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Behandlung uroonkologischer Patienten
The treatment of uro-oncological malignancies is becoming increasingly individualized and thus more complex. New data on systemic therapy for...
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Breast-conserving surgery versus modified radical mastectomy in T1-2N3M0 stage breast cancer: a propensity score matching analysis
PurposeBreast-conserving surgery (BCS) plus radiotherapy and mastectomy exhibit highly comparable prognoses for early-stage breast cancer; however,...
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Demographics and Clinical Decision Making in Patients with Germline Moderate Penetrance Non-BRCA Mutations in Breast Cancer Related Genes
BackgroundManagement of pathogenic variants in high penetrance genes related to breast cancer (BC), such as BRCA1 and BRCA2, are well established....
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18F-FDG PET/CT Radiomics-Based Multimodality Fusion Model for Preoperative Individualized Noninvasive Prediction of Peritoneal Metastasis in Advanced Gastric Cancer
PurposeThis study was designed to develop and validate a machine learning-based, multimodality fusion (MMF) model using 18 F-fluorodeoxyglucose (FDG)...
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Low-calorie diets are effective for weight loss in patients undergoing benign upper gastrointestinal surgery: a systematic review and meta-analysis
BackgroundObesity may increase surgical complexity in patients undergoing abdominal surgery by limiting visualization and increasing the risk of...
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Surgical outreach for the Americas: a self-sustainable model for partnership and education
IntroductionIt is estimated that up to 28% of global disease burden is surgical with hernias representing a unique challenge as the only definitive...
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Measurement of the distance between tumor micro-foci and gross tumor in rectal cancer pathological specimens: implication on margin distance of clinical target volume treated with high-dose radiotherapy for rectal cancer
PurposeTo measure the micro-foci distance away from gross tumor and to provide reference to create the clinical target volume (CTV) margin for boost...
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Kardiale Kanalopathien im Kontext hereditärer Arrhythmiesyndrome
Genetic arrhythmia disorders are rare diseases; however, they are a common cause of sudden cardiac death in children, adolescents, and young adults....
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The 2023 Doyne Lecture—a cornea care system: evolution
Blindness and visual impairment affect the quality of life of the individual and their family members. Corneal opacities are a key cause of vision...
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Comparison of inflammatory markers in low-pressure pneumoperitoneum with deep neuromuscular block versus standard pressure pneumoperitoneum among patients undergoing laparoscopic cholecystectomy for gallstone disease: a randomized control trial
BackgroundLow-pressure pneumoperitoneum (LPP) is an attempt to improve laparoscopic surgery. Lower pressure causes lesser inflammation and better...
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The role of multimodality imaging in the selection and management of patients treated with cytoreductive surgery and HIPEC
Cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (HIPEC) is the mainstay of potentially curative surgical...
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Diagnostic accuracy and reliability of CT-based Node-RADS for colon cancer
ObjectiveThe Node-RADS classification was recently published as a classification system to better characterize lymph nodes in oncological imaging....
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Early and late assessment of renal allograft dysfunction using intravoxel incoherent motion (IVIM) and diffusion-weighted imaging (DWI): a prospective study
PurposeTo evaluate the ability of the Intravoxel Incoherent Motion (IVIM) and monoexponentially ADC in renal allograft function in the early and late...
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Contemporary Axillary Surgical Management in Patients with Pathologically Node Positive Disease After Neoadjuvant Chemotherapy: A Survey of Members of the American Society of Breast Surgeons
BackgroundAxillary lymph node dissection (ALND) is increasingly omitted for breast cancer patients with pathologic nodal disease after neoadjuvant...
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Nodal Surgery for Patients ≥ 70 Undergoing Mastectomy for DCIS? Choose Wisely
BackgroundRoutine sentinel lymphadenectomy (SLNB) for early-stage HR+/HER2- breast cancer in women ≥70 is discouraged by Choosing Wisely, but whether...
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The Current Landscape of Clinical Trials for Immunotherapy in Pancreatic Cancer: A State-of-the-Art Review
BackgroundPancreatic cancer remains a lethal malignancy with a 5-year survival rate below 6% and about 500,000 deaths annually worldwide. Pancreatic...
