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  1. Article

    Open Access

    Association of body temperature and mortality in critically ill patients: an observational study using two large databases

    Body temperature (BT) is routinely measured and can be controlled in critical care settings. BT can impact patient outcome, but the relationship between BT and mortality has not been well-established.

    Daniel J. Tan, Jiayang Chen, Yirui Zhou in European Journal of Medical Research (2024)

  2. Article

    Open Access

    The association between blood lipids and cognitive impairment in type 2 diabetes mellitus

    The study was performed to explore the association between blood lipids and cognitive impairment in patients with type 2 diabetes mellitus (T2DM).

    Li Ma, Yue-**ng Yuan, Feng-** Cheng, Yan Liu in European Journal of Medical Research (2024)

  3. Article

    Open Access

    Ubiquitin-conjugating enzyme E2C (UBE2C) is a prognostic indicator for cholangiocarcinoma

    Cholangiocarcinoma is the most common malignant bile duct tumor in Southeast Asia. The special location of cholangiocarcinoma leads to it being difficult to diagnose. Currently, the progress in clinical progno...

    Khaa Hoo Ong, Hong-Yue Lai, Ding-** Sun in European Journal of Medical Research (2023)

  4. Article

    Open Access

    MRPL48 is a novel prognostic and predictive biomarker of hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is one of the most prevalent forms of cancer and poses a threat to the health and survival of humans. Mitochondrial ribosomal protein L48 (MRPL48) belongs to the mitochondrial ri...

    Yu-**ang Lin, Jun-Yong Pan, Wen-Du Feng in European Journal of Medical Research (2023)

  5. Article

    Open Access

    Comparison of different internal fixation models in ankle arthrodesis using 3D finite-element analysis

    The purpose of this study is to use three-dimensional finite-element analysis to better understand the biomechanical features of various internal fixators for ankle arthrodesis.

    Bo Feng, Qing-bo Gao, Guang-ming Dai, Ke-cheng Niu in European Journal of Medical Research (2023)

  6. Article

    Open Access

    Network pharmacology‑based investigation of potential targets of triptonodiol acting on non-small-cell lung cancer

    Triptonodiol is a very promising antitumor drug candidate extracted from the Chinese herbal remedy Tripterygium wilfordii Hook. F., and related studies are underway.

    Feng **, **aochen Ni, Shilong Yu, **aomin Jiang in European Journal of Medical Research (2023)

  7. Article

    Open Access

    The FDA-approved anti-amyloid-β monoclonal antibodies for the treatment of Alzheimer’s disease: a systematic review and meta-analysis of randomized controlled trials

    Alzheimer’s disease (AD) is a worldwide public health problem and is difficult to cure. Drugs aimed at slowing the progression of the disease have been developed, with the Food and Drug Administration (FDA) gr...

    Wenxue Wu, Yi Ji, Zilan Wang, **aoxiao Wu in European Journal of Medical Research (2023)

  8. Article

    Open Access

    CD72, a new immune checkpoint molecule, is a novel prognostic biomarker for kidney renal clear cell carcinoma

    The incidence and mortality of clear cell carcinoma of the kidney increases yearly. There are limited screening methods and advances in treating kidney renal clear cell carcinoma (KIRC). It is important to fin...

    Lv Tian, Yiming Wang, Zhiyuan Zhang, Xuechao Feng in European Journal of Medical Research (2023)

  9. Article

    Open Access

    CENPE and LDHA were potential prognostic biomarkers of chromophobe renal cell carcinoma

    Most sarcomatoid differentiated renal cell carcinoma was differentiated from Chromophobe renal cell carcinoma (KICH) and related to a bad prognosis. Thus, finding biomarkers is important for the therapy of KICH.

    Hui-feng Wu, Hao Liu, Zhe-wei Zhang, Ji-min Chen in European Journal of Medical Research (2023)

  10. Article

    Open Access

    Systemic inflammation response index as a clinical outcome evaluating tool and prognostic indicator for hospitalized stroke patients: a systematic review and meta-analysis

    Stroke, which is the main element of cerebrovascular disease (CVD), has become the foremost reason for death and disability on a global scale. The systemic inflammation response index (SIRI), a newly developed...

    Yong-Wei Huang, Ye Zhang, Cui Feng, Yin-Hua An in European Journal of Medical Research (2023)

  11. Article

    Open Access

    Upregulation of BMP1 through ncRNAs correlates with adverse outcomes and immune infiltration in clear cell renal cell carcinoma

    Renal cell carcinoma (RCC) accounts for approximately 2–3% of all adult malignancies. Clear cell renal cell carcinoma (ccRCC), which comprises 70–80% of all RCC cases, is the most common histological subtype.

    Mancheng Gong, Shengxing Feng, Dongsheng Zhou in European Journal of Medical Research (2023)

  12. Article

    Open Access

    Coagulation parameters for the differential diagnosis of pancreatic cancer in the early stage: a retrospective study

    In recent years, conventional coagulation (CC) and thromboelastography (TEG) parameters have been reported to be closely related to the progression of pancreatic cancer (PC). However, the potential utility of ...

    Li Jiaao, Ge Wanli, Zhang Kai, Guo Feng in European Journal of Medical Research (2023)

  13. Article

    Open Access

    What should we expect when two myositis-specific antibodies coexist in a patient

    The coexistence of two myositis-specific autoantibodies (MSA) is considered extremely rare. We describe three patients with both anti-signal recognition particle (SRP) antibodies and another MSA in serum.

    Yiming Zheng, Yawen Zhao, Hongjun Hao, Zhaoxia Wang in European Journal of Medical Research (2023)

  14. Article

    Open Access

    Association between ferritin to albumin ratio and 28-day mortality in patients with sepsis: a retrospective cohort study

    The ratio of ferritin to albumin (FAR) has been proposed as a novel prognostic indicator for COVID-19. However, the role of FAR in predicting the all-cause mortality rate in patients with sepsis has not been e...

    Feng Liu, Zhengting Liu in European Journal of Medical Research (2023)

  15. Article

    Open Access

    Pediatric adrenocortical carcinoma: clinical features and application of neoadjuvant chemotherapy

    To summarize the clinical characteristics of children with adrenocortical carcinoma (ACC) and preliminarily explore the indications for and efficacy of neoadjuvant chemotherapy in certain patients.

    Yu Lin, Shen Yang, Wei Yang, Haiyan Cheng in European Journal of Medical Research (2023)

  16. Article

    Open Access

    Comparison of clinical characteristics between adult-onset and juvenile-onset non-radiographic axial spondyloarthritis in Chinese patients: results from the COCAS cohort

    Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic disease predominantly affecting the axial skeleton. We aimed to describe the clinical characteristics of patients with non-radiographic axSpA...

    Shu-**n Huang, Hao-Guang Li, Hong-** Liang in European Journal of Medical Research (2023)

  17. Article

    Open Access

    Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma

    Melanoma is the deadliest form of skin tumor, and G protein-coupled receptors (GPCRs) play crucial roles in its carcinogenesis. Furthermore, the tumor microenvironment (TME) affects the overall survival (OS) a...

    Kangjie Shen, Qiangcheng Wang, Lu Wang, Yang Yang in European Journal of Medical Research (2023)

  18. Article

    Open Access

    Association between adiposity and facial aging: results from a Mendelian randomization study

    Skin, as a sociologically meaningful interface, has psychological implications different from other organs, particularly in the context of the global population aging. Growing evidence suggests that facial agi...

    Meiqi Liu, **gwei Feng in European Journal of Medical Research (2023)

  19. Article

    Open Access

    Construction of a prediction model for rebleeding in patients with acute upper gastrointestinal bleeding

    The incidence of rebleeding in patients with upper gastrointestinal bleeding (UGIB) remains despite advances in intervention approaches. Therefore, early prediction of the risk of rebleeding could help to grea...

    Yang** Zhuang, Shaohuai **a, Junwei Chen, Jun Ke in European Journal of Medical Research (2023)

  20. Article

    Open Access

    Bacterial lipopolysaccharide-induced endothelial activation and dysfunction: a new predictive and therapeutic paradigm for sepsis

    Lipopolysaccharide, a highly potent endotoxin responsible for severe sepsis, is the major constituent of the outer membrane of gram-negative bacteria. Endothelial cells participate in both innate and adaptive ...

    Min Wang, Jun Feng, Daixing Zhou, Junshuai Wang in European Journal of Medical Research (2023)

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