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Impact of hypoalbuminemia on outcomes following pancreaticoduodenectomy: a NSQIP retrospective cohort analysis of 25,848 patients
BackgroundEfforts to preoperatively risk stratify and optimize patients before pancreaticoduodenectomy continue to improve outcomes. This study aims...
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Physical Activity Interventions Framed by the Health Action Process Approach for Adults with Long-Term Conditions: A Sco** Review
BackgroundInterventions that use the Health Action Process Approach (HAPA) model show promise for increasing PA frequency, duration, and intensity....
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Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches
The causes of depression are complex, and the current diagnosis methods rely solely on psychiatric evaluations with no incorporation of laboratory...
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Transverse versus longitudinal mucosal incision during POEM for esophageal motility disorders: a randomized trial
BackgroundLongitudinal incision is the commonly used incision for entry into the submucosal space during peroral endoscopic myotomy (POEM) for...
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Challenges in the diagnosis and treatment of pure non-gestational uterine choriocarcinoma in a child: a case report
BackgroundDiagnosing non-gestational uterine choriocarcinoma in children is challenging because of its rarity and nonspecific imaging findings....
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Deep transfer learning for detection of breast arterial calcifications on mammograms: a comparative study
IntroductionBreast arterial calcifications (BAC) are common incidental findings on routine mammograms, which have been suggested as a sex-specific...
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YAP/TAZ interacts with RBM39 to confer resistance against indisulam
The Hippo pathway and its downstream effectors, Yes-associated protein/transcriptional coactivator with PDZ-binding motif (YAP/TAZ), are essential...
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Panorama of Odontogenic Tumours and Cystic Lesions of Jaw: A Single Institutional Experience
Odontogenic tumours are relatively rare tumours presenting with varied behaviour ranging from hamartomatous lesion to malignant neoplasm. Majority of...
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Core Set of Patient-Reported Outcome Measures for Measuring Quality of Life in Clinical Obesity Care
PurposeThe focus of measuring success in obesity treatment is shifting from weight loss to patients’ health and quality of life. The objective of...
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Successful management of a delayed presentation of traumatic descending thoracic aorta pseudoaneurysm: a literature review based on a case report
BackgroundBlunt traumatic aortic injury (BTAI) is the second leading cause of death due to traumas in young patients. The primary presentation might...
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HIV1 drug resistance among patients experiencing first-line treatment failure in Ethiopia: protocol for a systematic review and meta-analysis
BackgroundThe emergence of HIV drug resistance presents a substantial challenge. Current antiretroviral treatments, along with current classes, face...
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Synthetic datasets for open software development in rare disease research
BackgroundGlobally, researchers are working on projects aiming to enhance the availability of data for rare disease research. While data sharing...
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Can we Predict Drug Excretion into Saliva? A Systematic Review and Analysis of Physicochemical Properties
Background and ObjectivesSaliva is a patient-friendly matrix for therapeutic drug monitoring (TDM) but is infrequently used in routine care. This is...
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The evolving role of pharmacists in depression care: a sco** review
BackgroundWorldwide, depression is known to contribute significantly to the global burden of disease. Considering pharmacists are among the most...
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Evaluation of postoperative results after a presurgical optimisation programme
BackgroundPresurgical optimisation programmes decrease the risk of postoperative complications, reduce hospital stays and speed up patient recovery....
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Mediating role of gestational weight gain in the relationship between socioeconomic status and preterm birth: a Chinese population-based study
BackgroundThe modifiable mechanisms underlying the association between socioeconomic status (SES) and preterm birth remain unclear. This study aimed...
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Diagnosis and treatment of secondary nephrotic syndrome with rash as the first symptom: a case report
BackgroundMembranous nephropathy (MN) is a common type of nephrotic syndrome (NS) in adults, accounting for about 20–30% of cases. Although secondary...