2,477 Result(s)
within
Shi-** Zhu
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Article
Open AccessProstaglandin I2 signaling prevents angiotensin II-induced atrial remodeling and vulnerability to atrial fibrillation in mice
Atrial fibrillation (AF) is the most common arrhythmia, and atrial fibrosis is a pathological hallmark of structural remodeling in AF. Prostaglandin I2 (PGI2) can prevent the process of fibrosis in various tissue...
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Clinical analysis of DNA methylation in the diagnosis of cervical lesions
Currently, cervical cancer screening is primarily conducted through liquid-based thin-layer cytology (TCT) and HPV testing. However, TCT has low sensitivity, leading to a high false-negative rate. Although HPV...
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Property evolution and service life prediction of novel metallic materials for future lunar bases
While lunar bases have been a focus of development in recent years, the complex and extreme environment of the lunar surface remains a considerable challenge for lunar exploration. Unlike those on Earth, lunar...
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Open AccessSingle-cell sequencing depicts tumor architecture and empowers clinical decision in metastatic conjunctival melanoma
Conjunctival melanoma (CoM) is a potentially devastating tumor that can lead to distant metastasis. Despite various therapeutic strategies for distant metastatic CoM, the clinical outcomes remain unfavorable. ...
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Open AccessPreliminary clinical analysis and pathway study of S100A8 as a biomarker for the diagnosis of acute deep vein thrombosis
Herein, we aimed to identify blood biomarkers that compensate for the poor specificity of D-dimer in the diagnosis of deep vein thrombosis (DVT). S100A8 was identified by conducting protein microarray analysis...
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Open AccessFactors associated with intrinsic capacity impairment in hospitalized older adults: a latent class analysis
Intrinsic capacity (IC) is proposed by the World Health Organization (WHO) to promote healthy aging. Although some studies have examined the factors influencing IC, few studies have comprehensively confirmed l...
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Open AccessRoot-to-shoot signaling positively mediates source-sink relation in late growth stages in diploid and tetraploid wheat
Non-hydraulic root source signaling (nHRS) is a unique positive response to soil drying in the regulation of plant growth and development. However, it is unclear how the nHRS mediates the tradeoff between sour...
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Reduced intensity conditioning regimen of fludarabine, busulfan, ATG based haploidentical stem cell transplantation for older or unfit patients
Reduced-intensity conditioning (RIC) regimens allogeneic hematopoietic stem cell transplantation (HSCT) was developed for older patients or those with poor functional status. Haploidentical donor was appropria...
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Pedigree Analysis of Nonclassical Cholesteryl Ester Storage Disease with Dominant Inheritance in a LIPA I378T Heterozygous Carrier
Cholesterol ester storage disorder (CESD; OMIM: 278,000) was formerly assumed to be an autosomal recessive allelic genetic condition connected to diminished lysosomal acid lipase (LAL) activity due to LIPA gene a...
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Open AccessAn observational prospective study based on a large cohort of HIV-negative neurosyphilis patients with particular reference to the Jarisch-Herxheimer reaction
The purpose of this study is to outline a complete picture of Jarisch-Herxheimer reaction (JHR) in the central nervous system among HIV-negative neurosyphilis patients.
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TOPK Inhibition Enhances the Sensitivity of Colorectal Cancer Cells to Radiotherapy by Reducing the DNA Damage Response
Abnormal expression of T-lymphokine-activated killer cell-originated protein kinase (TOPK) was reported to be closely related to the resistance of prostate cancer to radiotherapy and to targeted drug resistanc...
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Large-scale whole-exome sequencing of neuropsychiatric diseases and traits in 350,770 adults
While numerous genomic loci have been identified for neuropsychiatric conditions, the contribution of protein-coding variants has yet to be determined. Here we conducted a large-scale whole-exome-sequencing st...
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The impact of an increased Fibrosis-4 index and the severity of hepatic steatosis on mortality in individuals living with diabetes
Data on the effects of liver fibrosis and hepatic steatosis on outcomes in individuals living with diabetes are limited. Therefore, we investigated the predictive value of the fibrosis and the severity of hepa...
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Angiotensin II type-2 receptor signaling facilitates liver injury repair and regeneration via inactivation of Hippo pathway
The angiotensin II type 2 receptor (AT2R) is a well-established component of the renin-angiotensin system and is known to counteract classical activation of this system and protect against organ damage. Pharma...
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Does scientific and technological innovation promote regional coordination of socio-economy, environment, and energy? Evidence from quantitative research in China
The study of coordinated cross-regional development led by scientific and technological innovation (STI) is vital in promoting high-quality development in China. However, there is limited research on the coord...
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Constructing highly safe and long-life calcium ion batteries based on hydratedvanadium oxide cathodes featuring a pillar structure
Calcium-ion batteries (CIBs) have generated intense interest due to the growing demand for safer, cheaper, and large-scale energy storage systems. However, their development is still in its infancy, owing to t...
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Application of UiO-66 and its composites for remediation and resource recovery of typical environmental contaminants: a review
UiO-66 series metal–organic framework materials (MOFs) are typical porous materials assembled by Zr4+ with a large mass-to-nucleus ratio and terephthalic acid ligands, which form tetrahedral and octahedral cages ...
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Synthesis of highly stable Ni nanoparticles via electrostatic self-assembly for enhanced hydrogen storage of MgH2
Magnesium-based hydrides have been widely recognized as an appropriate choice for solid-state hydrogen storage. However, its undesirable thermodynamics and sluggish hydrogenation/dehydrogenation kinetics are m...
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Open AccessMeasurement of absolute branching fractions of \( {\textrm{D}}_{\textrm{s}}^{+} \) hadronic decays
Using e+e− collision data collected at the BESIII detector at center-of-mass energies between 4.128 and 4.226 GeV, corresponding to an integrated luminosity of 7.33 fb−1, we determine the absolute branching fract...
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Effect of Chinese Medicine in Patients with COVID-19: A Multi-center Retrospective Cohort Study
To evaluate the effectiveness and safety of Chinese medicine (CM) in the treatment of coronavirus disease 2019 (COVID-19) in China.
