46 Result(s)

Article

Author Correction: Development and clinical deployment of a smartphone-based visual field deep learning system for glaucoma detection

Fei Li, Di** Song, Han Chen, Jian **ong, **ngyi Li, Hua Zhong… in npj Digital Medicine (2022)

Article

YinQiSanHuang Jiedu decoction for the treatment of hepatitis B-related compensated liver cirrhosis: study protocol for a multi-center randomized controlled trial

Hepatitis B-related compensated liver cirrhosis is related to a higher risk of hepatocellular carcinoma, and antiviral therapy is the preferred method. As the pathological mechanisms of liver fibrosis are comp...

Qing-Juan Wu, Wen-Liang Lv, Juan-Mei Li, Ting-Ting Zhang, Wen-Hui Zhou… in Trials (2021)

Article

One-year follow-up of chest CT findings in patients after SARS-CoV-2 infection

Knowledge about the 1-year outcome of COVID-19 is limited. The aim of this study was to follow-up and evaluate lung abnormalities on serial computed tomography (CT) scans in patients with COVID-19 after hospit...

Yanfei Chen, Cheng Ding, Ling Yu, Wanru Guo, Xuewen Feng, Liang Yu… in BMC Medicine (2021)

Article

Gestational diabetes mellitus is associated with the neonatal gut microbiota and metabolome

Gestational diabetes mellitus (GDM) is a metabolic disease that occurs in pregnant women and increases the risk for the development of diabetes. The relationship between GDM and meconium microbiota and metabol...

Ting Chen, Yufeng Qin, Minjian Chen, Yuqing Zhang, Xu Wang, Tianyu Dong… in BMC Medicine (2021)

Article

Dietary fruit and vegetable intake, gut microbiota, and type 2 diabetes: results from two large human cohort studies

Little is known about the inter-relationship among fruit and vegetable intake, gut microbiota and metabolites, and type 2 diabetes (T2D) in human prospective cohort study. The aim of the present study was to i...

Zengliang Jiang, Ting-yu Sun, Yan He, Wanglong Gou, Luo-shi-yuan Zuo… in BMC Medicine (2020)

Article

Development and clinical deployment of a smartphone-based visual field deep learning system for glaucoma detection

By 2040, ~100 million people will have glaucoma. To date, there are a lack of high-efficiency glaucoma diagnostic tools based on visual fields (VFs). Herein, we develop and evaluate the performance of ‘iGlauco...

Fei Li, Di** Song, Han Chen, Jian **ong, **ngyi Li, Hua Zhong… in npj Digital Medicine (2020)

Article

Efficacy and safety of YinQiSanHuang-antiviral decoction in chronic hepatitis B: study protocol for a randomized, placebo-controlled, double-blinded trial

Chronic hepatitis B (CHB) is a global public health problem. Antiviral therapy is the primary treatment. Studies have shown that a combined therapy of traditional Chinese medicine (TCM) and conventional antivi...

Qing-Juan Wu, Wen-Liang Lv, Juan-Mei Li, Ting-Ting Zhang, Wen-hui Zhou… in Trials (2020)

Article

CT-based radiomics scores predict response to neoadjuvant chemotherapy and survival in patients with gastric cancer

Neoadjuvant chemotherapy is a promising treatment option for potential resectable gastric cancer, but patients’ responses vary. We aimed to develop and validate a radiomics score (rad_score) to predict treatme...

Kai-Yu Sun, Hang-Tong Hu, Shu-Ling Chen, **-Ning Ye, Guang-Hua Li… in BMC Cancer (2020)

Article

Effect of lymph node dissection on stage-specific survival in patients with upper urinary tract urothelial carcinoma treated with nephroureterectomy

We aimed to estimate the stage-specific impact of lymph node dissection (LND) on survival for upper urinary tract urothelial carcinoma (UTUC) patients treated with nephroureterectomy (NU).

Ting-Shuai Zhai, Liang **, Zhen Zhou, **ang Liu, Huan Liu, Wei Chen… in BMC Cancer (2019)

Article

ROS1-ADGRG6: a case report of a novel ROS1 oncogenic fusion variant in lung adenocarcinoma and the response to crizotinib

ROS1 rearrangements are validated drivers in lung cancer, which have been identified in a small subset (1–2%) of patients with non-small cell lung cancer (NSCLC). To date, 18 fusion genes of ROS1 have been identi...

Shuguang Xu, Wenxian Wang, Chunwei Xu, **ngliang Li, Junhui Ye, Youcai Zhu… in BMC Cancer (2019)

Article

An enrichment method to increase cell-free fetal DNA fraction and significantly reduce false negatives and test failures for non-invasive prenatal screening: a feasibility study

Noninvasive prenatal screening (NIPS) based on cell-free fetal DNA (cffDNA) has rapidly been applied into clinic. However, the reliability of this method largely depends on the concentration of cffDNA in the m...

** Hu, Dong Liang, Yangyi Chen, Ying Lin… in Journal of Translational Medicine (2019)

Article

TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway

Mesenchymal stromal cells (MSCs) were originally characterized by the ability to differentiate into different mesenchymal lineages in vitro, and their immunomodulatory and trophic functions have recently arous...

Ya-nan Bie, Peng Gu, Yu-ting Chen, **ao-xu Zhou… in Journal of Translational Medicine (2019)

Article

The role of EGFR mutation as a prognostic factor in survival after diagnosis of brain metastasis in non-small cell lung cancer: a systematic review and meta-analysis

The brain is a common site for metastasis in non-small-cell lung cancer (NSCLC). This study was designed to evaluate the relationship between the mutational of the epidermal growth factor receptor (EGFR) and o...

Wen-Ya Li, Ting-Ting Zhao, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu… in BMC Cancer (2019)

Article

Selective serotonin reuptake inhibitor use during early pregnancy and congenital malformations: a systematic review and meta-analysis of cohort studies of more than 9 million births

In 2005, the FDA cautioned that exposure to paroxetine, a selective serotonin reuptake inhibitor (SSRI), during the first trimester of pregnancy may increase the risk of cardiac malformations. Since then, the ...

Shan-Yan Gao, Qi-Jun Wu, Ce Sun, Tie-Ning Zhang, Zi-Qi Shen, Cai-**a Liu… in BMC Medicine (2018)

Article

Long non-coding RNA RUNXOR accelerates MDSC-mediated immunosuppression in lung cancer

RUNX1 overlap** RNA (RUNXOR) is a long non-coding RNA that has been indicated as a key regulator in the development of myeloid cells by targeting runt-related transcription factor 1 (RUNX1). Myeloid-derived ...

**nyu Tian, Jie Ma, Ting Wang, Jie Tian, Yu Zheng, Rongrong Peng… in BMC Cancer (2018)

Article

Clinical effect of selective interventional therapy on sub-acute ST-segment elevation myocardial infarction under the guidance of fractional flow reserve and coronary arteriography

This study aims to compare the clinical effects of selective interventional therapy (PCI) under the guidance of fractional flow reserve (FFR) and coronary arteriography.

Bing-Jian Wang, ** Geng, Qian-Jun Li, Ting-Ting Hu… in European Journal of Medical Research (2018)

Article

Effect of neoadjuvant chemotherapy in patients with gastric cancer: a PRISMA-compliant systematic review and meta-analysis

Neoadjuvant chemotherapy (NAC) is extensively used in the treatment of patients with gastric cancer (GC), particularly in high risk, advanced gastric cancer. Previous trials testing the efficacy of NAC have re...

Zhi-Feng Miao, **ng-Yu Liu, Zhen-Ning Wang, Ting-Ting Zhao, Ying-Ying Xu… in BMC Cancer (2018)

Article

A prediction model for lymph node metastases using pathologic features in patients intraoperatively diagnosed as stage I non-small cell lung cancer

There is little information on which pattern should be chosen to perform lymph node dissection for stage I non-small-cell lung cancer. This study aimed to develop a model for predicting lymph node metastasis u...

Fei Zhao, Yue Zhou, Peng-Fei Ge, Chen-Jun Huang, Yue Yu, Jun Li, Yun-Gang Sun… in BMC Cancer (2017)

Article

Step-up fecal microbiota transplantation strategy: a pilot study for steroid-dependent ulcerative colitis

The strategy of using fecal microbiota transplantation (FMT) for refractory ulcerative colitis (UC) remains unclear if single FMT failed to induce remission. This study aimed to evaluate the efficacy and safet...

Bota Cui, Pan Li, Lijuan Xu, Youquan Zhao… in Journal of Translational Medicine (2015)

Article

Severe disturbance of glucose metabolism in peripheral blood mononuclear cells of schizophrenia patients: a targeted metabolomic study

Schizophrenia is a widespread and debilitating mental disorder. However, the underlying molecular mechanism of schizophrenia remains largely unknown and no objective laboratory tests are available to diagnose ...

Mei-Ling Liu, **ao-Tong Zhang, **ang-Yu Du, Zheng Fang… in Journal of Translational Medicine (2015)