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Synthesis, Characterization, Phytochemistry, and Therapeutic Potential of Azadirachta indica Conjugated Silver Nanoparticles: A Comprehensive Study on Antidiabetic and Antioxidant Properties
Nanotechnology has become a major topic of study, particularly in the medical and health domains. Because nanomedicine has a higher recovery rate...
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Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells
Cuproptosis is characterized by the aggregation of lipoylated enzymes of the tricarboxylic acid cycle and subsequent loss of iron-sulfur cluster...
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Beneficial Effect of Synbiotic Combination of Limosilactobacillus fermentum FS-10, Lactiplantibacillus plantarum Lp1-IC and Short-Chain Fructooligosaccharides in Colitis Murine Model
Therapies targeting gut microbiota are being extensively researched for colitis patients. In this study, we have tested the efficacy of indigenously...
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Accuracy of prediction from multi-environment trials for new locations using pedigree information and environmental covariates: the case of sorghum (Sorghum bicolor (L.) Moench) breeding
Key messagesWe investigate a method of extracting and fitting synthetic environmental covariates and pedigree information in multilocation trial data...
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Pathogenesis of cardiovascular diseases: effects of mitochondrial CF6 on endothelial cell function
Cardiovascular disease (CVD) stands as a predominant global cause of morbidity and mortality, necessitating effective and cost-efficient therapies...
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LSPR-based Colorimetric Aptasensor Design for Rapid and Simple Detection of Vibrio cholerae O1
AbstractIn recent years, the prevalence of intestinal diseases, particularly Vibrio cholerae , has been on the rise, leading to numerous epidemics...
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Mutational Improvement of the Lactobacillus delbrueckii subsp. lactis Biopreservation Potential
AbstractThe primary objective of this study was to develop tools and strategies aimed at enhancing the synthesis of hydrogen peroxide in Lactobacillus...
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Biochemical Characterization and Electrochemical Cultivation of Halotolerant Autotrophic Iron-Oxidizing Bacteria Isolated from Electroplating Wastewater Sludge in Japan
AbstractThe aerobic and rod-shaped FO1 strain of iron-oxidizing bacteria was isolated from electroplating wastewater sludge using colloidal silica...
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Unveiling the mechanism of essential oil action against skin pathogens: from ancient wisdom to modern science
Essential oils are among the most well-known phyto-compounds, and since ancient times, they have been utilized in medicine. Over 100 essential oils...
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Proteome profiling, biochemical and histological analysis of diclofenac-induced liver toxicity in Yersinia enterocolitica and Lactobacillus fermentum fed rat model: a comparative analysis
Diclofenac is a hepatotoxic non-steroidal anti-inflammatory drug (NSAID) that affects liver histology and its protein expression levels. Here, we...
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Physiological responses of invasive round goby (Neogobius melanostomus) to environmental stressors across a latitudinal span
Ecosystems worldwide are struggling with increasingly high levels of human-induced stressors, impacting their ecological health at local, regional,...
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Emerging roles of CAR-NK cell therapies in tumor immunotherapy: current status and future directions
Cancer immunotherapy harnesses the body’s immune system to combat malignancies, building upon an understanding of tumor immunosurveillance and immune...
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LINC01133 promotes pancreatic ductal adenocarcinoma epithelial–mesenchymal transition mediated by SPP1 through binding to Arp3
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with limited treatment methods. Long non-coding RNAs (lncRNAs) have been found involved...
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Influence of Suppressor of Cytokine Signaling 1 (SOCS1) Gene Variations on Polycystic Ovary Syndrome
Polycystic ovarian syndrome (PCOS) is associated with low-grade systemic inflammation and an increase in inflammation markers, which are crucial in...
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The E2F family: a ray of dawn in cardiomyopathy
Cardiomyopathies are a group of heterogeneous diseases, characterized by abnormal structure and function of the myocardium. For many years, it has...
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Resolving chaperone-assisted protein folding on the ribosome at the peptide level
Protein folding in vivo begins during synthesis on the ribosome and is modulated by molecular chaperones that engage the nascent polypeptide. How...
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Concomitant Production and Utilization of Thermoacidic Phytases from Pichia kudriavzevii FSMP-Y17 in Broilers Feed
AbstractProduction of phytases from Pichia kudriavzevii FSMP-Y17 yeast was enhanced by optimization of the fermentation variables under submerged...
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Degradation of High-density Polyethylene Mediated by Fungus Talaromyces liani JA2HS
AbstractHigh density polyethylene (HDPE) waste accumulation in the environment is one among the major threats faced globally for the last quarter of...
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Improving the Thermostability and Catalytic Performance of the Bacillus subtilis Chitosanase BsCsn46A via Computational Design
AbstractChitosanase plays a pivotal role in the production of chitooligosaccharide. Nevertheless, there is untapped potential for enhancing both its...
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SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis
Ewing’s sarcoma (ES) represents a rare yet exceedingly aggressive neoplasm that poses a significant health risk to the pediatric and adolescent...
