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Surgical outreach for the Americas: a self-sustainable model for partnership and education
IntroductionIt is estimated that up to 28% of global disease burden is surgical with hernias representing a unique challenge as the only definitive...
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Comparison of inflammatory markers in low-pressure pneumoperitoneum with deep neuromuscular block versus standard pressure pneumoperitoneum among patients undergoing laparoscopic cholecystectomy for gallstone disease: a randomized control trial
BackgroundLow-pressure pneumoperitoneum (LPP) is an attempt to improve laparoscopic surgery. Lower pressure causes lesser inflammation and better...
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Kardiale Kanalopathien im Kontext hereditärer Arrhythmiesyndrome
Genetic arrhythmia disorders are rare diseases; however, they are a common cause of sudden cardiac death in children, adolescents, and young adults....
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Construction and validation of a nomogram for predicting survival in elderly patients with severe acute pancreatitis: a retrospective study from a tertiary center
PurposeThere is a lack of adequate models specifically designed for elderly patients with severe acute pancreatitis (SAP) to predict the risk of...
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The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD)-related advanced fibrosis and cirrhosis in the United States population utilizing AGILE 3 + and AGILE 4 scores: analysis of the NHANES 2017–2018 cycle
BackgroundStudies attempted to estimate MASLD-related advanced fibrosis (AF) and cirrhosis (MC) prevalence utilized tests with low positive...
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The Current Landscape of Clinical Trials for Immunotherapy in Pancreatic Cancer: A State-of-the-Art Review
BackgroundPancreatic cancer remains a lethal malignancy with a 5-year survival rate below 6% and about 500,000 deaths annually worldwide. Pancreatic...
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The role of multimodality imaging in the selection and management of patients treated with cytoreductive surgery and HIPEC
Cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (HIPEC) is the mainstay of potentially curative surgical...
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Diagnostic accuracy and reliability of CT-based Node-RADS for colon cancer
ObjectiveThe Node-RADS classification was recently published as a classification system to better characterize lymph nodes in oncological imaging....
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Early and late assessment of renal allograft dysfunction using intravoxel incoherent motion (IVIM) and diffusion-weighted imaging (DWI): a prospective study
PurposeTo evaluate the ability of the Intravoxel Incoherent Motion (IVIM) and monoexponentially ADC in renal allograft function in the early and late...
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Significant increase of emergency hernia operation during COVID
IntroductionDuring the COVID-19 pandemic, elective surgeries including hernia repairs, were postponed, or cancelled completely. However, it has been...
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Internal and external factors affecting the performance score of surgical trainees doing laparoscopic appendectomy: a prospective, observational cohort study in a structured training programme
BackgroundLaparoscopic appendectomy is a common procedure and introduced early in general surgical training. How internal (i.e. surgeon’s experience)...
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Perioperative impact of liver cirrhosis on robotic liver resection for hepatocellular carcinoma: a retrospective cohort study
BackgroundThe safety and efficacy of robotic liver resection (RLR) for patients with hepatocellular carcinoma (HCC) have been reported worldwide....
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Power-law scaling in intratumoral microbiota of colorectal cancer
It has recently been proposed that the study of microbial dynamics in humans may gain insights from island biogeographical theory. Here, we test...
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The C-terminal proline-rich repeats of Enteropathogenic E. coli effector EspF are sufficient for the depletion of tight junction membrane proteins and interactions with early and recycling endosomes
BackgroundEnteropathogenic E. coli (EPEC) causes acute infantile diarrhea accounting for significant morbidity and mortality in develo**...
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Equol: a metabolite of gut microbiota with potential antitumor effects
An increasing number of studies have shown that the consumption of soybeans and soybeans products is beneficial to human health, and the biological...
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