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Article
Open AccessNovel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling
Dendritic cells (DCs) are a complex group of cells that play a critical role in vertebrate immunity. Lymph-node resident DCs (LN-DCs) are subdivided into conventional DC (cDC) subsets (CD11b and CD8α in mouse;...
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Article
Transient aggregation of ubiquitinated proteins during dendritic cell maturation
Dendritic cells (DCs) are antigen-presenting cells with the unique capacity to initiate primary immune responses1. Dendritic cells have a remarkable pattern of differentiation (maturation) that exhibits highly sp...
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Protocol
Purification and Characterization of MHC Class II Containing Organelles in Mouse Bone-Marrow-Derived Dendritic Cells
The initiation and propagation of the immune responses is dependent on the ability of antigen-presenting cells (APC) to convert proteins into peptides, to load them intracellularly onto major histocompatibilit...
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Chapter
Intelligent Decision Making Systems: From Medical Diagnosis to Vocational Guidance
This tutorial paper bas been written for physicians, biologists, more generally decision makers, who are beginners or little familiar with fuzzy sets theory and applications. The methodology that is presented ...
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Article
Developmental regulation of MHC class II transport in mouse dendritic cells
Dendritic cells (DCs) have the unique capacity to initiate primary and secondary immune responses1,2,3. They acquire antigens in peripheral tissues and migrate to lymphoid organs where they present processed pept...
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Chapter and Conference Paper
Influence of Thickness and Curvature on the Formability of Metal Sheets
An overall theory modelizing the onset of necking is presented. The first developments were made on the assumption that the fields considered were uniform (stresses, strains…). But this didn’t allow us to take...