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Pediatric shunt failure in a resource limited Lower-Middle Income Country (LMIC) institution in La Paz, Bolivia
BackgroundShunt failure is an undesirable but common occurrence following neurosurgical shunting for pediatric hydrocephalus. Little is known about...
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Personality traits and co-occurrence of depressive symptoms and high BMI: a prospective cohort study
We assess the associations between personality traits and co-occurrence of depressive symptoms and high BMI from adolescence to early adulthood. We...
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Twenty-year changes of adolescent mental health and substance use: a Finnish population-based time-trend study
This time-trend study assesses changes in mental health and substance use among Finnish adolescents from 1998 to 2018. Representative samples of...
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Neurological and Psychiatric Clinical Manifestations of Sjögren Syndrome
Purpose of ReviewSjögren Syndrome is a systemic autoimmune disorder that presents mainly with sicca symptoms, but frequently affects other body...
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Elevated serum kynurenic acid in individuals with first-episode psychosis and insufficient response to antipsychotics
The tryptophan-metabolizing kynurenine pathway (KP) can be activated by enhanced inflammatory responses and has been implicated in the...
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Twenty-Year Trends and Urban–Rural Disparities in Smoking, Alcohol Consumption, and Dual Consumption Among Chinese Older Adults
China is a country with large urban–rural disparities. These disparities have been related to public health issues, including smoking/alcohol...
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Behaviour change interventions to improve physical activity in adults: a systematic review of economic evaluations
BackgroundBehaviour change interventions can result in lasting improvements in physical activity (PA). A broad implementation of behaviour change...
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Assessing the Factors Affecting Recruitment to Child and Adolescent Psychiatry Fellowship Programs
ObjectiveThe objective of this pilot study was to sample early career child and adolescent psychiatrists (EC CAP), Child and Adolescent Psychiatry...
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Decreased DTI-ALPS index in delirium: a preliminary MRI study
PurposeDelirium is linked to brain abnormalities, yet the role of the glymphatic system is not well understood. This study aims to examine...
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The Association of Gabapentin Initiation with Cognitive and Behavioral Changes in Older Adults with Cognitive Impairment: A Retrospective Cohort Study
BackgroundAlthough gabapentin has been increasingly prescribed to older adults, the relation between gabapentin initiation and longer-term...
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Cleavage site-directed antibodies reveal the prion protein in humans is shed by ADAM10 at Y226 and associates with misfolded protein deposits in neurodegenerative diseases
Proteolytic cell surface release (‘shedding’) of the prion protein (PrP), a broadly expressed GPI-anchored glycoprotein, by the metalloprotease...
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“If you’re struggling, you don’t really care” – what affects the physical health of young people on child and adolescent mental health inpatient units? A qualitative study with service users and staff
BackgroundPhysical health inequalities of people with serious mental illness (SMI) have been labelled an international scandal; due to the 15–20-year...
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Neural correlates of depression-related smartphone language use in adolescents
Magnetic resonance imaging has provided pathophysiological insights into adolescent depression but is a relatively inaccessible technology....
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Intolerance of uncertainty and psychological flexibility as predictors of mental health from adolescence to old age
PurposeThe COVID-19 pandemic brought with it significant social, economic and health uncertainties. These were proposed to impact young people more...
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Self-expanding intracranial drug-eluting stent system in patients with symptomatic intracranial atherosclerotic stenosis: initial experience and midterm angiographic follow-up
BackgroundSymptomatic intracranial atherosclerotic stenosis (ICAS) is a major cause of ischemic stroke worldwide. In patients undergoing endovascular...
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Defining tumor growth in vestibular schwannomas: a volumetric inter-observer variability study in contrast-enhanced T1-weighted MRI
PurposeFor patients with vestibular schwannomas (VS), a conservative observational approach is increasingly used. Therefore, the need for accurate...
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Adolescent Lifestyle Behaviour Modification and Mental Health: Longitudinal Changes in Diet, Physical Activity, Sleep, Screen Time, Smoking, and Alcohol Use and Associations with Psychological Distress
This study examines longitudinal behaviour change in six key lifestyle behaviours—sleep, physical activity (PA), sedentary recreational screen time,...
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Sex/gender differences in spontaneous reports to a French Addictovigilance centre
To specify psychoactive substances and related complications observed in spontaneous reports (SRs) in women versus men, we assessed SRs on...