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sciMET-cap: high-throughput single-cell methylation analysis with a reduced sequencing burden
DNA methylation is a key component of the mammalian epigenome, playing a regulatory role in development, disease, and other processes. Robust,...
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A review on the cultivation, bioactive compounds, health-promoting factors and clinical trials of medicinal mushrooms Taiwanofungus camphoratus, Inonotus obliquus and Tropicoporus linteus
Medicinal mushrooms, such as Taiwanofungus camphoratus , Inonotus obliquus , and Tropicoporus linteus , have been used in traditional medicine for...
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TFscope: systematic analysis of the sequence features involved in the binding preferences of transcription factors
Characterizing the binding preferences of transcription factors (TFs) in different cell types and conditions is key to understand how they...
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An affordable detection system based on RT-LAMP and DNA-nanoprobes for avian metapneumovirus
AbstractAirborne animal viral pathogens can rapidly spread and become a global threat, resulting in substantial socioeconomic and health...
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COQ7 splice site variant causing a spastic paraparesis phenotype in siblings
The COQ7 gene is one of the causative genes for primary COQ10 deficiency-related disorders. OMIM-related phenotypes include severe...
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A new standardization for the use of chicken embryo: selection of target from the phage display library and infection
AbstractThe filamentous bacteriophage M13KO7 (M13) is the most used in phage display (PD) technology and, like other phages, has been applied in...
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Enzymatic degradation of polylactic acid (PLA)
AbstractEnvironmental concerns arising from the increasing use of polluting plastics highlight polylactic acid (PLA) as a promising eco-friendly...
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Comparative proteomics in tall fescue to reveal underlying mechanisms for improving Photosystem II thermotolerance during heat stress memory
BackgroundThe escalating impacts of global warming intensify the detrimental effects of heat stress on crop growth and yield. Among the earliest and...
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Delineation of the phenotypes and genotypes of PIK3CA-related overgrowth spectrum in East asians
PIK3CA -related overgrowth spectrum (PROS) is an umbrella term to describe a diverse range of developmental disorders. Research to date has...
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Age-specific composition of milk microbiota in Tibetan sheep and goats
AbstractThis study investigates the dynamic changes in milk nutritional composition and microbial communities in Tibetan sheep and goats during the...
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Quadruplex qPCR for detection and discrimination of C. Coli,C. fetus, and C. Jejuni from other Campylobacter species in chicken and sheep meat
Campylobacter is gram-negative bacteria considered the predominant genera isolated from poultry samples and associated with gastroenteritis. Due to...
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Population dynamics and genetic isolation in the Central Himalayan region: insights from Sikkim population, India
India’s rich diversity encompasses individuals from varied geographical, cultural, and ethnic backgrounds. In the field of population genetics,...
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Population structure and selection signal analysis of indigenous sheep from the southern edge of the Taklamakan Desert
Analyzing the genetic diversity and selection characteristics of sheep (Ovis aries) holds significant value in understanding their environmental...
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Investigation of Rabies virus in wild mammals of the atlantic forest in Rio de Janeiro, Brazil
With the successful control of rabies transmitted by dogs in Brazil, wild animals have played a relevant epidemiological role in the transmission of...
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Role of ERG11 and MDR1 genes in cycloheximide and multidrug resistance in Candida species
Candida species are amongst the commensals of the mucosal surfaces of the human body which include the oral cavity, vagina, and intestinal mucosa....
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Understanding the responses of tillering to 2,4-D isooctyl ester in Setaria viridis L.
BackgroundGreen foxtail [ Setaria viridis (L.)] is one of the most abundant and troublesome annual grass weeds in alfalfa fields in Northeast China....
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Identifying key genes and functionally enriched pathways in acute myeloid leukemia by weighted gene co-expression network analysis
Acute myeloid leukemia (AML) is characterized by the uncontrolled proliferation of myeloid leukemia cells in the bone marrow and other hematopoietic...
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Understanding the role of P-type ATPases in regulating pollen fertility and development in pigeonpea
The P-type ATPase superfamily genes are the cation and phospholipid pumps that transport ions across the membranes by hydrolyzing ATP. They are...
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Circ-IP6K2 suppresses tumor progression by modulating the miR-1292-5p/CAMK2N1 signal in clear cell renal cell carcinoma
Renal cell carcinoma (RCC) is a malignant tumor originating from the epithelial cells of the renal tubules. The clear cell RCC subtype is closely...
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Rapid evolution of promoters from germline-specifically expressed genes including transposon silencing factors
BackgroundThe piRNA pathway in animal gonads functions as an ‘RNA-based immune system’, serving to silence transposable elements and prevent...