24 Result(s)
within
Stephen M. Ansell
Biomedicine
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Article
Open AccessTwo types of amyloidosis presenting in a single patient: a case series
The amyloidoses are a group of disorders with overlap** clinical presentations, characterized by aggregation and tissue deposition of misfolded proteins. The nature and source of the amyloidogenic protein de...
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Article
Open AccessReverse signaling via PD-L1 supports malignant cell growth and survival in classical Hodgkin lymphoma
Treatment with programmed death-1 (PD-1) blocking antibodies results in high overall response rates in refractory and relapsed classical Hodgkin lymphoma (cHL) patients, indicating that PD-1/PD-1 ligand intera...
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Article
Open AccessLoss of TNFAIP3 enhances MYD88L265P-driven signaling in non-Hodgkin lymphoma
MYD88 mutations are one of the most recurrent mutations in hematologic malignancies. However, recent mouse models suggest that MYD88L265P alone may not be sufficient to induce tumor formation. Interplay between M...
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Article
Open AccessDefining cure in multiple myeloma: a comparative study of outcomes of young individuals with myeloma and curable hematologic malignancies
Advances in therapy in recent years have led investigators to challenge the dogma that multiple myeloma (MM) is incurable. We assessed overall (OS) and progression-free survival (PFS) of young patients ( ≤ 50 ...
