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Open AccessComparison of natural orifice specimen extraction surgery and conventional laparoscopic-assisted resection in the treatment effects of low rectal cancer
Natural orifice specimen extraction surgery (NOSES) is an intra-abdominal procedure that does not require an auxiliary incision to take a surgical sample from the abdominal wall through the natural orifice, bu...
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Article
Open AccessInitiating Ullmann-like coupling of Br2Py by a semimetal surface
Intensive efforts have been devoted to surface Ullmann-like coupling in recent years, due to its appealing success towards on-surface synthesis of tailor-made nanostructures. While attentions were mostly drawn...
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Article
A stable low-temperature H2-production catalyst by crowding Pt on α-MoC
The water–gas shift (WGS) reaction is an industrially important source of pure hydrogen (H2) at the expense of carbon monoxide and water1,2. This reaction is of interest for fuel-cell applications, but requires W...
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Article
Open AccessAssociation between positive history of essential tremor and disease progression in patients with Parkinson's disease
This study aimed to explore the effect of pre-existing essential tremor (ET) history on the disease progression of Parkinson’s disease (PD). We recruited and followed-up a group of PD patients from March 2009 ...
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Open AccessIn situ tuning of electronic structure of catalysts using controllable hydrogen spillover for enhanced selectivity
In situ tuning of the electronic structure of active sites is a long-standing challenge. Herein, we propose a strategy by controlling the hydrogen spillover distance to in situ tune the electronic structure. T...
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Open AccessIon mobility collision cross-section atlas for known and unknown metabolite annotation in untargeted metabolomics
The metabolome includes not just known but also unknown metabolites; however, metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility – mass spectrometry (IM-MS) has emerged as a ...
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Article
Open AccessGraphitic phosphorus coordinated single Fe atoms for hydrogenative transformations
Single-atom metal-nitrogen-carbon (M-N-C) catalysts have sparked intensive interests, however, the development of an atomically dispersed metal-phosphorus-carbon (M-P-C) catalyst has not been achieved, althoug...
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Article
Open AccessAn intracellular membrane protein GEP1 regulates xanthurenic acid induced gametogenesis of malaria parasites
Gametocytes differentiation to gametes (gametogenesis) within mosquitos is essential for malaria parasite transmission. Both reduction in temperature and mosquito-derived XA or elevated pH are required for tri...
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Article
Open AccessDifferent regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE...
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Article
Open AccessReactant friendly hydrogen evolution interface based on di-anionic MoS2 surface
Engineering the reaction interface to preferentially attract reactants to inner Helmholtz plane is highly desirable for kinetic advancement of most electro-catalysis processes, including hydrogen evolution rea...
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Article
Open AccessManipulating spin polarization of titanium dioxide for efficient photocatalysis
Photocatalysis has been regarded as a promising strategy for hydrogen production and high-value-added chemicals synthesis, in which the activity of photocatalyst depends significantly on their electronic struc...
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Article
Open AccessNLRP6 self-assembles into a linear molecular platform following LPS binding and ATP stimulation
NOD-like receptors (NLRs) localize in the cytosol to recognize intracellular pathogen products and initialize the innate immune response. However, the ligands and ligand specificity of many NLRs remain unclear...
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Open AccessReconsidering the prognostic significance of tumour deposit count in the TNM staging system for colorectal cancer
Although the occurrence of tumour deposits (TDs) without metastatic lymph nodes (mLNs) is classified as “N1c” in the 8th TNM staging system for colorectal cancer (CRC), the prognostic significance of the TD count...
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Open AccessProx1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche
The enteric neurotransmitter acetylcholine governs important intestinal epithelial secretory and immune functions through its actions on epithelial muscarinic Gq-coupled receptors such as M3R. Its role in the ...
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Open AccessPlasma metabolomics of early parenteral nutrition followed with enteral nutrition in pancreatic surgery patients
Nutrition support is essential for surgical patients. Patients undergoing pancreaticoduodenectomy (PD) require tremendous nutrient support but also faced with risks of infection and gastrointestinal complicati...
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Open AccessA comparative study on droplet characteristics and specific charge of ethanol in two small-scale electrospray systems
An investigation on the droplet characteristics of ethanol in small-scale combustors with two different systems was conducted experimentally and theoretically. The classical capillary-mesh electrode arrangemen...
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Article
Open AccessIn situ formation of mononuclear complexes by reaction-induced atomic dispersion of supported noble metal nanoparticles
Supported noble metal nanoclusters and single-metal-site catalysts are inclined to aggregate into particles, driven by the high surface-to-volume ratio. Herein, we report a general method to atomically dispers...
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Article
Open AccessDynamic oxygen adsorption on single-atomic Ruthenium catalyst with high performance for acidic oxygen evolution reaction
Achieving active and stable oxygen evolution reaction (OER) in acid media based on single-atom catalysts is highly promising for cost-effective and sustainable energy supply in proton electrolyte membrane elec...
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Open AccessAnchoring Cu1 species over nanodiamond-graphene for semi-hydrogenation of acetylene
The design of cheap, non-toxic, and earth-abundant transition metal catalysts for selective hydrogenation of alkynes remains a challenge in both industry and academia. Here, we report a new atomically disperse...
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Open AccessA novel technique to prepare a single cell suspension of isolated quiescent human hepatic stellate cells
To explore a simple and easy-to-learn procedure for the isolation of human quiescent hepatic stellate cells (HSCs) that requires no advanced training. Thus reducing costs and increasing efficiency. This protoc...