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Article
Distinctive Clinical Characteristics and Outcome of ILD-Onset Rheumatoid Arthritis and ACPA-Positive ILD: a Longitudinal Cohort of 282 Cases
The aim of this study is to investigate the clinical features and outcome of interstitial lung disease (ILD)-onset rheumatoid arthritis (RA) and anti-citrullinated protein antibody (ACPA)-positive ILD-only pat...
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Article
Fast long-axis strain: a simple, automatic approach for assessing left ventricular longitudinal function with cine cardiovascular magnetic resonance
In some cardiac pathologies, impairment of left ventricular (LV) longitudinal function may precede reduction in LV ejection fraction. This study investigates the effectiveness of a fast method to quantify long...
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Article
Tumor-associated antigen-based personalized dendritic cell vaccine in solid tumor patients
Tumor-associated antigens (TAAs) have been tested in various clinical trials in cancer treatment but the patterns of specific T cell response to personalized TAA immunization remains to be fully understood. We...
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Article
Open AccessThree-dimensional morphological analysis of the femoral neck torsion angle—an anatomical study
The femoral neck torsion angle (FNTA) is an important but often neglected parameter in assessments of the anatomical morphology of the femoral neck, which is often confused with the femoral neck anteversion an...
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Article
Diagnosis and treatment of herpangina: Chinese expert consensus
Herpangina is a common infectious disease in childhood caused by an enterovirus. This consensus is aiming to standardize and improve herpangina prevention and clinical diagnosis.
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Article
The efficacy and safety of antithrombotic therapy in patients with positive antiphospholipid antibodies receiving invasive procedures: experience from a single tertiary center
To evaluate the efficacy and safety of antithrombotic prophylaxis and to explore potential risk factors for thrombotic/bleeding events in patients with positive antiphospholipid (aPL) antibodies receiving inva...
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Article
Quantification of fat deposition in the testis and epididymis using mDIXON Quant sequence: correlation with age and ejaculation
The objective of this study was to quantitatively assess fat deposition in the testis and epididymis by measuring the fat/water signal ratios with mDIXON Quant and to investigate its correlation with age and e...
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Article
Strength of suture-button fixation versus ligament reconstruction in syndesmotic injury: a biomechanical study
To compare the biomechanical characteristics of suture-button fixation versus ligament reconstruction using semitendinosus tendon autograft in treatment of syndesmotic injury in cadaver biomechanical study.
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Article
Open AccessValidation of a rapid semi-automated method to assess left atrial longitudinal phasic strains on cine cardiovascular magnetic resonance imaging
Abnormal left atrial (LA) function is a marker of cardiac dysfunction and adverse cardiovascular outcome, but is difficult to assess, and hence not, routinely quantified. We aimed to determine the feasibility ...
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Article
Open AccessFructus Ligustri Lucidi modulates estrogen receptor expression with no uterotrophic effect in ovariectomized rats
Accumulating evidence suggests that Fructus Ligustri Lucidi (FLL) plays a beneficial role in preventing the development of osteoporosis. However, the effects of FLL on estrogen receptor (ER) α and ERβ expressions...
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Chapter
Metabolic and Nutritional Skin Diseases
Metabolic and nutritional skin diseases presented in this chapter comprise tuberous xanthoma associated with aortic stenosis, xanthoma disseminatum, lipoid proteinosis, necrobiosis lipoidica, juvenile xanthoma...
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Article
Evaluation of specific neural marker GAP-43 and TH combined with Masson-trichrome staining for forensic autopsy cases with old myocardial infarction
It has been a puzzling forensic task to determine the cause of death as a result of old myocardial infarction (OMI) in the absence of recognizable acute myocardial infarction. Recent studies indicated that the...
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Chapter
Other Genodermatoses
Besides genodermatoses with presentation of keratoderma, other hereditary cutaneous diseases and syndromes considered in this chapter are incontinentia pigmenti, epidermolysis bullosa simplex, recessive dystro...
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Chapter
Pigmentary Disorder
Pigmentary disturbance is a very common presentation among Chinese populations. This chapter covers a variety of skin disease characterized with hypopigmentation, hyperpigmentation, and other pigmentary manife...
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Article
Clinical observation on acupuncture plus occupation therapy for fine motor functions in children with spastic cerebral palsy
To observe the clinical effect of acupuncture plus occupation therapy for fine motor functions in children with spastic cerebral palsy.
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Article
Disrupted-in-Schizophrenia-1 Attenuates Amyloid-β Generation and Cognitive Deficits in APP/PS1 Transgenic Mice by Reduction of β-Site APP-Cleaving Enzyme 1 Levels
Disrupted-in-Schizophrenia-1 (DISC1) is a genetic risk factor for a wide range of major mental disorders, including schizophrenia, major depression, and bipolar disorders. Recent reports suggest a potential ro...
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Article
Open AccessProtective effects of extracts from Pomegranate peels and seeds on liver fibrosis induced by carbon tetrachloride in rats
Liver fibrosis is a feature in the majority of chronic liver diseases and oxidative stress is considered to be its main pathogenic mechanism. Antioxidants including vitamin E, are effective in preventing liver...
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Article
Apelin-APJ effects of ginsenoside-Rb1 depending on hypoxia-induced factor 1α in hypoxia neonatal cardiomyocytes
To investigate whether ginsenoside-Rb1 (Gs-Rb1) inhibits the apoptosis of hypoxia cardiomyocytes by up-regulating apelin-APJ system and whether the system is affected by hypoxia-induced factor 1α (Hif-1α).
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Article
Gender Differences on Osteoporosis Health Beliefs and Related Behaviors in Non-academic Community Chinese
Osteoporosis represents the major public health concern worldwide. The purpose of this study was to assess osteoporosis beliefs and actual performance of osteoporosis preventive behaviors in non-academic commu...
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Article
Progesterone Regulates Secretin Expression in Mouse Uterus During Early Pregnancy
Secretin, a classical gastrointestinal and neuroendocrine peptide, plays an important role in maintaining the body fluid balance. However, the expression and regulation of secretin in the reproductive system a...