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Synthetic datasets for open software development in rare disease research
BackgroundGlobally, researchers are working on projects aiming to enhance the availability of data for rare disease research. While data sharing...
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Can we Predict Drug Excretion into Saliva? A Systematic Review and Analysis of Physicochemical Properties
Background and ObjectivesSaliva is a patient-friendly matrix for therapeutic drug monitoring (TDM) but is infrequently used in routine care. This is...
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The evolving role of pharmacists in depression care: a sco** review
BackgroundWorldwide, depression is known to contribute significantly to the global burden of disease. Considering pharmacists are among the most...
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Diagnosis and treatment of secondary nephrotic syndrome with rash as the first symptom: a case report
BackgroundMembranous nephropathy (MN) is a common type of nephrotic syndrome (NS) in adults, accounting for about 20–30% of cases. Although secondary...
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The use of point of care gastric ultrasound and anesthesia management in pediatric patients with preoperative fasting non-adherence scheduled for elective surgical procedures: a retrospective study
BackgroundFailure to adhere to perioperative fasting requirements increases aspiration risk and can lead to delay or cancellation of surgery. Point...
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Sodium selenite attenuates inflammatory response and oxidative stress injury by regulating the Nrf2/ARE pathway in contrast-induced acute kidney injury in rats
BackgroundContrast-induced acute kidney injury (CI-AKI) is an acute renal complication that occurs after intravascular contrast agent administration....
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Implementing a no-drain policy for extraperitoneal colorectal anastomosis in a real-life setting: analysis of outcomes and surgeons’ adherence
AimRecent evidence has questioned the usefulness of anastomotic drain (AD) after low anterior resection (LAR). However, the implementation and...
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Ruthenibacterium lactatiformans isolated from a human blood culture: a first report
BackgroundRuthenibacterium lactatiformans, a Gram-stain-negative, rod-shaped, obligate anaerobic bacterium of the Oscillospiraceae family, has not...
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Intracranial vasculopathy: an important organ damage in young adult patients with late-onset Pompe disease
BackgroundLate-onset Pompe disease (LOPD) is mainly characterized by progressive limb-girdle muscle weakness and respiratory impairment, whereas...
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Bridging the Gap: Comparing Patient-Clinician Views on Treatment Goals and Communication in the Management of Atopic Dermatitis Within the Asia–Pacific Region
IntroductionIt remains unclear how patients with atopic dermatitis (AD) and clinicians perceive the level of patient–clinician communication and if...
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Importance of hospital and clinical factors for early mortality in Takotsubo syndrome: Insights from the Swedish Coronary Angiography and Angioplasty Registry
BackgroundTakotsubo syndrome (TTS) is an acute heart failure syndrome with symptoms similar to acute myocardial infarction. TTS is often triggered by...
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Effective strategies for pregnancy and lactation-associated osteoporosis: teriparatide use in focus
IntroductionPregnancy and lactation-associated osteoporosis (PLO) is a rare condition characterized by fragility fractures occurring during late...
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A horizontal and perpendicular interlaminar approach for intrathecal nusinersen injection in patients with spinal muscular atrophy and scoliosis: an observational study
BackgroundLumbar puncture is challenging for patients with scoliosis. Previous ultrasound-assisted techniques for lumbar puncture used the angle of...
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Low fetal fraction and adverse pregnancy outcomes— systematic review of the literature and metanalysis
PurposeWhile cell-free DNA (cfDNA) screening has emerged as a screening modality for common aneuploidies, further research and several publications...
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Treatment of insomnia associated with alcohol and opioid use: a narrative review
Substance use disorders (SUDs) are associated with profound sleep disturbances, including insomnia, sleep fragmentation, and circadian rhythm...
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A novel nomogram for predicting the risk of persistent hyperparathyroidism after kidney transplantation
PurposePersistent hyperparathyroidism (PTHPT) in kidney transplant recipients is associated with bone loss, graft dysfunction and cardiovascular...
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Dirofilariasis presenting as pleural effusion: a rare case report with unusual manifestations and treatment modalities
BackgroundWe present an extremely rare manifestation of dirofilariasis in the pleural cavity. This is the first human pulmonary dirofilariasis...
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Predictors of parent self-monitoring patterns in a family-based behavioral weight loss treatment program
ObjectiveSelf-monitoring dietary intake is a critical component of family-based intensive health behavior and lifestyle treatment for pediatric...
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Differential Expression of mRNA in Peripheral Blood Mononuclear Cells May Predict Postoperative Atrial Fibrillation in Coronary Artery Bypass Surgery Patients
AbstractPostoperative Atrial Fibrillation (POAF) frequently follows Coronary Artery Bypass Grafting (CABG) surgery. This prospective study...