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  1. Breast cancer preventive practices and associated factors among reproductive age women in Wadila District, North East Ethiopia: community based cross-sectional study

    Background

    Cancer is one of the leading causes of morbidity and mortality worldwide. Among all cancer types, breast cancer stands out as the most...

    Zemene Damtie, Niguss Cherie, Melaku Mekonnen Agidew in BMC Cancer
    Article Open access 15 July 2024
  2. Understanding lactate in the development of Hepatitis B virus-related hepatocellular carcinoma

    Hepatitis B Virus (HBV) is a hepatotropic virus that can establish a persistent and chronic infection in humans. Chronic hepatitis B (CHB) infection...

    Sheida Behzadi Sheikhrobat, Shahab Mahmoudvand, ... Somayeh Shokri in Infectious Agents and Cancer
    Article Open access 15 July 2024
  3. A multidisciplinary group-based survivorship intervention for those living with multiple myeloma: a feasibility study

    Background

    While multiple myeloma continues to be an incurable cancer, advances in its understanding and management have led to significantly improved...

    Nora Eilert, Norma-Jean Murphy, ... Janusz Krawczyk in Pilot and Feasibility Studies
    Article Open access 15 July 2024
  4. Interrelationship between thyroid hormones and reduced renal function, a review article

    Background

    Understanding the relationship of thyroid hormones with the development of chronic kidney disease (CKD) has important clinical implications...

    Sadaf Agahi, Atieh Amouzegar, ... Ladan Mehran in Thyroid Research
    Article Open access 15 July 2024
  5. SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study

    A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate...

    Ziming Li, Zhengbo Song, ... Shun Lu in Signal Transduction and Targeted Therapy
    Article Open access 15 July 2024
  6. Map** alternative splicing events in colorectal cancer

    Although aberrant splicing events of genes are closely related to the development and progression of colorectal cancer (CRC), the map** of abnormal...

    Yifeng Zheng, Guoqiang Zhong, ... Mingsong Li in Discover Oncology
    Article Open access 15 July 2024
  7. Lessons from the physiological role of guanosine in neurodegeneration and cancer: Toward a multimodal mechanism of action?

    Neurodegenerative diseases and brain tumours represent important health challenges due to their severe nature and debilitating consequences that...

    Carla Inês Tasca, Mariachiara Zuccarini, ... Francisco Ciruela in Purinergic Signalling
    Article 15 July 2024
  8. Cardiovascular events in CML patients treated with Nilotinib: validation of the HFA-ICOS baseline risk score

    Background

    The therapeutic landscape of chronic myeloid leukaemia (CML) has been transformed by tyrosine kinase inhibitors (TKI). Nilotinib, showed...

    Fiona Fernando, Maria Sol Andres, ... Dragana Milojkovic in Cardio-Oncology
    Article Open access 15 July 2024
  9. Preclinical SPECT and PET: Joint EANM and ESMI procedure guideline for implementing an efficient quality control programme

    The aim of this guideline is to provide recommendations for the implementation of an effective and efficient quality control (QC) programme for SPECT...

    Christian Vanhove, Michel Koole, ... Monique Bernsen in European Journal of Nuclear Medicine and Molecular Imaging
    Article 15 July 2024
  10. Effects of high-intensity interval training on cardiometabolic biomarkers in patients with prostate cancer undergoing active surveillance: a randomized controlled trial

    Purpose

    To report the effects of a 12-week high-intensity interval training (HIIT) program on cardiometabolic biomarkers in patients with prostate...

    Dong-Woo Kang, Catherine J. Field, ... Kerry S. Courneya in Prostate Cancer and Prostatic Diseases
    Article 15 July 2024
  11. Nonadherence to oral cancer chemotherapy in hepatocellular carcinoma: prevalence and predictive factors in Vietnam

    Purpose

    Standard oral cancer chemotherapy (OCT) or targeted therapy (OTT) has expanded the treatment methods for hepatocellular carcinoma (HCC)....

    Thai Doan Ky, Nguyen Thi Loan, ... Mai Thanh Binh in BMC Cancer
    Article Open access 15 July 2024
  12. A Ratiometric Benzimidazole-Based Fluorescent Probe for The Recognition of Phosgene in Solution and Gaseous Phases

    Considering the high toxicity and widespread application of phosgene, there is an urgent need to develop a simple and sensitive method for detecting...

    Pandong Mao, Yufei Song, ... Yuan Wang in Journal of Fluorescence
    Article 15 July 2024
  13. Detection and characterization of autoreactive memory stem T-cells in children with acute immune thrombocytopenia

    Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by an isolated decrease in platelets below 100 × 10 9 /l after...

    Asmaa M. Zahran, Omnia H. El-Badawy, ... Khalid I. Elsayh in Clinical and Experimental Medicine
    Article Open access 15 July 2024
  14. Efficacy and Safety of Salvage-line Nivolumab Monotherapy for Advanced Esophageal Squamous Cell Carcinoma: Comparison of 240 mg Versus 480 mg Doses

    Background

    Nivolumab monotherapy is the standard second-line treatment for advanced esophageal squamous cell carcinoma (ESCC) after failure of...

    Yuko Murashima, Shun Yamamoto, ... Ken Kato in Journal of Gastrointestinal Cancer
    Article Open access 15 July 2024
  15. Evaluating [225Ac]Ac-FAPI-46 for the treatment of soft-tissue sarcoma in mice

    Purpose

    Fibroblast Activation Protein (FAP) is an emerging theranostic target that is highly expressed on cancer-associated fibroblasts and on certain...

    Marco F. Taddio, Suraj Doshi, ... Christine E. Mona in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 15 July 2024
  16. DAP12 interacts with RER1 and is retained in the secretory pathway before assembly with TREM2

    DNAX-activating protein of 12 kDa (DAP12) is a transmembrane adapter protein expressed in lymphoid and myeloid lineage cells. It interacts with...

    Yanxia Liu, Sandra Theil, ... Jochen Walter in Cellular and Molecular Life Sciences
    Article Open access 15 July 2024
  17. TOTEM: a multi-cancer detection and localization approach using circulating tumor DNA methylation markers

    Background

    Detection of cancer and identification of tumor origin at an early stage improve the survival and prognosis of patients. Herein, we...

    Dalin **ong, Tiancheng Han, ... Chunguang Li in BMC Cancer
    Article Open access 15 July 2024
  18. SNCA is a potential therapeutic target for COVID-19 infection in diffuse large B-cell lymphoma patients

    Cuprotosis related genes (CRGs) have been proved to be potential therapeutic targets for coronavirus disease 2019 (COVID-19) and cancer, but their...

    Can Chen, Yun Li, ... Shenxian Qian in Apoptosis
    Article Open access 15 July 2024
  19. Enteroviruses: epidemic potential, challenges and opportunities with vaccines

    Enteroviruses (EVs) are the most prevalent viruses in humans. EVs can cause a range of acute symptoms, from mild common colds to severe systemic...

    Minne Jartti, Malin Flodström-Tullberg, Minna M. Hankaniemi in Journal of Biomedical Science
    Article Open access 15 July 2024
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