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Open AccessTumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysregulation of biglycan
Tumour blood vessels are gateways for distant metastasis. Recent studies have revealed that tumour endothelial cells (TECs) demonstrate distinct phenotypes from their normal counterparts. We have demonstrated ...
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Article
Open AccessComparative genetic analysis of a rare synchronous collision tumor composed of malignant pleural mesothelioma and primary pulmonary adenocarcinoma
Although asbestos acts as a potent carcinogen in pleural mesothelial and pulmonary epithelial cells, it still remains unclear whether asbestos causes specific and characteristic gene alterations in these diffe...
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Article
Tumor angiogenesis—characteristics of tumor endothelial cells
Tumor blood vessels provide nutrition and oxygen to the tumor, resulting in tumor progression. They also act as gatekeepers, inducing tumor metastasis. Thus, targeting tumor blood vessels is an important stra...
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Article
Open AccessBlood stasis may cause thrombosis in the left superior pulmonary vein stump after left upper lobectomy
We previously reported that arterial infarction of vital organs after lobectomy might occur only after left upper lobectomy and be caused by thrombosis in the left superior pulmonary vein stump. We hypothesize...
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Article
Open AccessLeft upper lobectomy can be a risk factor for thrombosis in the pulmonary vein stump
Thrombosis in the left upper pulmonary vein stump after left upper lobectomy is a very rare but important complication because it occurs in the systemic circulation system. We previously made the first ever re...
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Article
Open AccessLimited resection and two-staged lobectomy for non-small cell lung cancer with ground-glass opacity
Lung tumors showing ground-glass opacities on high-resolution computed tomography indicate the presence of inflammation, atypical adenomatous hyperplasia, or localized bronchioloalveolar carcinoma. We adopted ...
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Article
Open AccessVideo-assisted thoracoscopic left lower lobectomy in a patient with lung cancer and a right aortic arch
A right aortic arch is a rare congenital anomaly, with a reported incidence of around 0.1%. A patient with a right aortic arch underwent video-assisted thoracic surgery left lower lobectomy and mediastinal lym...
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Article
Extrapleural hematoma as a complication following thoracotomy for pulmonary lobectomy
Extrapleural hematoma as a complication following thoracic surgery is rare. We report a case of an extrapleural hematoma following pleural lobectomy that resolved completely with nonsurgical treatment. A 63-ye...
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Article
A case of pseudosarcoma associated with type 3 squamous cell carcinoma of the esophagus: Report of a case
A case of a primary esophageal pseudosarcoma associated with an independent type 3 tumor is described herein. A 60-year-old male presented with dysphagia and chest discomfort. A clinical evaluation revealed a ...