102 Result(s)
within
**-jun Qian
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessParasitic insect-derived miRNAs modulate host development
Parasitic wasps produce several factors including venom, polydnaviruses (PDVs) and specialized wasp cells named teratocytes that benefit the survival of offspring by altering the physiology of hosts. However, ...
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Article
Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin
Cross-species transmission of viruses from wildlife animal reservoirs poses a marked threat to human and animal health 1 . Bats have been recognized as one of the most important reservoirs for emerging v...
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Open AccessComparative Proteomic Profiling and Biomarker Identification of Traditional Chinese Medicine-Based HIV/AIDS Syndromes
Given the challenges in exploring lifelong therapy with little side effect for human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) cases, there is increasing interest in d...
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Open AccessNanodroplet processing platform for deep and quantitative proteome profiling of 10–100 mammalian cells
Nanoscale or single-cell technologies are critical for biomedical applications. However, current mass spectrometry (MS)-based proteomic approaches require samples comprising a minimum of thousands of cells to ...
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Open AccessEthyl-substitutive Thioflavin T as a highly-specific fluorescence probe for detecting G-quadruplex structure
G-quadruplex has attracted considerable attention due to their prevalent distribution in functional genomic regions and transcripts, which can importantly influence biological processes such as regulation of t...
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Open AccessObservation of carrier localization in cubic crystalline Ge2Sb2Te5 by field effect measurement
The tunable disorder of vacancies upon annealing is an important character of crystalline phase-change material Ge2Sb2Te5 (GST). A variety of resistance states caused by different degrees of disorder can lead to ...
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Article
Open AccessLaboratory Study on Disconnection Events in Comets
When comets interacting with solar wind, straight and narrow plasma tails will be often formed. The most remarkable phenomenon of the plasma tails is the disconnection event, in which a plasma tail is uprooted...
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Open AccessMolecular Identification of ten species of stored-product psocids through microarray method based on ITS2 rDNA
Stored-product psocids (Psocoptera: Liposcelididae) are cosmopolitan storage pests that can damage stored products and cause serious economic loss. However, because of the body size (~1 mm) of eggs, nymphs, an...
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Open AccessGenomic comparison of esophageal squamous cell carcinoma and its precursor lesions by multi-region whole-exome sequencing
Esophageal squamous dysplasia is believed to be the precursor lesion of esophageal squamous cell carcinoma (ESCC); however, the genetic evolution from dysplasia to ESCC remains poorly understood. Here, we app...
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Open AccesspGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification
The precise and large-scale identification of intact glycopeptides is a critical step in glycoproteomics. Owing to the complexity of glycosylation, the current overall throughput, data quality and accessibilit...
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Open AccessDirect evidence of correlation between the second harmonic generation anisotropy patterns and the polarization orientation of perovskite ferroelectric
For ferroelectric materials, where the polar state breaks the inversion symmetry, second harmonic generation is a useful tool to prove their ferroelectric properties. However, the correlation between the aniso...
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Open AccessTargeted proteomic assays for quantitation of proteins identified by proteogenomic analysis of ovarian cancer
Mass spectrometry (MS) based targeted proteomic methods such as selected reaction monitoring (SRM) are emerging as a promising tool for verification of candidate proteins in biological and biomedical applicati...
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Open AccessHyperuricemia and clustering of cardiovascular risk factors in the Chinese adult population
Hyperuricemia is common in China and the relevance of hyperuricemia and cardiovascular disease (CVD) risk has been highlighted, but to date there has been rarely nation-wide study in China. Here, we aim to est...
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Article
Open AccessHairy/enhancer of Split Homologue-1 Suppresses Vascular Endothelial Growth Factor-induced Angiogenesis via Downregulation of Osteopontin Expression
Angiogenesis plays a critical role in the progression and vulnerability of atherosclerotic plaques; however, the orchestration of angiogenesis in atherosclerotic plaque formation remains unclear. The results o...
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Open AccessEstablishment of a novel human lymphoblastic cell strain with the long arm of chromosome 11 aberration without MLL rearrangement
At present, all cell strains derived from acute lymphoblastic leukemia (ALL) patients with the long arm of chromosome 11 aberration are accompanied with mixed lineage leukemia (MLL) gene rearrangement. In this st...
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Open AccessUltra-high open-circuit voltage of perovskite solar cells induced by nucleation thermodynamics on rough substrates
To obtain high performance CH3NH3PbI3 perovskite solar cells, it is highly important to realise a high open-circuit voltage. Calculation results based on a modified diode model have indicated that a low bare rati...
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Article
Open AccessProteomic analysis reveals a role of melatonin in promoting cucumber seed germination under high salinity by regulating energy production
Seed germination is a critical and complex process in the plant life cycle. Although previous studies have found that melatonin can promote seed germination under salt stress, the involvement of melatonin in t...
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Open AccessNovel and traditional lipid-related biomarkers and their combinations in predicting coronary severity
We investigated simultaneously traditional and novel lipid indices, alone or in combination, in predicting coronary severity assessed by Gensini score (GS) in 1605 non-lipid-lowering-drug-treated patients unde...
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Open AccessMiR-27a rs895819 is involved in increased atrophic gastritis risk, improved gastric cancer prognosis and negative interaction with Helicobacter pylori
MiR-27a rs895819 is a loop-stem structure single nucleotide polymorphism affecting mature miR-27a function. In this study, we performed a comprehensive analysis about the association of rs895819 with gastric canc...
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Open AccessHOPX hypermethylation promotes metastasis via activating SNAIL transcription in nasopharyngeal carcinoma
Nasopharyngeal carcinoma (NPC) is characterized by a high rate of local invasion and early distant metastasis. Increasing evidence indicates that epigenetic abnormalities play important roles in NPC developmen...
