodynamic measurements
BackgroundWe previously applied hemodynamic data to personalize a mathematical model of the circulation expressed as physically interpretable...
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Reactive oxygen species and depolarization the inner mitochondrial membrane under effect of synthetic auxin herbicides in plant cell culture of Arabidopsis thaliana L.
The cytotoxic effect of synthetic analogs of auxins, namely 2.4-D and clopyralid on heterotrophic cell suspension culture of Arabidopsis thaliana ,...
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Propionate production by Bacteroidia gut bacteria and its dependence on substrate concentrations differs among species
BackgroundPropionate is a food preservative and platform chemical, but no biological process competes with current petrochemical production routes...
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Yoda1 pretreated BMSC derived exosomes accelerate osteogenesis by activating phospho-ErK signaling via Yoda1-mediated signal transmission
Segmental bone defects, arising from factors such as trauma, tumor resection, and congenital malformations, present significant clinical challenges...
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An end-to-end approach for single-cell infrared absorption spectroscopy of bacterial inclusion bodies: from AFM-IR measurement to data interpretation of large sample sets
BackgroundInclusion bodies (IBs) are well-known subcellular structures in bacteria where protein aggregates are collected. Various methods have...
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Synthesis, Characterization, Phytochemistry, and Therapeutic Potential of Azadirachta indica Conjugated Silver Nanoparticles: A Comprehensive Study on Antidiabetic and Antioxidant Properties
Nanotechnology has become a major topic of study, particularly in the medical and health domains. Because nanomedicine has a higher recovery rate...
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A Comprehensive on Synthesis and Antimicrobial Evaluation of Substituted-Arylideneamino-5-(5-Chlorobenzofuran-2-yl)-1, 2, 4-Triazole-3-Thiol Derivatives/ Schiff Bases
Schiff bases are well known and popular classes of organic compounds containing imine (R 2 C = NH) group that are widely used as catalysts and...
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Nitrogen fertilisation reduces the contribution of root-derived carbon to mineral-associated organic matter formation at low and high defoliation frequencies in a grassland soil
Background and aimsRhizodeposition is organic matter released by living plant roots that can be transformed by microbes into particulate organic...
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Automatic localization of cochlear implant electrodes using cone beam computed tomography images
BackgroundCochlear implants (CI) are implantable medical devices that enable the perception of sounds and the understanding of speech by electrically...
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Non-destructive Ripeness Detection of Avocados (Persea Americana Mill) using Vision and Tactile Perception Information Fusion Method
Vision (skin color) and tactile (firmness) characteristics of avocado are important characteristics associated with the level of ripeness. Avocados...
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CRISPR/Cas9-mediated genome editing technique to control fall armyworm (Spodoptera frugiperda) in crop plants with special reference to maize
Fall Armyworm imposes a major risk to agricultural losses. Insecticides have historically been used to manage its infestations, but it eventually...
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An Approach to Increase Sustainability in Agricultural Systems; An Agroecological Analysis of the Wheat and Sugar Beet Ecosystems
The goal of this study was to undertake a detailed investigation of the agroecological state of the wheat and sugar beet ecosystems on a local scale....
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Evaluation for the combination of oil palm biomass as co-firing fuel: investigation into ash-related problems
Recognizing the imperative to mitigate carbon emissions in power plants, the availability of palm oil biomass in tropical countries holds significant...
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Optimization of biotransformation processes of Camarosporium laburnicola to improve production yields of potent telomerase activators
BackgroundTelomerase activators are promising agents for the healthy aging process and the treatment/prevention of short telomere-related and...
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Synthesis of two Fluorescent Complexes and Their use as Multifunctional Nanomedicine Carriers for Rhabdomyosarcoma Treatment
This study focuses on the design and synthesis of two novel coordination polymers (CPs), named 1 and 2 , with excellent fluorescent properties. Their...
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An affordable detection system based on RT-LAMP and DNA-nanoprobes for avian metapneumovirus
AbstractAirborne animal viral pathogens can rapidly spread and become a global threat, resulting in substantial socioeconomic and health...
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Genome-wide identification and expression analysis of the SOD gene family under biotic and abiotic stresses in sweet orange
Superoxide dismutase (SOD) protects plants from biotic and abiotic stress-induced reactive oxygen species toxicity and is extensively involved in...