64,433 Result(s)
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**hu Li
Life Sciences
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Article
Open AccessTRAF6 promotes spinal microglial M1 polarization to aggravate neuropathic pain by activating the c-JUN/NF-kB signaling pathway
The neuropathic pain with complex networks of neuroinflammatory activation severely limits clinical therapeutic research. TNF receptor-associated factor 6 (TRAF6) is associated with multiple inflammatory disea...
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Open AccessIncreased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway
Helicobacter pylori (HP) infection initiates and promotes gastric carcinogenesis. ONECUT2 shows promise for tumor diagnosis, prognosis, and treatment. This study explored ONECUT2’s role and the specific mechanism...
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Novel recycling strategy for distillers’ grains waste: prolonged biochar aging promotes cadmium immobilization and lettuce growth by regulating soil nutrient availability and bacterial composition
Converting distillers’ grains (DGs) into biochar (BC) is sustainable option for waste-recycling, but how different aging times and application rates DG-derived BC (DG-BC) influenced lettuce growth and cadmium ...
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Open AccessBiological impact and therapeutic implication of tumor-associated macrophages in hepatocellular carcinoma
The tumor microenvironment is a complex space comprised of normal, cancer and immune cells. The macrophages are considered as the most abundant immune cells in tumor microenvironment and their function in tumo...
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Open AccessEvaluating local plant species for effective fall armyworm management strategies in Taiwan
The emergence of Spodoptera frugiperda (fall armyworm; FAW) in the world has raised concerns regarding its impact on crop production, particularly on corn and sorghum. While chemical control and Bt crops have bee...
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Open AccessGenetic Dissection of Major Rice QTLs for Strong Culms and Fine Map** of qWS5 for Breeding Application in Transplanted System
Rice is one of the major staples that feeds about one half of the global populations, and it is important to identify the genetic loci for the traits related to yield improvement. Lodging will cause severe yie...
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Open AccessIdentification and functional analysis of long non-coding RNA (lncRNA) and metabolites response to mowing in hulless barley (Hordeum vulgare L. var. nudum hook. f.)
Hulless barley (Hordeum vulgare L. var. nudum Hook. f.) is a significant cereal crop and a substantial source of forage for livestock. Long non-coding RNAs (lncRNAs) and metabolites play crucial roles in the nutr...
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Open AccessStructural basis of tethered agonism and G protein coupling of protease-activated receptors
Protease-activated receptors (PARs) are a unique group within the G protein-coupled receptor superfamily, orchestrating cellular responses to extracellular proteases via enzymatic cleavage, which triggers intr...
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Open AccessCas12a-mediated gene targeting by sequential transformation strategy in Arabidopsis thaliana
Gene targeting (GT) allows precise manipulation of genome sequences, such as knock-ins and sequence substitutions, but GT in seed plants remains a challenging task. Engineered sequence-specific nucleases (SSNs...
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Genetic variation and selection of 10-year-old Eucalyptus camaldulensis based on wind damage index and wood properties
Typhoons are becoming frequent and intense with ongoing climate change, threatening ecological security and healthy forest development in coastal areas. Eucalyptus of a predominant introduced species in southern ...
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Open AccessFertilization regime changes rhizosphere microbial community assembly and interaction in Phoebe bournei plantations
Fertilizer input is one of the effective forest management practices, which improves soil nutrients and microbial community compositions and promotes forest productivity. However, few studies have explored the...
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Restoration of degraded alpine meadows from the perspective of plant–soil feedbacks
Understanding the plant–soil feedbacks (PSFs) of dominant species of alpine meadow under different degradation status could provide insights into sustainable restoration. The direction, strength, and influenci...
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Open AccessCorrection: Mesenchymal stem cell-derived microvesicles improve intestinal barrier function by restoring mitochondrial dynamic balance in sepsis rats
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Open AccessSynthetic macrolides overcoming MLSBK-resistant pathogens
Conventional macrolide-lincosamide-streptogramin B-ketolide (MLSBK) antibiotics are unable to counter the growing challenge of antibiotic resistance that is conferred by the constitutive methylation of rRNA base ...
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Suppressing the virulence factors of Candida auris with baicalein through multifaceted mechanisms
Candida auris, a rapidly spreading multi-drug‐resistant fungus, is causing lethal infections under certain conditions globally. Baicalin (BE), an active ingredient extracted from the dried root of Scutellaria bai...
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High expression of ethylene response factor BcERF98 delays the flowering time of non-heading Chinese cabbage
BcERF98 is induced by ethylene signaling and inhibits the expression of BcFT by interacting with BcNF-YA2 and BcEIP9, thereby inhibiting plant flowering.
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Open AccessDexmedetomidine and argon in combination against ferroptosis through tackling TXNIP-mediated oxidative stress in DCD porcine livers
Graft availability from donation after circulatory death (DCD) is significantly limited by ischaemia reperfusion (IR) injury. Effective strategies to mitigate IR injury in DCD grafts are essential to improve g...
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Perenniality: the tale of three MADS-box genes
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Open AccessIdentification and characterization of a new species of Taxus — Taxus qinlingensis by multiple taxonomic methods
The taxonomy of Taxus Linn. remains controversial due to its continuous phenotypic variation and unstable topology, thus adversely affecting the formulation of scientific conservation strategies for this genus. R...
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Actn2 defects accelerates H9c2 hypertrophy via ERK phosphorylation under chronic stress
In humans, ACTN2 mutations are identified as highly relevant to a range of cardiomyopathies such as DCM and HCM, while their association with sudden cardiac death has been observed in forensic cases. Although ...
