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Article
Differential Effects of Acute Serotonin and Dopamine Depletion on Prepulse Inhibition and P50 Suppression Measures of Sensorimotor and Sensory Gating in Humans
Schizophrenia is associated with impairments of sensorimotor and sensory gating as measured by prepulse inhibition (PPI) of the acoustic startle response and P50 suppression of the auditory event-related poten...
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Article
Acute high-dose glycine attenuates mismatch negativity (MMN) in healthy human controls
Schizophrenia is commonly associated with impairments in pre-attentive change detection as represented by reduced mismatch negativity (MMN). The neurochemical basis of MMN has been linked to N-methyl-d-aspartate ...
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Article
High-dose glycine inhibits the loudness dependence of the auditory evoked potential (LDAEP) in healthy humans
The loudness dependence of the auditory evoked Potential (LDAEP) has been suggested to be a putative marker of central serotonin function, with reported abnormalities in clinical disorders presumed to reflect ...
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Article
Acute dopamine D1 and D2 receptor stimulation does not modulate mismatch negativity (MMN) in healthy human subjects
Schizophrenia is commonly associated with an impairment in pre-attentive change detection, as represented by reduced mismatch negativity (MMN), an auditory event related potential. While the neurochemical basi...
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Article
Acute Serotonin and Dopamine Depletion Improves Attentional Control: Findings from the Stroop Task
Schizophrenia is associated with impairments of attentional control on classic experimental paradigms such as the Stroop task. However, at a basic level the neurochemical mechanisms that may be responsible for...
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Article
Dopamine receptor stimulation does not modulate the loudness dependence of the auditory evoked potential in humans
The Loudness Dependence of the Auditory Evoked Potential (LDAEP) has been suggested as a reliable measure of central serotonin function in humans; however, its specificity for the serotonin system remains a to...
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Article
Estrogen Prevents 5-HT1A Receptor-Induced Disruptions of Prepulse Inhibition in Healthy Women
The sex steroid hormone, estrogen, has been proposed to be protective against schizophrenia. This study examined the effects of estrogen treatment on modulation of prepulse inhibition (PPI) by the serotonin-1A...
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Article
Combined D1/D2 receptor stimulation under conditions of dopamine depletion impairs spatial working memory performance in humans
The mesocortical dopamine system is regarded as an important modulator of working memory. While it has been established that stimulation of the D1/D2 receptor in primates can improve spatial working memory perfor...
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Article
Is the Loudness Dependence of the Auditory Evoked Potential a Sensitive and Selective In Vivo Marker of Central Serotonergic Function?
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Article
L-Tryptophan Challenge and Cognitive Deficits in Bipolar Disorder: Evidence for Hyperserotonergic and Hypodopaminergic Mechanisms
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Article
Antidepressants and Emotional Processing
