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Development of a novel approach for restoration of the meniscus using silk-elastin in a rabbit meniscus injury model
BackgroundLimited healing potential of the meniscus remains a burden for the successful repair of meniscus injuries in the orthopaedic fields....
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Changes in the anteroposterior position of the femur relative to the tibia impact patient satisfaction in total knee arthroplasty
BackgroundIn this study, we aimed to investigate the preoperative and postoperative anteroposterior position (AP) of the femur relative to the tibia...
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Anticholinergic burden and health-related quality of life among adult patients in a resource-limited setting: a cross-sectional study
BackgroundAnticholinergic medications are now widely acknowledged for their unfavorable risk-to-benefit profile owing to their adverse effects....
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Single center assessment of the role of Oakland score among patients admitted for acute lower gastrointestinal bleeding
Background/ObjectivesThe Oakland score was developed to predict safe discharge in patients who present to the emergency department with lower...
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Die Deutsche Gesellschaft für Rheumatologie und Klinische Immunologie e. V. (DGRh) und die COVID-19-Pandemie
The pandemic led to a global disruption of public life unprecedented in modern times due to an infectious disease, which certainly caused additional...
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Association of ambient temperature on acute ischemic stroke in Yancheng, China
BackgroundAcute ischemic stroke (AIS) is a major global public health issue. There is limited research on the relationship between ambient...
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Anti-C5 monoclonal antibody treatment showing pathological resolution of complement-mediated atypical hemolytic uremic syndrome: a case report
BackgroundNo reports have shown histological changes before and after anti-C5 monoclonal antibody treatment in patients with atypical hemolytic...
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Time to recovery and predictors among admitted preterm neonates in the neonatal intensive care units of public hospitals of Addis Ababa, Ethiopia, 2021
IntroductionEthiopia implemented measures to reduce preterm mortality, and much is currently being done to avoid preterm death, yet preterm death...
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Evaluation of the effect of trendelenburg position duration on intracranial pressure in laparoscopic hysterectomies using ultrasonographic optic nerve sheath diameter measurements
BackgroundDuring laparoscopic surgery, pneumoperitoneum and Trendelenburg positioning applied to provide better surgical vision can cause many...
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From traditional to transactional: exploration of khat use in Ethiopia through an interpretative phenomenological analysis
Khat, a naturally growing stimulant, has seen a significant increase in both consumption and cultivation in eastern Ethiopia. This reliance on khat...
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ISIS 449884 Injection Add-On to Metformin in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Study
IntroductionISIS 449884, a 2′- O -methoxyethyl antisense oligonucleotide that targets the glucagon receptor (GCGR), has demonstrated an ability to...
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Comparison of clinical characteristics and treatment outcomes between initially diagnosed type 1 and type 2 diabetes mellitus patients presenting with diabetic ketoacidosis
ObjectivePatients with type 1 diabetes (T1DM) and type 2 diabetes (T2DM) can present with diabetic ketoacidosis (DKA) as the first manifestation....
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The impact of codeine rescheduling on non-opioid analgesic use by people who regularly use codeine: a prospective cohort study
BackgroundCodeine was rescheduled in Australia to prescription only in February 2018. Initial studies reported an increase in population level...
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Impact of medicine shortages on hospital practice: role of a multidisciplinary medicine shortages team
Medicine shortages are an increasing issue, with broad public health implications for patients, health professionals and institutions. Despite...
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Predicting pharmaceutical prices. Advances based on purchase-level data and machine learning
BackgroundIncreased costs in the health sector have put considerable strain on the public budgets allocated to pharmaceutical purchases. Faced with...
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Kalanchoe pinnata (Lam.) Pers. Leaf ethanolic extract exerts selective anticancer activity through ROS-induced apoptotic cell death in human cancer cell lines
BackgroundThe leaves of Kalanchoe pinnata (Lam.) Pers. ( K. pinnata ), a succulent plant native to tropical regions, are used as a medicinal...
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A comparison of brown fat tissue related hormone levels in metabolically healthy and unhealthy individuals with obesity
PurposeOne of the key functions of brown adipose tissue is its positive impact on metabolism. This study aimed to examine the potential involvement...
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Importance of hospital and clinical factors for early mortality in Takotsubo syndrome: Insights from the Swedish Coronary Angiography and Angioplasty Registry
BackgroundTakotsubo syndrome (TTS) is an acute heart failure syndrome with symptoms similar to acute myocardial infarction. TTS is often triggered by...
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Challenges in the diagnosis and treatment of pure non-gestational uterine choriocarcinoma in a child: a case report
BackgroundDiagnosing non-gestational uterine choriocarcinoma in children is challenging because of its rarity and nonspecific imaging findings....