51 Result(s)
within
Yu-hong **
Science, Humanities and Social Sciences, multidisciplinary
-
Article
Open AccessGel permeation chromatography process for highly oriented Cs3Cu2I5 nanocrystal film
The emergence of green materials has attracted considerable attention in the field of optoelectronics. Copper-based lead-free metal halide (with a near-unity quantum yield) obtained from Cs3Cu2I5 nanocrystals (NC...
-
Article
Open AccessA top-down strategy for amorphization of hydroxyl compounds for electrocatalytic oxygen evolution
Amorphous materials have attracted increasing attention in diverse fields due to their unique properties, yet their controllable fabrications still remain great challenges. Here, we demonstrate a top-down stra...
-
Article
Open AccessFUT8-mediated aberrant N-glycosylation of B7H3 suppresses the immune response in triple-negative breast cancer
Most patients with triple negative breast cancer (TNBC) do not respond to anti-PD1/PDL1 immunotherapy, indicating the necessity to explore immune checkpoint targets. B7H3 is a highly glycosylated protein. Howe...
-
Article
Open AccessAtlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling
To gain mechanistic insights into the functions and developmental dynamics of tumor-infiltrated immune cells, especially B-lymphocytes, here we combine single-cell RNA-sequencing and antigen receptor lineage a...
-
Article
Open AccessMultispectral camouflage for infrared, visible, lasers and microwave with radiative cooling
Interminable surveillance and reconnaissance through various sophisticated multispectral detectors present threats to military equipment and manpower. However, a combination of detectors operating in different...
-
Article
Open AccessPrediction of drug–target binding affinity using similarity-based convolutional neural network
Identifying novel drug–target interactions (DTIs) plays an important role in drug discovery. Most of the computational methods developed for predicting DTIs use binary classification, whose goal is to determin...
-
Article
Open AccessHost and viral determinants for efficient SARS-CoV-2 infection of the human lung
Understanding the factors that contribute to efficient SARS-CoV-2 infection of human cells may provide insights on SARS-CoV-2 transmissibility and pathogenesis, and reveal targets of intervention. Here, we ana...
-
Article
Open AccessDeep learning method for comet segmentation and comet assay image analysis
Comet assay is a widely used method, especially in the field of genotoxicity, to quantify and measure DNA damage visually at the level of individual cells with high sensitivity and efficiency. Generally, compu...
-
Article
Open AccessPhotovoltaic and flexible deep ultraviolet wavelength detector based on novel β-Ga2O3/muscovite heteroepitaxy
Flexible and self-powered deep ultraviolet (UV) photodetectors are pivotal for next-generation electronic skins to enrich human life quality. The fabrication of epitaxial β-Ga2O3 thin films is challenging on flex...
-
Article
Open AccessAutophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation
Most triple-negative breast cancer (TNBC) patients fail to respond to T cell-mediated immunotherapies. Unfortunately, the molecular determinants are still poorly understood. Breast cancer is the disease geneti...
-
Article
Open AccessAChR antibodies show a complex interaction with human skeletal muscle cells in a transcriptomic study
Acetylcholine receptor (AChR) antibodies are the most important pathogenic marker in patients with myasthenia gravis (MG). The antibodies bind to AChRs on the postsynaptic membrane, and this leads to receptor ...
-
Article
Open AccessBlocking C-Raf alleviated high-dose small-volume radiation-induced epithelial mesenchymal transition in mice lung
The goal of this study was to develop a potential druggable target for lung injury after SABR through the small animal model. Utilising the model, a radiation dose of 70 Gy or 90 Gy was focally (small volume) ...
-
Article
Open AccessPrevalence and risk factors of having antibodies to class I and II human leukocyte antigens in older haploidentical allograft candidates
The effect of donor-specific anti-human leukocyte antigen (HLA) antibodies (DSAs) has been recognized as a factor in graft failure (GF) in patients who underwent umbilical cord blood transplantation (UBT), mat...
-
Article
Open AccessPrognostic model and optimal treatment for patients with stage IVc nasopharyngeal carcinoma at diagnosis
The treatment for patients with stage IVc nasopharyngeal carcinoma (NPC) at diagnosis was still controversial. In this study, we tried to build a prognostic score model and optimize the treatment for the patie...
-
Article
Open AccessInduced Tamoxifen Resistance is Mediated by Increased Methylation of E-Cadherin in Estrogen Receptor-Expressing Breast Cancer Cells
Estrogen receptor-positive breast cancers are treated with tamoxifen, a drug that competitively inhibits the binding of estrogen to its receptor. Resistance to tamoxifen is a major hurdle in effective manageme...
-
Article
Open AccessThe biomass accumulation and nutrient storage of five plant species in an in-situ phytoremediation experiment in the Ningxia irrigation area
Phytoremediation has been widely used and is considered an environmentally friendly and efficient method for mitigating nitrogen (N) and phosphorus (P) loads. However, the technique is rarely employed in the N...
-
Article
Open AccessMulticentre evaluation of Xpert MTB/RIF assay in detecting urinary tract tuberculosis with urine samples
Genitourinary tuberculosis (GUTB) accounts for up to 40% of extrapulmonary tuberculosis cases. Rapid tests for GUTB are urgently needed because it is often associated with delayed health-care seeking, leading ...
-
Article
Open AccessInvolvement of Endothelin 1 in Remote Preconditioning-Induced Cardioprotection through connexin 43 and Akt/GSK-3β Signaling Pathway
The present study was aimed to explore the role of endothelins in remote preconditioning (RP)-induced myocardial protection in ischemia-reperfusion (IR) injury. RP stimulus was given by subjecting hind limb to...
-
Article
Open AccessCharacterization of different bubble formulations for blood-brain barrier opening using a focused ultrasound system with acoustic feedback control
Focused ultrasound combined with bubble-based agents serves as a non-invasive way to open the blood-brain barrier (BBB). Passive acoustic detection was well studied recently to monitor the acoustic emissions i...
-
Article
Open AccessDragonfly wing decorated by gold nanoislands as flexible and stable substrates for surface-enhanced Raman scattering (SERS)
A flexible and stable biomimetic SERS substrate was successfully fabricated by depositing gold (Au) nanoislands on the dragonfly wings (DW) via a simple DC magnetron sputtering system. Characterizations of the...
