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Article
ScRNA-seq of gastric cancer tissues reveals differences in the immune microenvironment of primary tumors and metastases
Gastric carcinoma (GC) is regarded as one of the deadliest cancer characterized by diversity and haste metastasis and suffers limited understanding of the spatial variation between primary and metastatic GC tu...
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Article
Online active vibration control for the magnetic suspension rotor using least mean square and polynomial fitting
Magnetic bearings are widely used in fields such as fluid machinery, aerospace, and marine vessels due to their properties of non-mechanical contact. Due to errors in manufacturing and assembly, unbalanced for...
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Article
Designing semiconductor materials and devices in the post-Moore era by tackling computational challenges with data-driven strategies
In the post-Moore’s law era, the progress of electronics relies on discovering superior semiconductor materials and optimizing device fabrication. Computational methods, augmented by emerging data-driven strat...
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Article
The effect of gonadotropin-inhibitory hormone on steroidogenesis and spermatogenesis by acting through the hypothalamic–pituitary–testis axis in mice
Gonadotropin inhibitory hormone (GnIH) is essential for regulating the reproduction of mammals and inhibiting testicular activities in mice. This study aimed to explore the mechanism of GnIH on spermatogenesis...
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Article
Open AccessGroup IV topological quantum alloy and the role of short-range order: the case of Ge-rich Ge1–xPbx
Despite the explosion of interest in topological materials over the last decades, their applications remain limited due to challenges in growth and incorporation with today’s microelectronics. As a potential b...
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Article
Open AccessThe discovery of regional neurotoxicity-associated metabolic alterations induced by carbon quantum dots in brain of mice using a spatial metabolomics analysis
Recently, carbon quantum dots (CQDs) have been widely used in various fields, especially in the diagnosis and therapy of neurological disorders, due to their excellent prospects. However, the associated inevit...
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Article
Accurate atomic scanning transmission electron microscopy analysis enabled by deep learning
Currently, the machine learning (ML)-based scanning transmission electron microscopy (STEM) analysis is limited in the simulative stage, its application in experimental STEM is needed but challenging. Herein, ...
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Article
Associations of slee** patterns and isotemporal substitution of other behavior with the prevalence of CKD in Chinese adults
Studies have found a U-shaped relationship between sleep duration and chronic kidney disease (CKD) risk, but limited research evaluated the association of reallocating excessive sleep to other behavior with CK...
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Article
Research on the selection of cognitive diagnosis model from the perspective of experts
As a new generation of assessment theory, Cognitive Diagnostic Assessment (CDA) has unique advantages in diagnosing students' personalized information. Cognitive diagnostic models (CDMs) are the core of CDA, s...
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Article
QTL analysis related to rice appearance quality and rice food quality trait using high-density SNP genetic map
Rice is one of the major crops in the world. In the twenty-first century, due to the development and popularity of Japanese food culture, the consumption of rice increased dramatically not only in Asia but als...
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Article
Open AccessRETRACTED ARTICLE: Metal free cross-dehydrogenative N-N coupling of primary amides with Lewis basic amines
Hydrazides, N-N containing structural motifs, are important due to their presence in a wide variety of biologically significant compounds. While the homo N-N coupling of two NH moieties to form the hydrazide N...
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Article
Open AccessThe FBXW7-binding sites on FAM83D are potential targets for cancer therapy
Increasing evidence shows the oncogenic function of FAM83D in human cancer, but how FAM83D exerts its oncogenic function remains largely unclear. Here, we investigated the importance of FAM83D/FBXW7 interactio...
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Article
Osteocyte-derived sclerostin impairs cognitive function during ageing and Alzheimer’s disease progression
Ageing increases susceptibility to neurodegenerative disorders, such as Alzheimer’s disease (AD). Serum levels of sclerostin, an osteocyte-derived Wnt–β-catenin signalling antagonist, increase with age and inh...
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Article
Open AccessRelationship between circadian eating behavior (daily eating frequency and nighttime fasting duration) and cardiovascular mortality
Knowledge regarding the health impacts of daily eating frequency (DEF) and nighttime fasting duration (NFD) on mortality is very limited.
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Article
Open AccessMetabolomic machine learning predictor for diagnosis and prognosis of gastric cancer
Gastric cancer (GC) represents a significant burden of cancer-related mortality worldwide, underscoring an urgent need for the development of early detection strategies and precise postoperative interventions....
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Article
Open AccessElastic properties and tensile strength of 2D Ti3C2Tx MXene monolayers
Two-dimensional (2D) transition metal nitrides and carbides (MXenes), represented by Ti3C2Tx, have broad applications in flexible electronics, electromechanical devices, and structural membranes due to their uniq...
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Article
On physics of boundary vorticity creation in incompressible viscous flow
The present paper provides some arguments surrounding the controversies of boundary vorticity creation for incompressible viscous flow. Our discussion shows that boundary vorticity creation must be a viscous p...
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Article
Similarity of Chinese and Pakistani oral microbiome
Oral microbiota is vital for human health and can be affected by various factors (i.e. diets, ethnicity). However, few studies have compared oral microbiota of individuals from different nationalities in the s...
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Article
Open AccessSynthesis of 2D layered transition metal (Ni, Co) hydroxides via edge-on condensation
Layered transition metal hydroxides (LTMHs) with transition metal centers sandwiched between layers of coordinating hydroxide anions have attracted considerable interest for their potential in develo** clean...
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Article
Open AccessMaternal smoking, nutritional factors at different life stage, and the risk of incident type 2 diabetes: a prospective study of the UK Biobank
This study aims to investigate potential interactions between maternal smoking around birth (MSAB) and type 2 diabetes (T2D) pathway-specific genetic risks in relation to the development of T2D in offspring. A...
