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101 Result(s)
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Article
Open AccesspH-switchable nanozyme cascade catalysis: a strategy for spatial–temporal modulation of pathological wound microenvironment to rescue stalled healing in diabetic ulcer
The management of diabetic ulcer (DU) to rescue stalled wound healing remains a paramount clinical challenge due to the spatially and temporally coupled pathological wound microenvironment that features hyperg...
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Article
Identification and fine genetic map** of the golden pod gene (pv-ye) from the snap bean (Phaseolus vulgaris L.)
Using bulked segregant analysis combined with next-generation sequencing, we delimited the pv-ye gene responsible for the golden pod trait of snap bean cultivar A18-1. Sequence analysis identified Phvul.002G00...
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The common occurrence of 2n eggs by lily F1 distant hybrids and its significance on lily breeding: a case of analyzing OT hybrids
It has been reported that F1 LA hybrids could produce a small number of functional 2n eggs regardless of their male sterility, however, there are very little similar phenomena reported in OA, LO, or OT hybrids, t...
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Ultrathin Ni/V-layered double hydroxide nanosheets for efficient visible-light-driven photocatalytic nitrogen reduction to ammonia
Ammonia is important for industrial development and human life. The traditional Haber Bosch method converts nitrogen into ammonia gas at high temperatures and pressures, causing serious pollution and greenhous...
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Article
Schiff-base silver nanocomplexes formation on natural biopolymer coated mesoporous silica contributed to the improved curative effect on infectious microbes
Infectious microbes that spread easily in healthcare facilities remain as the severe threat for the public health, especially among immunocompromised populations. Given the intricate problem of dramatic increa...
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Changes in soil ammonia oxidizers and potential nitrification after clear-cutting of boreal forests in China
The Korean pine and broad-leaved mixed forests are the most typical and complete ecosystem among the global boreal forests, with extremely important ecological functions. However, few studies on the changes of...
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Characterization on gut microbiome of PCOS rats and its further design by shifts in high-fat diet and dihydrotestosterone induction in PCOS rats
Polycystic ovary syndrome (PCOS) is associated with gut microbiota disturbance. Emerging evidence has shown that gut microbiota plays a major role in the development of PCOS. To better understand how the gut m...
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Article
“One-step” characterization platform for pathogenic genetics of Staphylococcus aureus
Staphylococcus aureus (S. aureus) is an important human pathogen causing a variety of life-threatening diseases. In recent years, the health problem caused by S. aureus contaminated food has become a global healt...
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Article
Large valley-polarized state in single-layer NbX2 (X = S, Se): Theoretical prediction
Exploring two-dimensional valleytronic crystals with large valley-polarized state is of considerable importance due to the promising applications in next-generation information related devices. Here, we show f...
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Article
Circular RNA circ_0032821 contributes to oxaliplatin (OXA) resistance of gastric cancer cells by regulating SOX9 via miR-515-5p
Chemoresistance is one of the major obstacles for gastric cancer (GC) treatment. Exosome-mediated transfer of circular RNAs (circRNAs) is associated with the drug-resistance in GC. Circ_0032821 has been report...
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Open AccessIdentification of differentially expressed proteins and clinicopathological significance of HMGB2 in cervical cancer
To investigate the complexity of proteomics in cervical cancer tissues, we used isobaric tags for relative and absolute quantitation (iTRAQ)-based mass spectrometry analysis on a panel of normal cervical tissu...
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A Novel Donor–Acceptor Fluorescent Sensor for Zn2+ with High Selectivity and its Application in Test Paper
A novel donor–acceptor fluorescent sensor was designed and synthesized. The sensor exhibited high selectivity and sensitivity to Zn2+ in acetonitrile solution. When 3.0 equiv. of Zn2+ was added gradually, the emi...
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Article
Open AccessMicroRNA-1179 suppresses the proliferation and enhances vincristine sensitivity of oral cancer cells via induction of apoptosis and modulation of MEK/ERK and PI3K/AKT signalling pathways
The role of miR-1179 in the development of cancer has been proved by different studies. However, the expression profile and role of miR-1179 is yet to be explored in human oral cancer. Consistently, this study...
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Pharmacokinetics of Sodium Selenite in Rat Plasma and Tissues After Intragastric Administration
The purpose of this research is to investigate the absorption, distribution, excretion, and pharmacokinetics of selenite in rats after intragastric administration, and thus illustrate the efficiency of seleniu...
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High-flux simultaneous screening of common foodborne pathogens and their virulent factors
Rapid and sensitive detection techniques for foodborne pathogens are important to the food industry. However, traditional detection methods rely on bacterial culture in combination with biochemical tests, a pr...
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Article
Optimization and Evaluation of the Thermosensitive In Situ and Adhesive Gel for Rectal Delivery of Budesonide
Budesonide is a glucocorticoid for the treatment of ulcerative colitis (UC). The current study aims to develop a thermosensitive in situ and adhesive gel for rectal delivery of budesonide. HPMC K4M was selected a...
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Article
Accurate detection of mosaic variants in sequencing data without matched controls
Detection of mosaic mutations that arise in normal development is challenging, as such mutations are typically present in only a minute fraction of cells and there is no clear matched control for removing germ...
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Article
Autophagy May Be Involved in Fluoride-Induced Learning Impairment in Rats
Fluoride can induce neurotoxicity, but the mechanism is not clear. In this study, we explored the role of autophagy in F−-induced neurotoxicity of Wistar rats. Eighty Wistar rats were randomly divided into four g...
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Effects of phenothiazine and phenoxazine on photophysical properties of coumarin derivatives
Two new coumarin derivatives containing phenothiazine or phenoxazine moiety, 3-(benzo[d]oxazol-2-yl)-7-(10H-phenoxazin-10-yl)coumarin (PXZ-C) and 3-(benzo[d]oxazol-2-yl)-7-(10H-phenothiazin-10-yl)coumarin (PTZ-C)...
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QTL analysis of four yield-related traits for Brassica napus L. in multiple environments
Yield improvement is an important target for rapeseed breeding. Resolving the genetic architecture of yield in Brassica napus, QTL analysis was carried out in a double haploid population derived from a cross betw...