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The etiological diagnostic value of metagenomic next-generation sequencing in suspected community-acquired pneumonia
BackgroundThe emergence of metagenomic next-generation sequencing (mNGS) may provide a promising tool for early and comprehensive identification of...
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Evaluating the antibacterial effect of meropenem-loaded chitosan/sodium tripolyphosphate (TPP) nanoparticles on Acinetobacter baumannii isolated from hospitalized patients
BackgroundAcinetobacter baumannii is a health threat due to its antibiotic resistance. Herein, antibiotic susceptibility and its association with...
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Hypertension and immune activation in antiretroviral therapy naïve people living with human immunodeficiency virus
BackgroundThe pathogenesis of hypertension (HTN) in people living with HIV/AIDS (PLHIV) is complex and remains not fully understood. Chronic immune...
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Infection prevention and control of highly infectious pathogens in resource-limited countries: an experience from Marburg viral disease outbreak in Kagera Region - Tanzania
Marburg viral disease (MVD) is a highly infectious disease with a case fatality rate of up to 90%, particularly impacting resource-limited countries...
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Multi-state Markov model for time to treatment changes for HIV/AIDS patients: a retrospective cohort national datasets, Ethiopia
BackgroundVirological failure, drug resistance, toxicities, and other issues make it difficult for ART to maintain long-term sustainability. These...
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Spectrum and antimicrobial resistance in acute exacerbation of chronic obstructive pulmonary disease with pneumonia: a cross-sectional prospective study from Vietnam
BackgroundRespiratory infections have long been recognized as a primary cause of acute exacerbation of chronic obstructive pulmonary disease...
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Association between time to surgery and hospital mortality in patients with community-acquired limb necrotizing fasciitis: an 11-year multicenter retrospective cohort analysis
BackgroundNecrotizing fasciitis (NF) is a rare but potentially life-threatening soft tissue infection. The objective of this study was to assess the...
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Mortality in clostridioides difficile infection among patients hospitalized at the university clinical hospital in Wroclaw, Poland – a 3-year observational study
BackgroundIn the last two decades, a significant increase in the number of Clostridioides difficile infection (CDI) cases has been observed. It is...
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Effect of women empowerment on treatment seeking practice for sexually transmitted infections among women in Ethiopia
BackgroundSexually transmitted infections (STI) are public health problems in Ethiopia. Women have a higher chance of acquiring STI. STI...
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Combined clinical significance of MRI and serum mannose-binding lectin in the prediction of spinal tuberculosis
BackgroundSpinal tuberculosis (STB) is a local manifestation of systemic infection caused by Mycobacterium tuberculosis, accounting for a significant...
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The causal relationship between blood cell indices and 28-day mortality in sepsis: a retrospective study and bidirectional Mendelian randomization analysis
BackgroundDespite emerging evidence linking blood cell indices (BCIs) to sepsis mortality, the inconsistency of observational studies obscures the...
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Hepatitis B virus infection as a risk factor for chronic kidney disease: a systematic review and meta-analysis
BackgroundCurrently, several studies have observed that chronic hepatitis B virus infection is associated with the pathogenesis of kidney disease....
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In vitro investigations on interference of selected probiotic candidates with Campylobacter jejuni adhesion and invasion of primary chicken derived cecal and Caco-2 cells
BackgroundCampylobacter (C.) jejuni is one of the most important bacterial foodborne pathogens worldwide. Probiotics such as Lactobacillus or Bacillus ...
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Model correction of diagnostic coding-based RSV incidence for children 0–4 years in the US
BackgroundAlthough administrative claims data have a high degree of completeness, not all medically attended Respiratory Syncytial Virus-associated...
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Genetic variation of TLR3 gene is associated with the outcome of hepatitis b infection in mauritanian patients: case control study
BackgroundToll-Like receptors (TLRs) play an important role in the immune response during hepatitis B virus (HBV) infection. In this study, we...
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Relationship of neutrophil lymphocyte ratio, monocyte lymphocyte ratio and neutrophil monocyte ratio with treatment response in pulmonary tuberculosis patients during intensive phase treatment
ObjectiveTo determine the relationship of Neutrophil Lymphocyte Ratio (NLR), Monocyte Lymphocyte Ratio (MLR), and Neutrophil Monocyte Ratio (NMR)...
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Fever of unknown origin revealing testicular nocardiosis: a case report and literature review
BackgroundNocardia is an ubiquitous soil organism. As an opportunistic pathogen, inhalation and skin inoculation are the most common routes of...
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T cell-mediated Immune response and correlates of inflammation and their relationship with COVID-19 clinical severity: not an intuitive guess
BackgroundPredictors of the outcome of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection remain to be fully determined. We...
