28 Result(s)
within
Walter Stummer
Neurology
Oncology
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Chapter
Surgical Management of Glial Cancers
The value of surgery for low- and high-grade gliomas alike has long been debated due to the lack of randomized controlled data. Recent studies are providing more and more insight into different benefits derive...
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Article
Lack of MGMT promoter hypermethylation in hemangiopericytomas of the central nervous system
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Article
Open AccessProspective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery
Survival of glioblastoma patients has been linked to the completeness of surgical resection. Available data, however, were generated with adjuvant radiotherapy. Data confirming that extensive cytoreduction rem...
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Article
Glioblastoma multiforme of the elderly: the prognostic effect of resection on survival
According to recent developments the best treatment options for glioblastoma (GBM) consist in maximum safe resection and additional adjuvant treatment with radiotherapy (RT) and alkylating chemotherapy (CHX)....
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Article
Favorable outcome in the elderly cohort treated by concomitant temozolomide radiochemotherapy in a multicentric phase II safety study of 5-ALA
The primary objective of this augmental, prospective, uncontrolled phase II multicentre trial was to assess adverse events (AE) associated with malignant glioma resection using 5-aminolevulinic (5-ALA). During...
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Article
MGMT promoter methylation status in anaplastic meningiomas
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Article
Long-sustaining response in a patient with non-resectable, distant recurrence of glioblastoma multiforme treated by interstitial photodynamic therapy using 5-ALA: case report
Glioblastoma multiforme continues to be a devastating disease despite modest improvements in survival achieved at present, and there is an urgent need for innovative treatment concepts. Five-aminolevulinic aci...
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Article
Acute morphological sequelae of photodynamic therapy with 5-aminolevulinic acid in the C6 spheroid model
Aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) may represent a treatment option for malignant brain tumors. We used a three-dimensional cell culture system, the C6 glioma spheroid model, to stud...
