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A dynamic state variable model suggests a stronger effect of age than individual energetic state on reproductive allocation in burying beetles
Evolutionary fitness is determined by how an organism allocates energy, or other limited resources, to reproduction during its lifetime. For...
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Sexually dimorphic oxytocin circuits drive intragroup social conflict and aggression in wild house mice
In nature, both males and females engage in competitive aggressive interactions to resolve social conflicts, yet the behavioral principles guiding...
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Serotonergic psychedelic 5-MeO-DMT alters plasticity-related gene expression and generates anxiolytic effects in stressed mice
Serotonergic psychedelics have potential therapeutic effects in treating anxiety and mood disorders, often after a single dose, and are suggested to...
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Is depression a global brain disorder with topographic dynamic reorganization?
Major depressive disorder (MDD) is characterized by a multitude of psychopathological symptoms including affective, cognitive, perceptual,...
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Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation
Data within biobanks capture broad yet detailed indices of human variation, but biobank-wide insights can be difficult to extract due to complexity...
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Suicide attempts and correlates among in-school adolescents in Benin City, Nigeria
We aim to add to the literature on suicidality in Africa by estimating the prevalence and exploring the behavioural correlates of suicide attempts...
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Striatal projection neurons coexpressing dopamine D1 and D2 receptors modulate the motor function of D1- and D2-SPNs
The role of the striatum in motor control is commonly assumed to be mediated by the two striatal efferent pathways characterized by striatal...
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From movement to motivation: a proposed framework to understand the antidepressant effect of exercise
Depression is the leading cause of disability worldwide, exerting a profound negative impact on quality of life in those who experience it....
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Des-acyl ghrelin reduces alcohol intake and alcohol-induced reward in rodents
The mechanisms contributing to alcohol use disorder (AUD) are complex and the orexigenic peptide ghrelin, which enhances alcohol reward, is implied...
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Neuroimaging and natural language processing-based classification of suicidal thoughts in major depressive disorder
Suicide is a growing public health problem around the world. The most important risk factor for suicide is underlying psychiatric illness, especially...
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The parasubthalamic nucleus refeeding ensemble delays feeding initiation and hastens water drinking
The parasubthalamic nucleus (PSTN) is activated by refeeding after food deprivation and several PSTN subpopulations have been shown to suppress...
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Vitamin D, chronic pain, and depression: linear and non-linear Mendelian randomization analyses
Vitamin D deficiency has been linked to various chronic pain conditions. However, randomized trials of vitamin D supplementation have had mixed...
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Pollen composition and physicochemical properties of honey produced by three stingless bees species from a mesotropical subhumid region in Bolivia
Honey produced by stingless bees has distinct nutritional and physicochemical properties that vary depending on the bee species, floral origin and...
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How does rapid body color change affect the conspicuity of lizards to their predators and conspecifics?
AbstractPredator–prey interactions drive the evolution of prey visual camouflage, but prey species also must remain conspicuous to their conspecifics...
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Relative validity of an intelligent ordering system to estimate dietary intake among university students from a medical school in Shanghai, China
BackgroundDietary assessment methods have limitations in capturing real-time eating behaviour accurately. Equipped with automated...
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Epigenetic signals associated with delirium replicated across four independent cohorts
Delirium is risky and indicates poor outcomes for patients. Therefore, it is crucial to create an effective delirium detection method. However, the...
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Central nervous system-associated macrophages modulate the immune response following stroke in aged mice
Age is a major nonmodifiable risk factor for ischemic stroke. Central nervous system-associated macrophages (CAMs) are resident immune cells located...
