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Open AccessExtended topological valley-locked surface acoustic waves
Stable and efficient guided waves are essential for information transmission and processing. Recently, topological valley-contrasting materials in condensed matter systems have been revealed as promising infra...
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Article
Open AccessGenomic signatures define three subtypes of EGFR-mutant stage II–III non-small-cell lung cancer with distinct adjuvant therapy outcomes
The ADJUVANT study reported the comparative superiority of adjuvant gefitinib over chemotherapy in disease-free survival of resected EGFR-mutant stage II–IIIA non-small cell lung cancer (NSCLC). However, not all ...
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Open AccessAutomatic detection of 39 fundus diseases and conditions in retinal photographs using deep neural networks
Retinal fundus diseases can lead to irreversible visual impairment without timely diagnoses and appropriate treatments. Single disease-based deep learning algorithms had been developed for the detection of dia...
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Open AccessMinor allele of rs55763075 located in MTHFR is associated with the risk of cognitive impairment after anesthesia via modulating miR-34b
This study aimed to investigate the association between cognitive impairment after general anesthesia and rs55763075 polymorphisms. We enrolled and grouped patients undergoing general anesthesia according to t...
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Open AccessEvidence of cortical thickness reduction and disconnection in high myopia
High myopia (HM) is associated with impaired long-distance vision. accumulating evidences reported that abnormal visual experience leads to dysfunction in brain activity in HM even corrected. However, whether ...
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Open AccessAuthor Correction: The Apostasia genome and the evolution of orchids
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessStructural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor
Sterol O-acyltransferase 1 (SOAT1) is an endoplasmic reticulum (ER) resident, multi-transmembrane enzyme that belongs to the membrane-bound O-acyltransferase (MBOAT) family. It catalyzes the esterification of cho...
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Open AccessThe Litsea genome and the evolution of the laurel family
The laurel family within the Magnoliids has attracted attentions owing to its scents, variable inflorescences, and controversial phylogenetic position. Here, we present a chromosome-level assembly of the Litsea c...
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Article
Open AccessHistidine kinase MHZ1/OsHK1 interacts with ethylene receptors to regulate root growth in rice
Ethylene plays essential roles during adaptive responses to water-saturating environments in rice, but knowledge of its signaling mechanism remains limited. Here, through an analysis of a rice ethylene-respons...
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Open AccessProbing the edge-related properties of atomically thin MoS2 at nanoscale
Defects can induce drastic changes of the electronic properties of two-dimensional transition metal dichalcogenides and influence their applications. It is still a great challenge to characterize small defects...
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Open AccessProbing the Fluxional Bonding Nature of Rapid Cope rearrangements in Bullvalene C10H10 and Its Analogs C8H8, C9H10, and C8BH9
Bullvalene C10H10 and its analogs semibullvalene C8H8, barbaralane C9H10, and 9-Borabarbaralane C8BH9 are prototypical fluxional molecules with rapid Cope rearrangements at finite temperatures. Detailed bonding a...
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Open AccessSeasonal variation of idiopathic benign paroxysmal positional vertigo correlates with serum 25-hydroxyvitamin D levels: a six-year registry study in Shanghai, China
Seasonal variation of benign paroxysmal positional vertigo (BPPV) occurrence has been reported in recent years. Whether the seasonality of BPPV also exists in Chinese patients and whether it correlates with se...
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Open AccessA high-efficiency L-band coaxial three-period relativistic Cherenkov oscillator
Miniaturization is one of the important research directions of low frequency high power microwave sources. This paper presents a three-period coaxial slow-wave structure L-band high-power microwave source. Bec...
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Open AccessA high-speed search engine pLink 2 with systematic evaluation for proteome-scale identification of cross-linked peptides
We describe pLink 2, a search engine with higher speed and reliability for proteome-scale identification of cross-linked peptides. With a two-stage open search strategy facilitated by fragment indexing, pLink ...
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Open AccessRelationships of Non-coding RNA with diabetes and depression
In order to study the molecular differences between type 2 diabetes mellitus (T2DM) and T2DM with depression (DD), we aimed to screen the differential expression of lncRNA, mRNA, and circRNA in the blood of pa...
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Open AccessGenetic map construction and QTL analysis of leaf-related traits in soybean under monoculture and relay intercrop**
Soybean (Glycine max L.) is an important food and oil crop widely planted by intercrop** in southwest China. The shade caused by intercrop** changes plant growth traits, such as soybean leaf and dry mass, the...
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Open AccessAuthor Correction: Identifying long-term stable refugia for relict plant species in East Asia
In the original version of this Article, an incorrect sample size was provided for the number of relict species (443 instead of 442) and the number of relict forests (423 instead of 422). These errors have bee...
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Open AccessOpsin gene expression regulated by testosterone level in a sexually dimorphic lizard
Expression of nuptial color is usually energetically costly, and is therefore regarded as an ‘honest signal’ to reflect mate quality. In order to choose a mate with high quality, both sexes may benefit from th...
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Open AccessIdentifying long-term stable refugia for relict plant species in East Asia
Today East Asia harbors many “relict” plant species whose ranges were much larger during the Paleogene-Neogene and earlier. The ecological and climatic conditions suitable for these relict species have not bee...
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Open AccessElectronic Health Record Driven Prediction for Gestational Diabetes Mellitus in Early Pregnancy
Gestational diabetes mellitus (GDM) is conventionally confirmed with oral glucose tolerance test (OGTT) in 24 to 28 weeks of gestation, but it is still uncertain whether it can be predicted with secondary use ...