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Impact on Glycemia Risk Index and other metrics in type 1 adult patients switching to Advanced Hybrid Closed-Loop systems: a one-year real-life experience
BackgroundAdvanced Hybrid Closed-Loop system (AHCL) has profoundly changed type 1 diabetes therapy. This study primarily aimed to assess the impact...
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Post-implantation analysis of genomic variations in the progeny from develo** fetus to birth
The analysis of genomic variations in offspring after implantation has been infrequently studied. In this study, we aim to investigate the extent of de...
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FADD regulates adipose inflammation, adipogenesis, and adipocyte survival
Adipose tissue, aside from adipocytes, comprises various abundant immune cells. The accumulation of low-grade chronic inflammation in adipose tissue...
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Development of a novel approach for restoration of the meniscus using silk-elastin in a rabbit meniscus injury model
BackgroundLimited healing potential of the meniscus remains a burden for the successful repair of meniscus injuries in the orthopaedic fields....
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Changes in the anteroposterior position of the femur relative to the tibia impact patient satisfaction in total knee arthroplasty
BackgroundIn this study, we aimed to investigate the preoperative and postoperative anteroposterior position (AP) of the femur relative to the tibia...
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Anticholinergic burden and health-related quality of life among adult patients in a resource-limited setting: a cross-sectional study
BackgroundAnticholinergic medications are now widely acknowledged for their unfavorable risk-to-benefit profile owing to their adverse effects....
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Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genes
BackgroundThe genetic background of cancer remains complex and challenging to integrate. Many somatic mutations within genes are known to cause and...
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Single center assessment of the role of Oakland score among patients admitted for acute lower gastrointestinal bleeding
Background/ObjectivesThe Oakland score was developed to predict safe discharge in patients who present to the emergency department with lower...
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The developmental phenotype of motor delay in extremely preterm infants following early-life respiratory adversity is influenced by brain dysmaturation in the parietal lobe
BackgroundResearch indicates that preterm infants requiring prolonged mechanical ventilation often exhibit suboptimal neurodevelopment at follow-up,...
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The impact of codeine rescheduling on non-opioid analgesic use by people who regularly use codeine: a prospective cohort study
BackgroundCodeine was rescheduled in Australia to prescription only in February 2018. Initial studies reported an increase in population level...
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Impact of medicine shortages on hospital practice: role of a multidisciplinary medicine shortages team
Medicine shortages are an increasing issue, with broad public health implications for patients, health professionals and institutions. Despite...
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Feeding Assistance Skill Score: development and verification of reliability and validity
PurposeFeeding assistance should be safe and improve the assisted individual’s ability to feed, yet objective tools for evaluating these skills are...
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Therapeutic Effect of Melatonin on CCl4-Induced Fibrotic Liver Model by Modulating Oxidative Stress, Inflammation, and TGF-β1 Signaling Pathway in Pinealectomized Rats
The study aimed to determine the CCl 4 -induced liver fibrosis model in pinealectomized rats and biochemically, immunohistochemically, and...
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Estimated Incidence of Hospitalizations Attributable to RSV Infection Among Adults in Ontario, Canada, Between 2013 and 2019
IntroductionAdult respiratory syncytial virus (RSV) burden is underestimated due to non-specific symptoms, limited standard-of-care and delayed...
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Anti-C5 monoclonal antibody treatment showing pathological resolution of complement-mediated atypical hemolytic uremic syndrome: a case report
BackgroundNo reports have shown histological changes before and after anti-C5 monoclonal antibody treatment in patients with atypical hemolytic...
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Time to recovery and predictors among admitted preterm neonates in the neonatal intensive care units of public hospitals of Addis Ababa, Ethiopia, 2021
IntroductionEthiopia implemented measures to reduce preterm mortality, and much is currently being done to avoid preterm death, yet preterm death...
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Isotoosendanin inhibits triple-negative breast cancer metastasis by reducing mitochondrial fission and lamellipodia formation regulated by the Smad2/3-GOT2-MYH9 signaling axis
Triple-negative breast cancer (TNBC) is incurable and prone to widespread metastasis. Therefore, identification of key targets for TNBC progression...
