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1,093 Result(s)
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Article
Open AccessPhosphorylation of FOXK2 at Thr13 and Ser30 by PDK2 sustains glycolysis through a positive feedback manner in ovarian cancer
Ovarian cancer is one of the most common gynecological malignant tumors with insidious onset, strong invasiveness, and poor prognosis. Metabolic alteration, particularly aerobic glycolysis, which is tightly re...
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Dynamic temporal neural patterns based on multichannel LFPs Identify different brain states during anesthesia in pigeons: comparison of three anesthetics
Anesthetic-induced brain activity study is crucial in avian cognitive-, consciousness-, and sleep-related research. However, the neurobiological mechanisms underlying the generation of brain rhythms and specif...
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Design and development of a soluble PDA-Emodin-PVP-MN patch and its anti-obesity effect in rats
Emodin has been proven to have weight-reducing and lipid-lowering effects. In order to make emodin play a better anti-obesity role, we designed and developed an emodin loaded dissolving microneedle patch, in w...
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Identification and Functional Analysis of a de novo IKZF3 Mutation in a Pediatric Patient with Combined Immunodeficiency
AIOLOS, a vital member of the IKAROS protein family, plays a significant role in lymphocyte development and function through DNA binding and protein–protein interactions. Mutations in the IKZF3 gene, which encode...
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Article
Effects of simplified horn ice shapes on flow structures around an airfoil
Ice can change the leading-edge profile of the airfoil and affect the overall aerodynamic performance of the airfoil. Studying the effects of simplified horn ice shapes on the flow field structures can provide...
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Article
Open AccessComprehensive dry eye therapy: overcoming ocular surface barrier and combating inflammation, oxidation, and mitochondrial damage
Dry Eye Disease (DED) is a prevalent multifactorial ocular disease characterized by a vicious cycle of inflammation, oxidative stress, and mitochondrial dysfunction on the ocular surface, all of which lead to ...
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Article
Non-intestinal-type adenocarcinoma of the nasal cavity and paranasal sinuses: an analysis of clinical characteristics and prognosis
Non‑intestinal adenocarcinoma of the nasal cavity and paranasal sinuses (non‑ITAC) is a heterogeneous tumour that has rarely been reported in previous studies. We compared and analysed the symptoms, radiograph...
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Article
Open AccessMedullary sponge kidney with IgA nephropathy: a case report and literature review
Medullary sponge kidney (MSK)is rare in association with glomerulonephritis. We report a patient with medullary sponge kidney, and the kidney biopsy revealed a diagnosis of IgA nephropathy.
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Article
A Knowledge Graph Based Disassembly Sequence Planning For End-of-Life Power Battery
The accurate and efficient intelligent planning of disassembly sequences plays a crucial role in ensuring the high-quality recycling of end-of-life power batteries. However, the solution space obtained by the ...
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Article
Bacillus altitudinis LZP02 improves rice growth by resha** the rhizosphere microbiome
Rhizosphere microorganisms play an important role in promoting plant growth and maintaining soil health. Bacillus altitudinis LZP02 (LZP02) is an efficient plant growth-promoting rhizobacterium that interacts clo...
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Article
Improvement strategy on thermophysical properties of A2B2O7-type rare earth zirconates for thermal barrier coatings applications: A review
The A2B2O7-type rare earth zirconate compounds have been considered as promising candidates for thermal barrier coating (TBC) materials because of their low sintering rate, improved phase stability, and reduced t...
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Article
Open AccessPolarizability matters in enantio-selection
The prevalence of chirality, or, handedness in biological world is a fundamental phenomenon and a characteristic hallmark of life. Thus, understanding the origin of enantio-selection, i.e., the sense and magni...
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Article
Magnetism and electronic properties of ConMoP (n = 1 ~ 5) cluster: a DFT study
Hydrogen has emerged as a promising clean energy carrier, underscoring the imperative need to comprehend its adsorption mechanisms. This study delves into the magnetic and electronic properties of Co-Mo-P clus...
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Article
A metal–organic framework and quantum dot-based ratiometric fluorescent probe for the detection of formaldehyde in food
A green and sensitive ratio fluorescence strategy was proposed for the detection of formaldehyde (FA) in food based on a kind of metal–organic frameworks (MOFs), MIL-53(Fe)-NO2, and nitrogen-doped Ti3C2 MXene qua...
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Article
Open AccessPhase diagram and density of SiO2–H2O fluid across critical conditions
The SiO2–H2O binary system serves as a basis for understanding complex silicate-water systems. In this study, based on limited existing experimental data of solubility, we propose a new thermodynamic model for Si...
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Article
Open AccessThe mitochondria-targeted Kaempferol nanoparticle ameliorates severe acute pancreatitis
Kaempferol (KA), an natural antioxidant of traditional Chinese medicine (TCM), is extensively used as the primary treatment for inflammatory digestive diseases with impaired redox homeostasis. Severe acute pan...
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Article
Correction: Combined effect of falling difficulty and cardiovascular diseases on the risk of all-cause and cardiovascular mortality in older adults: an analysis of the National Health and Nutrition Examination Survey
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Article
Electromechanical coupling dynamic characteristics of electric drive system for electric vehicle
The electromagnetic vibration of the motor and the mechanical vibration of the transmission mechanism are highly coupled in an electric drive system for an electric vehicle, complicating the positioning of the...
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Three-dimensional nasal asymmetry analysis between adolescence and adulthood in postoperative patients with unilateral cleft lip and palate using computed tomography
To investigate the differences of the nasal soft and hard tissue asymmetry in postoperative patients with unilateral cleft lip and palate (UCLP) between adolescence and adulthood, and to explore the correlatio...
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Article
Combined effect of falling difficulty and cardiovascular diseases on the risk of all-cause and cardiovascular mortality in older adults: an analysis of the National Health and Nutrition Examination Survey
To analyze the combined effect of falling difficulty and CVD on the risk of all-cause mortality and CVD mortality in older adults.