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Article Biomedicine, general Immunology

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  2. Silencing DOCK2 Attenuates Cardiac Fibrosis Following Myocardial Infarction in Mice Via Targeting PI3K/Akt and Wnt/β-Catenin Pathways

    Cardiac fibrosis following myocardial infarction (MI) seriously affects the prognosis and survival rate of patients. This study aimed to determine...

    Guangquan Hu, ** Chen, ... **aojie Ding in Journal of Cardiovascular Translational Research
    Article 11 July 2024

  7. Engineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery – design, characterization, and biological insights

    The current spotlight of cancer therapeutics is shifting towards personalized medicine with the widespread use of monoclonal antibodies (mAbs)....

    Ana M. López-Estévez, Y. Zhang, ... María José Alonso in Nano Research
    Article Open access 11 July 2024

  8. Vascular galectins in tumor angiogenesis and cancer immunity

    Sustained tumor angiogenesis, i.e., the induction and maintenance of blood vessel growth by tumor cells, is one of the hallmarks of cancer. The...

    Victor L. J. L. Thijssen in Seminars in Immunopathology
    Article Open access 11 July 2024

  9. Lactate modulates zygotic genome activation through H3K18 lactylation rather than H3K27 acetylation

    In spite of its essential role in culture media, the precise influence of lactate on early mouse embryonic development remains elusive. Previous...

    Yanhua Zhao, Meiting Zhang, ... Lei Lei in Cellular and Molecular Life Sciences
    Article Open access 11 July 2024

  10. A new approach to prevent radiation-induced xerostomia using intraglandular injection of mitochondria-boosting agents

    Radiotherapy in patients with head and neck cancer fairly leads to xerostomia, profoundly affecting their quality of life. With limited effective...

    Mohammad Farhadi, Pedram Fadavi, ... Farzad Taghizadeh-Hesary in BMC Cancer
    Article Open access 11 July 2024

  11. The ANGPTL4-HIF-1α loop: a critical regulator of renal interstitial fibrosis

    Background

    Renal interstitial fibrosis (RIF) is a progressive, irreversible terminal kidney disease with a poor prognosis and high mortality....

    Yan Li, Shuang Chen, ... Santao Ou in Journal of Translational Medicine
    Article Open access 11 July 2024

  12. Attention-based cross-frequency graph convolutional network for driver fatigue estimation

    Fatigue driving significantly contributes to global vehicle accidents and fatalities, making driver fatigue level estimation crucial....

    Jianpeng An, Qing Cai, ... Zhongke Gao in Cognitive Neurodynamics
    Article 11 July 2024

  15. Exosomes: a review of biologic function, diagnostic and targeted therapy applications, and clinical trials

    Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They mediate the exchange...

    Yi-Fan Chen, Frank Luh, ... Yun Yen in Journal of Biomedical Science
    Article Open access 11 July 2024

  16. A phase III randomized clinical trial comparing laparoscopic radical hysterectomy based on open state with abdominal radical hysterectomy in patients with early-stage cervical cancer

    Background

    Cervical cancer is the fourth most frequently diagnosed cancer and the fourth leading cause of cancer death in women, The standard...

    **n Zhao, Yansong Liu, ... Yulin Shi in Trials
    Article Open access 11 July 2024

  18. Inconsistency of in vitro exsheathment triggers for gastrointestinal nematode parasites of sheep, cattle and deer

    Exsheathment is crucial in the transition from free-living to parasitic phase for most strongyle nematode species. A greater understanding of this...

    Kiliana Bekelaar, Luis Carvalho, ... Dave Leathwick in Parasitology Research
    Article Open access 11 July 2024

  19. Metal and ligand modification modulates the electrocatalytic HER, OER, and ORR activity of 2D conductive metal-organic frameworks

    It is highly desirable to design efficient and stable hydrogen evolution reaction (HER) and oxygen evolution/reduction reaction (OER/ORR)...

    Yanan Zhou, Li Sheng, ... **long Yang in Nano Research
    Article 11 July 2024

  20. Circ_0000069 promotes the development of hepatocellular carcinoma by regulating CCL25

    Background

    Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths globally, influenced by aberrant circRNA expression....

    Junshao Zeng, Yi Feng, ... Yifan Sun in BMC Cancer
    Article Open access 11 July 2024
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