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Blood pressure is associated with knee pain severity in middle-aged and elderly individuals with or at risks for osteoarthritis: data from the Osteoarthritis Initiative
BackgroundHypertension is a common comorbidity of osteoarthritis (OA). Joint pain is the main clinical manifestation of OA. Knowledge about the...
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The relationship between the duration and the retraction and atrophy grades in traumatic isolated full-thickness supraspinatus tears in young patients
BackgroundThe study aimed to determine the grade of retraction and atrophy according to the time elapsed in traumatic isolated full-thickness...
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Etiology-specific incidence and mortality of diarrheal diseases in the African region: a systematic review and meta-analysis
BackgroundDiarrheal diseases substantially affect public health impact in low- and middle-income countries (LMIC), particularly in Africa, where...
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Oxidative stress across multiple tissues in house sparrows (Passer domesticus) acclimated to warm, stable cold, and unpredictable cold thermal treatments
With climate change increasing not just mean temperatures but the frequency of cold snaps and heat waves, animals occupying thermally variable areas...
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MICAL1 promotes the proliferation in acute myeloid leukemia and is associated with clinical prognosis and immune infiltration
Acute myeloid leukemia (AML) is one of the most common hematopoietic malignancies that has a poor prognosis and a high rate of relapse. Dysregulated...
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Pd/N-doped carbon dots@dendritic mesoporous silica nanospheres: A highly efficient catalyst for the hydrogenation of 4-nitrophenol
Highly dispersed Pd/N-doped carbon dots (Pd/NCDs) were successfully immobilized in the mesoporous channels of amino-functionalized dendritic...
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Understanding the impact of COVID-19 on antibiotic use in Canadian primary care: a matched-cohort study using EMR data
BackgroundInappropriate or overuse of antibiotic prescribing in primary care highlights an opportunity for antimicrobial stewardship (AMS) programs...
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Pegylated recombinant human granulocyte colony-stimulating factor for primary prophylaxis of neutropenia in patients with cervical cancer receiving concurrent chemoradiotherapy: a prospective study
BackgroundThis study aimed to investigate the efficacy and safety of pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF)...
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The effectiveness of expressive art therapy on infertile women undergoing surgery: study protocol for a randomized controlled trial
BackgroundInfertility produces infertility-related stress in both members of infertile couples, especially for infertile women. Some studies verified...
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Highly Sensitive and Selective Fluorescence and Smartphone-Based Sensor for Detection of Rutin Using Boron Nitrogen Co-doped Graphene Quantum Dots
This research explores the fluorescence properties and photostability of boron nitrogen co-doped graphene quantum dots (BN-GQDs), evaluating their...
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Precise in vivo RNA base editing with a wobble-enhanced circular CLUSTER guide RNA
Recruiting the endogenous editing enzyme adenosine deaminase acting on RNA (ADAR) with tailored guide RNAs for adenosine-to-inosine (A-to-I) RNA base...
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An evidence-based screening tool for heart failure with preserved ejection fraction: the HFpEF-ABA score
Heart failure with preserved ejection fraction (HFpEF) is under-recognized in clinical practice. Although a previously developed risk score, termed H 2 ...
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Hippocampal network activity forecasts epileptic seizures
Seizures in people with epilepsy were long thought to occur at random, but recent methods for seizure forecasting enable estimation of the likelihood...
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Template-independent enzymatic synthesis of RNA oligonucleotides
RNA oligonucleotides have emerged as a powerful therapeutic modality to treat disease, yet current manufacturing methods may not be able to deliver...
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Drug repurposing: a retrospective revolution in breast cancer medicine
Breast cancer is a complex disease involving numerous pathways, making effective treatment quite challenging. Among the current scenario, drug...
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An 18-gene signature of recurrence-associated endothelial cells predicts tumor progression and castration resistance in prostate cancer
BackgroundThe prognostic and therapeutic implications of endothelial cells (ECs) heterogeneity in prostate cancer (PCa) are poorly understood.
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