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Article
New severity assessment in cystic fibrosis: signal intensity and lung volume compared to LCI and FEV1: preliminary results
Magnetic resonance imaging (MRI) aids diagnosis in cystic fibrosis (CF) but its use in quantitative severity assessment is under research. This study aims to assess changes in signal intensity (SI) and lung vo...
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Article
Open AccessParaneoplastic syndrome in undifferentiated embryonic sarcoma of the liver
The undifferentiated embryonic sarcoma of the liver (UESL) is a rare, aggressive tumor mainly affecting children. Since UESL has no specific clinical symptoms or imaging characteristics, many cases of UESL are...
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Chapter and Conference Paper
Bayesian Neural Networks for Uncertainty Estimation of Imaging Biomarkers
Image segmentation enables to extract quantitative measures from scans that can serve as imaging biomarkers for diseases. However, segmentation quality can vary substantially across scans, and therefore yield ...
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Article
Open AccessState of affairs of hybrid imaging in Europe: two multi-national surveys from 2017
To assess the current state of hybrid imaging in Europe with respect to operations, reading and reporting, as well as qualification and training.
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Article
Comprehensive anatomical and functional imaging in patients with type I neurofibromatosis using simultaneous FDG-PET/MRI
To demonstrate the clinical use of FDG-PET/MRI for monitoring enlargement and metabolism of plexiform neurofibromas (PNF) in patients with neurofibromatosis type 1 (NF1), in whom the development of a malignant...
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Chapter
PET/MRI
PET/MRI is a relatively new hybrid imaging modality that is mainly used for oncologic imaging. The combination of MRI and PET in a single examination is of high potential value especially in pediatric oncologi...
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Article
Practice-based evidence for the clinical benefit of PET/CT—results of the first oncologic PET/CT registry in Germany
The purpose of this study was to evaluate the impact of PET/CT on clinical management of cancer patients based on a prospective data registry. The study was developed to inform consultations with public health...
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Article
ImFEATbox: a toolbox for extraction and analysis of medical image features
In medical imaging, the digital post-processing and analysis of acquired images has become an important research field. Topics include various applications of image processing and machine learning aiming to as...
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Article
Voxel-wise correlation of functional imaging parameters in HNSCC patients receiving PET/MRI in an irradiation setup
The purpose of this study was to demonstrate the feasibility of voxel-wise multiparametric characterization of head and neck squamous cell carcinomas (HNSCC) using hybrid multiparametric magnetic resonance ima...
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Article
Clinical use of cardiac PET/MRI: current state-of-the-art and potential future applications
Combined PET/MRI is a novel imaging method integrating the advances of functional and morphological MR imaging with PET applications that include assessment of myocardial viability, perfusion, metabolism of in...
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Article
Automated reference-free detection of motion artifacts in magnetic resonance images
Our objectives were to provide an automated method for spatially resolved detection and quantification of motion artifacts in MR images of the head and abdomen as well as a quality control of the trained archi...
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Chapter
Pediatric Imaging
Pediatric imaging has been identified as a key application of integrated PET/MRI. Apart from the relevant reduction in radiation exposure compared to PET/CT, PET/MRI offers a unique combination of high MR soft...
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Chapter and Conference Paper
Deep Shape Analysis on Abdominal Organs for Diabetes Prediction
Morphological analysis of organs based on images is a key task in medical imaging computing. Several approaches have been proposed for the quantitative assessment of morphological changes, and they have been w...
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Article
A semiquantitative MRI-Score can predict loss of lung function in patients with cystic fibrosis: Preliminary results
To evaluate the applicability of a semiquantitative MRI scoring system (MR-CF-S) as a prognostic marker for clinical course of cystic fibrosis (CF) lung disease.
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Article
Cardiac CT for Guiding Mitral Valve Interventions
The purpose of this paper is to review the current role of contrast-enhanced cardiac computed tomography (CT) in the peri-procedural planning of mitral valve (MV) repair.
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Article
Population-based imaging biobanks as source of big data
Advances of computational sciences over the last decades have enabled the introduction of novel methodological approaches in biomedical research. Acquiring extensive and comprehensive data about a research sub...
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Article
Diffusion-weighted echo planar MR imaging of the neck at 3 T using integrated shimming: comparison of MR sequence techniques for reducing artifacts caused by magnetic-field inhomogeneities
Our objective was to compare available techniques reducing artifacts in echo planar imaging (EPI)-based diffusion-weighed magnetic resonance imaging MRI (DWI) of the neck at 3 Tesla caused by B0-field inhomoge...
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Chapter
Technical Prerequisites of Population-Based Imaging
The main goal of population-based imaging is to gain insight into physiological and pathophysiological processes of individuals by assessing corresponding morphological and functional changes in the general po...
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Article
Defining optimal tracer activities in pediatric oncologic whole-body 18F-FDG-PET/MRI
To explore the feasibility of reducing administered tracer activities and to assess optimal activities for combined 18F-FDG-PET/MRI in pediatric oncology.
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Article
Open AccessC-arm computed tomography and volume perfusion computed tomography (VPCT)-based assessment of blood volume changes in hepatocellular carcinoma in prediction of midterm tumor response to transarterial chemoembolization: a single center retrospective trial
This study aims to evaluate immediate changes in perfusion parameters in hepatocellular carcinoma (HCC) to transarterial chemoembolization (TACE) in C-arm computed tomography (CT) and volume perfusion CT (VPCT...
