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Hypothetical Interventions on Cardiovascular Health Metrics for Abnormal Cognitive Aging: An Application of the Parametric g-formula in the CLHLS Cohort Study with 12 Years Follow-Up
BackgroundAbnormal cognitive aging is closely related to dementia.
ObjectivesThis study aimed to estimate the effect of cardiovascular health (CVH)...
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The Effect of Obstructive Sleep Apnea on Cognition: A Focus on Decision-Making
Purpose of ReviewIn this review, we discuss the impact of Obstructive Sleep Apnea (OSA), a sleep-related breathing disorder characterized by...
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Spinal muscular atrophy caused by compound heterozygous SMN1 mutations: two cases and literature review
Spinal muscular atrophy (SMA) is a rare neuromuscular disease, which is characterized by the degeneration of motor neurons, leading to symmetrical...
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Role of optical coherence tomography as a diagnostic marker for neurodegeneration in epilepsy: a cross-sectional analytical study
BackgroundProgressive neurodegeneration is a common consequence of epilepsy, which has a negative impact on the patient’s quality of life. This study...
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Serum level of sclerostin and vitamin D in children with epilepsy
BackgroundEpileptic children can pose an additional risk of poor bone health; this study aimed to evaluate the influence of anti-seizure medications...
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Psychiatric disorders among females with prolonged infertility with or without in vitro fertilization/intracytoplasmic sperm injection failure: a cross-sectional study
ObjectivesThe present study seeks to deepen understanding of the negative impacts of infertility, with a spotlight on the experiences of Egyptian...
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Bupivacaine pleural effusion mimicking a hemothorax after a thoracoscopic microdiscectomy with epidural anesthesia
PurposePost-operative pain after video-assisted thoracoscopic surgery is often treated using thoracic epidural analgesics or thoracic paravertebral...
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Muscle MRI as a biomarker of disease activity and progression in myotonic dystrophy type 1: a longitudinal study
IntroductionMyotonic dystrophy type 1 (DM1) is an autosomal dominant disease characterized by myotonia and progressive muscular weakness and atrophy....
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Phenotypic and mutational spectrum of 17 Chinese patients with Menkes Disease
BackgroundMenkes Disease (MD) is a fatal X-linked recessive disorder caused by mutations in the ATP7A gene. Severe cases typically die before the age...
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Guideline “Parkinson’s disease” of the German Society of Neurology (Deutsche Gesellschaft für Neurologie): concepts of care
IntroductionIn 2023, the German Society of Neurology published a new guideline on Parkinson’s disease. An important section dealt with PD care...
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Elevated plasma neurofilament light was associated with multi-modal neuroimaging features in Alzheimer’s disease signature regions and predicted future tau deposition
BackgroundNeurofilament Light (NfL) is a biomarker for early neurodegeneration in Alzheimer’s disease (AD). This study aims to examine the...
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Clinical spreading of muscle weakness in amyotrophic lateral sclerosis (ALS): a study in 910 patients
BackgroundNeuroanatomical staging of sporadic amyotrophic lateral sclerosis (ALS) indicates that neurodegeneration may spread corticofugally.
...
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Targeting Neurotransmitter Systems in Bipolar Disorder: A comprehensive Review of novel pharmacological approaches
Purpose of ReviewTo critically assess the efficacy of novel pharmacological interventions in managing manic or hypomanic episodes in adult patients...
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Successful treatment with efgartigimod as an add-on therapy in acute attack of anti-AQP4 antibody-positive NMOSD: a case report
BackgroundNeuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune demyelinating disease characterized by recurrent myelitis and optic...
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Single-centre real-life observational study on mortality and outcomes: decompressive craniectomy and brain death in traumatic brain injury, haemorrhage, and other cerebral diseases
BackgroundDecompressive hemicraniectomy (DHC) is used after severe brain damages with elevated, refractory intracranial pressure (ICP). In a non...
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Plasma alpha B crystallin as potential biomarker for predicting pre-operative seizures in glioma
PurposeGlioma-associated epilepsy affects a significant proportion of glioma patients, contributing to disease progression and diminished survival...
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Universal Prevention of Dementia in Italy: A Document Analysis of the 21 Italian Regional Prevention Plans
BackgroundUp to 40% of dementia cases are theoretically avoidable and population-level interventions (i.e., universal prevention) are a key component...
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No Association Found: Adverse Childhood Experiences and Cognitive Impairment in Older Australian Adults
ObjectiveThis study aimed to investigate the relationship between childhood adversity and cognitive impairment in older adults.
Methods ...
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Radiosurgical thalamotomy for the management of tremors: a systematic review and meta-analysis
Medical treatment for tremors may include beta-blockers, primidone, dopaminergic, and anticholinergic drugs but it frequently leads to...
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Latinx Sexual Minority Women and Substance Use: a Sco** Review and Call to Action
Purpose of ReviewLatinx sexual minority women (LSMW) remain a greatly understudied population, likely due to the intersectional invisibility they...
