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14,365 Result(s)
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Article
Open AccessMultiparametric mri-based radiomics nomogram for predicting lymph-vascular space invasion in cervical cancer
To develop and validate a multiparametric magnetic resonance imaging (mpMRI)-based radiomics model for predicting lymph-vascular space invasion (LVSI) of cervical cancer (CC).
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Open AccessAge-standardized incidence, prevalence, and mortality rates of autoimmune diseases in adolescents and young adults (15–39 years): an analysis based on the global burden of disease study 2021
Autoimmune diseases (ADs) present significant health challenges globally, especially among adolescents and young adults (AYAs) due to their unique developmental stages. Comprehensive analyses of their burden a...
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Open AccessGenetic diversity of 1,845 rhesus macaques improves genetic variation interpretation and identifies disease models
Understanding and treating human diseases require valid animal models. Leveraging the genetic diversity in rhesus macaque populations across eight primate centers in the United States, we conduct targeted-sequ...
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Open AccessUnlocking wear resistance in an ultrastrong dual-phase high-entropy alloy by interface-constrained deformation of brittle Laves phases
The pronounced brittleness of hard Laves phase intermetallics is detrimental to their tribological properties at room temperature. In this study, we utilized a heterogeneous structure to engineer an ultrastron...
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Open AccessReformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation
Fully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation and effective translation. Despite some progress, delivery systems are still unable to fully achieve this. Here, we reformu...
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Open AccessInvestigation on the contaminate of hand washing activities on the surface of environmental objects in intensive care unit
To detect the contaminate of faucets in hospitals and the splash during hand washing, and to explore the reasonable layout of hand washing pools. Two faucets with roughly the same spatial layout in the ICU of ...
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Open AccessNon-O blood types are associated with a greater risk of large artery atherosclerosis stroke and dysregulation of cholesterol metabolism: an observational study
Previous research on ABO blood types and stroke has been controversial, predominantly suggesting heightened risk of stroke in non-O blood types. Nonetheless, investigations into the correlation and underlying ...
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Open AccessDecoding the role of DNA methylation in allergic diseases: from pathogenesis to therapy
Allergic diseases, characterized by a broad spectrum of clinical manifestations and symptoms, encompass a significant category of IgE-mediated atopic disorders, including asthma, allergic rhinitis, atopic derm...
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Open AccessAssociations of metabolic changes and polygenic risk scores with cardiovascular outcomes and all-cause mortality across BMI categories: a prospective cohort study
Associations between metabolic status and metabolic changes with the risk of cardiovascular outcomes have been reported. However, the role of genetic susceptibility underlying these associations remains unexpl...
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Open AccessApplication of QPSO-BPSO in fault self-healing of distributed power distribution networks
With the widespread application of distributed power sources in distribution networks, fault self-healing technology has become the key to ensuring the reliability of power systems. The micro-grid ensures syst...
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Open AccessIs face and information availability important in green purchasing among young consumers?
With the growing awareness of environmental issues available across various media platforms, consumers, particularly the younger generation, are more conscious of their consumption and its impact on the enviro...
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Open AccessNitrate pollution deterioration in winter driven by surface ozone increase
Recently, nitrate (NO3–) levels in winter pollution in eastern China have been increasing yearly and have become the main component of PM2.5. The factors contributing to this rise in surface NO3– concentrations r...
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Open AccessCarbon-based nanomaterials cause toxicity by oxidative stress to the liver and brain in Sprague–Dawley rats
Carbon-based nanomaterials have important research significance in various disciplines, such as composite materials, nanoelectronic devices, biosensors, biological imaging, and drug delivery. Recently, the hum...
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Open AccessAnti-hyperuricemia effect of Clerodendranthus spicatus: a molecular biology study combined with metabolomics
Hyperuricemia (HUA), a metabolic disease caused by excessive production or decreased excretion of uric acid (UA), has been reported to be closely associated with a variety of UA transporters. Clerodendranthus spi...
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Open AccessIdentification of a combined hypoxia and lactate metabolism prognostic signature in lung adenocarcinoma
In the tumor microenvironment (TME), a bidirectional relationship exists between hypoxia and lactate metabolism, with each component exerting a reciprocal influence on the other, forming an inextricable link. ...
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Correction to: Successful Immune Reconstitution in a Patient with a TYK2 Deficiency after Allogeneic Stem Cell Transplantation from Unrelated Donors
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Open AccessAuthor Correction: ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice
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Open AccessMulti-omic characterization of allele-specific regulatory variation in hybrid pigs
Hybrid map** is a powerful approach to efficiently identify and characterize genes regulated through mechanisms in cis. In this study, using reciprocal crosses of the phenotypically divergent Duroc and Lulai...
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Open AccessDetectability of intracranial vessel wall atherosclerosis using black-blood spectral CT: a phantom and clinical study
Computed tomography (CT) is the usual modality for diagnosing stroke, but conventional CT angiography reconstructions have limitations.
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Open AccessAlternate levels versus all levels mini-plate fixation in C3-6 cervical laminoplasty: a retrospective comparative study
The purpose of this study is to compare radiological and clinical outcomes between alternate levels (C4 and C6) and all levels mini-plate fixation in C3-6 unilateral open-door laminoplasty.