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142 Result(s)
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Article
Open AccessMicrobiota and metabolites alterations in proximal and distal gastric cancer patients
Globally, gastric cancer is the third most common cancer and the third leading cause of cancer death. Proximal and distal gastric cancers have distinct clinical and biological behaviors. The microbial composit...
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Open AccessFormable porous biochar loaded with La-Fe(hydr)oxides/montmorillonite for efficient removal of phosphorus in wastewater: process and mechanisms
The development of biochar-based granule-like adsorbents suitable for scaled-up application has been attracting increasing attention in the field of water treatment. Herein, a new formable porous granulated bi...
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Open AccessConstruction of machine learning tools to predict threatened miscarriage in the first trimester based on AEA, progesterone and β-hCG in China: a multicentre, observational, case-control study
Endocannabinoid anandamide (AEA), progesterone (P4) and β-human chorionic gonadotrophin (β-hCG) are associated with the threatened miscarriage in the early stage. However, no study has investigated whether com...
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Open AccessVisual acuity, near phoria and accommodation in myopic children using spectacle lenses with aspherical lenslets: results from a randomized clinical trial
To investigate the short- and long-term effects of myopia control spectacle lenses with highly aspherical lenslets (HAL) and slightly aspherical lenslets (SAL) on visual function and visual quality using data ...
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Article
Does antibiotic therapy for chronic endometritis improve clinical outcomes of patients with recurrent implantation failure in subsequent IVF cycles? A systematic review and meta-analysis
This study aims to assess whether antibiotic therapy for chronic endometritis (CE) could improve subsequent IVF outcomes in patients with recurrent implantation failure (RIF).
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Transcriptomic analyses of sweet potato in response to Cd exposure and protective effects of K on Cd-induced physiological alterations
We aimed to understand the molecular mechanism of differential cadmium (Cd) accumulation in two cultivars of sweet potato and to clarify the effects of potassium (K) supply on Cd accumulation. Comparative tran...
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Open AccessComparison of peripheral refraction and higher-order aberrations between orthokeratology and multifocal soft contact lens designed with highly addition
To compare peripheral defocus, higher-order aberrations (HOAs), and contrast visual acuity (CVA) in myopic children wearing orthokeratology (OK) lenses and multifocal soft contact lenses (MSCLs) designed with ...
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Article
Open AccessEndometrial epithelial cells-derived exosomes deliver microRNA-30c to block the BCL9/Wnt/CD44 signaling and inhibit cell invasion and migration in ovarian endometriosis
Endometriosis (EMs) is a benign gynecological disorder showing some tumor-like migratory and invasive phenotypes. This study intended to investigate the role of microRNA-30c (miR-30c) in EMs, which is involved...
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Article
Macrophage mitochondrial fission improves cancer cell phagocytosis induced by therapeutic antibodies and is impaired by glutamine competition
Phagocytosis is required for the optimal efficacy of many approved and promising therapeutic antibodies for various malignancies. However, the factors that determine the response to therapies that rely on phag...
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Article
The use of supercytokines, immunocytokines, engager cytokines, and other synthetic cytokines in immunotherapy
Cytokines exert powerful immunomodulatory effects that are critical to physiology and pathology in humans. The application of natural cytokines in clinical studies has not been clearly established, and there a...
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Article
Open AccessHost miRNAs-microbiota interactions in gastric cancer
It is widely acknowledged that gastric cancer seriously affects the quality of life and survival of patients. The correlation between the microbiota and gastric cancer has attracted extensive attention in rece...
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Article
Preparation of multifunctional wound dressings with composite PVA/PE films
The waterproof and breathable wound dressings have undergone continuous and substantial evolution over time. Polyethene films have been widely used to fabricate waterproof dressing. Electrospun biopolymers ena...
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Article
Motion by mean curvature in interacting particle systems
There are a number of situations in which rescaled interacting particle systems have been shown to converge to a reaction diffusion equation (RDE) with a bistable reaction term, see e.g., Cox et al. (Astérisqu...
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Article
Open AccessA novel genomic classification system of gastric cancer via integrating multidimensional genomic characteristics
Gastric cancer (GC) is one of the leading causes of cancer deaths with high heterogeneity. There is currently a paucity of clinically applicable molecular classification system to guide precise medicine.
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Article
Eosinophil extracellular traps drive asthma progression through neuro-immune signals
Eosinophilic inflammation is a feature of allergic asthma. Despite mounting evidence showing that chromatin filaments released from neutrophils mediate various diseases, the understanding of extracellular DNA ...
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Article
Boron decreases cadmium influx into root cells of Capsicum annuum by altering cell wall components and plasmalemma permeability
Large areas of soil are boron (B) deficient and contaminated with cadmium (Cd) in southern China. The aim of this study was to select the optimal B supply level and elucidate the underlying physiological and b...
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Flexible reconfiguration of functional brain networks as a potential neural mechanism of creativity
Creativity relies on the reorganizing of multimodal information and flexible switching between different modes of thinking, suggesting an association between creativity and the reconfiguration of functional br...
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Article
Enhanced adsorption capacity of tetracycline on tea waste biochar with KHCO3 activation from aqueous solution
Activation is an important pathway that can enhance the adsorption capacity of biochar. In this study, a modified tea waste biochar (MTWBC) was prepared via a two-step pyrolysis approach with KHCO3 activation. Pr...
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Open AccessMelatonin inhibits triple-negative breast cancer progression through the Lnc049808-FUNDC1 pathway
Melatonin has been reported to have tumor-suppressive effects via comprehensive molecular mechanisms, and long non-coding RNAs (lncRNAs) may participate in this process. However, the mechanism by which melaton...
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Open AccessWhole-exome sequencing of alpha-fetoprotein producing gastric carcinoma reveals genomic profile and therapeutic targets
Alpha-fetoprotein producing gastric carcinoma (AFPGC) is a rare and aggressive subtype of gastric cancer. However, little is known about the genomic features of this disease. We perform whole-exome sequencing ...