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Improving predictive performance in e-learning through hybrid 2-tier feature selection and hyper parameter-optimized 3-tier ensemble modeling
The paper presents a new feature selection technique developed in detail here to address improved prediction accuracy not only for the...
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Domain adaptation using AdaBN and AdaIN for high-resolution IVD mesh reconstruction from clinical MRI
PurposeDeep learning has firmly established its dominance in medical imaging applications. However, careful consideration must be exercised when...
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High-Performance Fiber Optic SERS Platform Based on Self-assembly AuNPs on Silver Dendrite Nanostructures Using Laser-Assisted Plasmon-Mediated Method for Toxic Pesticide Detection
In this study, we present the fabrication and demonstrate the high performance of a fiber optic surface-enhanced Raman scattering (SERS) platform...
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The ubiquitin-like protein UBTD1 promotes colorectal cancer progression by stabilizing c-Myc to upregulate glycolysis
Dysfunction of the ubiquitin-proteasome system (UPS) is involved in the pathogenesis of various malignancies including colorectal cancer (CRC)....
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Elemental Diet as a Therapeutic Modality: A Comprehensive Review
Elemental diets have been employed for the management of various diseases for over 50 years, with several mechanisms mediating their beneficial...
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SRGAN-enhanced unsafe operation detection and classification of heavy construction machinery using cascade learning
In the inherently hazardous construction industry, where injuries are frequent, the unsafe operation of heavy construction machinery significantly...
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From yeast screening for suitability as single cell protein to fed-batch cultures
Purpose: Fed-batch cultures have rarely been used in single cell protein (SCP) research. This work evaluated multiple yeast species for suitability...
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How Sure is the Driver? Modelling Drivers’ Confidence in Left-Turn Gap Acceptance Decisions
When a person makes a decision, it is automatically accompanied by a subjective probability judgment of the decision being correct, in other words, a...
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Short and long-term 2100 MHz radiofrequency radiation causes endoplasmic reticulum stress in rat testis
Long-term radiofrequency radiation (RFR) exposure, which adversely affects organisms, deteriorates testicular functions. Misfolding or unfolding...
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Preparation of Microsponge Drug Delivery System (MSDDS) Followed by a Scale-Up Approach
In 1987, Won invented the solid-phase porous microsphere (MS), which stores bioactive compounds in many interconnected voids. Spherical particles...
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Elucidating the therapeutic mechanism of betanin in Alzheimer’s Disease treatment through network pharmacology and bioinformatics analysis
Betanin, a natural compound with anti-inflammatory and antioxidant properties, has shown promise in mitigating Alzheimer’s disease (AD) by reducing...
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Peptides and Wound Healing: From Monomer to Combination
Peptides are a kind of compounds formed by α-amino acids linked together by peptide bonds, which are also intermediate products of protein...
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CRISPR-Cas9-mediated deletion enhancer of MECOM play a tumor suppressor role in ovarian cancer
MDS1 and EVI1 complex locus (MECOM), a transcription factor encoding several variants, has been implicated in progression of ovarian cancer. The...
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Sticky business: the intricacies of acylsugar biosynthesis in the Solanaceae
Plants display tremendous chemical diversity. Like all organisms, they possess a core set of metabolites for growth and development. However, plants...
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Does using artificial intelligence assistance accelerate skill decay and hinder skill development without performers’ awareness?
Artificial intelligence in the workplace is becoming increasingly common. These tools are sometimes used to aid users in performing their task, for...
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Duo photoprotective effect via silica-coated zinc oxide nanoparticles and Vitamin C nanovesicles composites
ObjectiveZinc Oxide nanoparticles (ZnO NPs) are used widely in nowadays personal care products, especially sunscreens, as a protector against UV...
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KKL-35 inhibits growth of Staphylococcus aureus by systematically changing bacterial phenotypes
KKL-35 is a new oxadiazole compound with potent broad-spectrum antibacterial activity against a number of gram-positive and gram-negative bacteria....
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AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans
Dynein complexes are large, multi-unit assemblies involved in many biological processes via their critical roles in protein transport and axoneme...
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Underlying Mechanism of Fluoride Inhibits Colonic Gland Cells Proliferation by Inducing an Inflammation Response
The integrity of colonic gland cells is a prerequisite for normal colonic function and maintenance. To evaluate the underlying injury mechanisms in...
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The meaningfulness gap in AI ethics: a guide on how to think through a complex challenge
Technological outsourcing is increasingly prevalent, with AI systems taking over many tasks once performed by humans. This shift has led to various...