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Deep source transfer learning for the estimation of internal brain dynamics using scalp EEG
Electroencephalography (EEG) provides high temporal resolution neural data for brain-computer interfacing via noninvasive electrophysiological...
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Efficacy of chemotherapy plus immune checkpoint inhibitors in patients with non-small cell lung cancer who have rare oncogenic driver mutations: a retrospective analysis
BackgroundTargeted therapy is now the standard of care in driver–oncogene-positive non-small cell lung cancer (NSCLC). Its initial clinical effects...
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Ile-Pro-Pro attenuates sympathetic activity and hypertension
Isoleucine-proline-proline (Ile-Pro-Pro, IPP) is a natural food source tripeptide that inhibits angiotensin-converting enzyme (ACE) activity. The aim...
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The infrapatellar fat pad in inflammaging, knee joint health, and osteoarthritis
Osteoarthritis (OA) is the most common form of arthritis and accounts for nearly $140 billion in annual healthcare expenditures only in the United...
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miR-223 accelerates lipid droplets clearance in microglia following spinal cord injury by upregulating ABCA1
BackgroundSpinal cord injury (SCI) is characterized by extensive demyelination and inflammatory responses. Facilitating the clearance of lipid...
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Food security among black breast cancer survivors in Maryland: insights from an online pilot study
PurposeFood security, and reliable access to nutritious food, is essential for maintaining health yet remains elusive for many, including U.S....
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Pure epidural extraosseous cavernous hemangioma with thoracic myelopathy: case report and review of literature
IntroductionPure epidural spinal cavernous hemangiomas are rare, benign vascular tumors that account for approximately 4% of all spinal epidural...
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The association between diet quality indices and oxidative stress biomarkers in male footballers and healthy active controls
ObjectiveThe aim of the present study was the association between the relationship between Dietary Quality Index-International (DQI-I) and Healthy...
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Re-establishing immune tolerance in multiple sclerosis: focusing on novel mechanisms of mesenchymal stem cell regulation of Th17/Treg balance
The T-helper 17 (Th17) cell and regulatory T cell (Treg) axis plays a crucial role in the development of multiple sclerosis (MS), which is regarded...
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Truncated tau interferes with the autophagy and endolysosomal pathway and results in lipid accumulation
The autophagy-lysosomal pathway plays a critical role in the clearance of tau protein aggregates that deposit in the brain in tauopathies, and...
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Differential Expression of mRNA in Peripheral Blood Mononuclear Cells May Predict Postoperative Atrial Fibrillation in Coronary Artery Bypass Surgery Patients
AbstractPostoperative Atrial Fibrillation (POAF) frequently follows Coronary Artery Bypass Grafting (CABG) surgery. This prospective study...
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A new 3D model of L929 fibroblasts microtissues uncovers the effects of Bothrops erythromelas venom and its antivenom
In Brazil, around 80% of snakebites are caused by snakes of the genus Bothrops. A three-dimensional culture model was standardized and used to...
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A mathematical model of a thermoelectric device for intracavity hypothermia
We describe here mathematical modeling of thermophysical processes in a thermoelectric device (TED) for intracavitary hypothermia. The mathematical...
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The role of NAD-dependent deacetylase sirtuin-2 in liver metabolic stress through regulating pyruvate kinase M2 ubiquitination
NAD-dependent deacetylase Sirt2 is involved in mammalian metabolic activities, matching energy demand with energy production and expenditure, and is...
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Clinical characteristics and factors associated with survival rate of patients with non-muscle invasive bladder cancer attending at a Tertiary Hospital in Somalia
BackgroundA few studies regarding the epidemiology and risk factors of Non-muscle Invasive Bladder Cancer (NMIBC) are reported from Sub-Saharan...
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EGFR mutations induce the suppression of CD8+ T cell and anti-PD-1 resistance via ERK1/2-p90RSK-TGF-β axis in non-small cell lung cancer
BackgroundNon-small cell lung cancer (NSCLC) patients with EGFR mutations exhibit an unfavorable response to immune checkpoint inhibitor (ICI)...